Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which foot care advice is correct for a patient with peripheral arterial disease?
AWalk barefoot at home to strengthen the feet
BUse a hot water bottle on the feet at night
CCheck the feet daily and wear well-fitting shoes
DCut corns with a razor blade to prevent pressure
2.Med-surg: cardiovascular & respiratoryHard
A ventilated patient with severe ARDS is to be turned prone. What is the main reason, and the key nursing risk?
AIt treats infection; the risk is fever
BIt improves digestion and gut motility; the main risk is constipation
CIt improves oxygenation; risks are pressure injury and tube displacement
DIt lowers the blