Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which exercise advice is recommended for intermittent claudication?
AStopping walking at the very first twinge of pain each time
BComplete bed rest until the leg pain has gone for at least a month
CSupervised walking until pain is near maximal, then rest and repeat
DWalking only on days when the legs feel warm and painless
2.Med-surg: cardiovascular & respiratoryHard
During drainage of a large pleural effusion, a patient starts coughing and feels tight in the chest. What should the nurse do?
AStop or clamp the drainage and inform the doctor
BLie the patient flat until the drainage is complete
CSpeed up the drainage to finish quickly
DAsk the patient to cough harder to help the flow
3.Med-surg: neuro, endocrine & renalMedium
Which picture fits Brown-Séquard syndrome?
AWeakness on the same side and loss of pain on the opposite side
BLoss of all feeling but normal movement on both sides
CWeakness of both arms with normal strength in the legs
DParalysis of both legs, with normal sensation everywhere in the body
4.Med-surg: neuro, endocrine & renalHard
A patient with renal colic has normal kidney function and no other contraindications. Which drug is usually the first choice for pain?
AOral paracetamol (acetaminophen) alone
BAn oral antihistamine such as cetirizine
CA benzodiazepine such as diazepam
DAn NSAID such as diclofenac
5.Med-surg: GI, perioperative & oncologyMedium
A patient with a new colostomy asks what to eat at home. Which advice is most appropriate?
AEat only liquids until the stoma is removed
BEat a normal, balanced diet and introduce foods gradually
CAvoid all fruit and vegetables for the rest of their life
DDrink as little fluid as possible to reduce output
6.Med-surg: GI, perioperative & oncologyHard
A worker has a hydrofluoric acid burn on the hand and severe pain. After irrigation with water, which specific treatment is commonly applied?
ACalcium gluconate gel
BIce cubes wrapped in a cloth
CSodium bicarbonate paste
DSilver sulfadiazine cream
7.Clinical nursingMedium
Which electrolyte disturbance is most dangerous for the heart rhythm?
ALow sodium
BHigh chloride
CHigh or low potassium
DLow phosphate
8.Clinical nursingHard
A patient with long-standing COPD has an arterial blood gas with pH 7.37, a raised PaCO2 and a raised bicarbonate. How is this best described?
AAcute respiratory acidosis
BCompensated respiratory acidosis
CMixed metabolic and respiratory alkalosis
DUncompensated metabolic alkalosis
9.Lab values & electrolytesMedium
A patient with hepatic encephalopathy is receiving lactulose. Which finding best shows that the treatment is effective?
ASix to eight watery stools a day with dizziness
BA rising serum ammonia with a slower flapping tremor
CNo bowel movement for 2 days and calm sleep
DTwo to three soft stools a day and clearer thinking
10.Lab values & electrolytesHard
An RN cares for a patient on a 24-hour urine collection. Which task can be delegated to unlicensed assistive personnel (UAP), such as a nursing or healthcare assistant?
ADeciding whether to restart the collection after a missed sample
BInterpreting the creatinine clearance result when it comes back
CTeaching the patient why the 24-hour collection is needed
DSaving all urine in the collection container as instructed
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.37, PaCO₂ 54 mmHg (7.2 kPa) and HCO₃⁻ 30 mmol/L. The primary disorder is respiratory acidosis. How far is it compensated? Click your answer.
pH 7.37PaCO₂ 54 mmHg (7.2 kPa)HCO₃⁻ 30 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 50% oxygen shows PaO₂ 92 mmHg (12.3 kPa) and PaCO₂ 55 mmHg (7.3 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus arrhythmia
2normal sinus rhythm
3sinus bradycardia
4sinus tachycardia
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A woman calls to say her husband suddenly has a drooping face and slurred speech. What should the nurse advise?
ABook an appointment with his doctor next week
BDrive him to the hospital yourself after he has eaten dinner
CCall emergency services now and note the time it started
DLet him lie down and see if it improves
16.Prioritization & delegationHard
A patient receiving comfort-focused end-of-life care is distressed by breathlessness. Which approach is most appropriate?
AStart a series of aggressive tests to find the exact cause of the breathlessness
BWithhold all opioids because they may slow breathing
CLeave the patient alone so they can rest
DGive prescribed opioids and use positioning and a fan to relieve breathlessness
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Supervised walking until pain is near maximal, then rest and repeat
Why this is the answer
Supervised exercise programmes, walking to near-maximal claudication pain, resting and repeating for about 30 minutes several times a week, improve walking distance. With smoking cessation, an antiplatelet and a statin, this is first-line management.
Answer
C · Supervised walking until pain is near maximal, then rest and repeat
2.Med-surg: cardiovascular & respiratory
Answer: A · Stop or clamp the drainage and inform the doctor
Why this is the answer
Rapid removal of a large effusion can cause re-expansion pulmonary oedema. Coughing, chest tightness or pain are warning signs. Drainage is stopped and the doctor is informed, and the volume is usually drained in a controlled way.
Answer
A · Stop or clamp the drainage and inform the doctor
3.Med-surg: neuro, endocrine & renal
Answer: A · Weakness on the same side and loss of pain on the opposite side
Why this is the answer
Damage to one side of the spinal cord, often from a stab wound, causes motor loss and loss of proprioception on the same side, and loss of pain and temperature on the opposite side. The pain fibres cross soon after entering the cord.
Answer
A · Weakness on the same side and loss of pain on the opposite side
4.Med-surg: neuro, endocrine & renal
Answer: D · An NSAID such as diclofenac
Why this is the answer
NSAIDs are recommended first line for renal colic in suitable patients because they reduce prostaglandin-driven pain and ureteric spasm. Opioids are added if needed. NSAIDs are avoided in kidney impairment.
Answer
D · An NSAID such as diclofenac
5.Med-surg: GI, perioperative & oncology
Answer: B · Eat a normal, balanced diet and introduce foods gradually
Why this is the answer
People with a colostomy can usually eat a normal diet. Foods are reintroduced gradually to see how each one affects gas, odour and output, and regular meals and fluids help.
Answer
B · Eat a normal, balanced diet and introduce foods gradually
6.Med-surg: GI, perioperative & oncology
Answer: A · Calcium gluconate gel
Why this is the answer
Hydrofluoric acid penetrates deeply and binds calcium and magnesium, causing severe pain and possible life-threatening hypocalcaemia. Calcium gluconate gel binds fluoride; serum calcium and heart rhythm are monitored in larger exposures.
Answer
A · Calcium gluconate gel
7.Clinical nursing
Answer: C · High or low potassium
Why this is the answer
Both hyperkalaemia and hypokalaemia can cause life-threatening arrhythmias. Potassium must never be given as an undiluted rapid IV bolus.
Answer
C · High or low potassium
8.Clinical nursing
Answer: B · Compensated respiratory acidosis
Why this is the answer
Chronic CO2 retention is offset by the kidneys retaining bicarbonate, bringing the pH back to normal. A normal pH with high PaCO2 and high bicarbonate is a compensated respiratory acidosis.
Answer
B · Compensated respiratory acidosis
9.Lab values & electrolytes
Answer: D · Two to three soft stools a day and clearer thinking
Why this is the answer
Lactulose acidifies the colon, traps ammonia and speeds its removal, so the goal is usually about 2–3 soft stools a day with improving mental status. Too much lactulose can cause severe diarrhea, dehydration and electrolyte loss.Checked against:Lactulose · MedlinePlus (NIH) (2024)
Answer
D · Two to three soft stools a day and clearer thinking
10.Lab values & electrolytes
Answer: D · Saving all urine in the collection container as instructed
Why this is the answer
UAP can help with routine, standard tasks such as saving urine and keeping the container cool as instructed. Teaching, clinical decisions and interpreting results require nursing judgment and stay with the RN.Checked against:24-Hour Urine Collection and Analysis · StatPearls (NCBI Bookshelf) (2024)
Answer
D · Saving all urine in the collection container as instructed
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.37: within 7.35–7.45
PaCO₂ 54 mmHg: high (35–45)
HCO₃⁻ 30 mmol/L: high (22–26)
Compensation
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: A–a gradient = 195.8 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 21 small boxes, 1500 ÷ 21 ≈ 71 per minute.
2. Rhythm: regular, every R–R is 0.84 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
normal sinus rhythm
Answer
normal sinus rhythm
14.ECG rhythm strip interpretation
Answer: PR interval
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 24 small boxes, 1500 ÷ 24 ≈ 63 per minute.
2. Rhythm: regular, every R–R is 0.96 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.30 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
PR interval → first-degree AV block
Answer
PR interval
15.Prioritization & delegation
Answer: C · Call emergency services now and note the time it started
Why this is the answer
Stroke is time-critical. Emergency services can begin assessment on the way and take the patient to a stroke center; the time of onset guides treatment.
Answer
C · Call emergency services now and note the time it started
16.Prioritization & delegation
Answer: D · Give prescribed opioids and use positioning and a fan to relieve breathlessness
Why this is the answer
In palliative care, opioids are used to relieve breathlessness, along with positioning, a fan and calm reassurance. The aim is comfort, not more investigations.
Answer
D · Give prescribed opioids and use positioning and a fan to relieve breathlessness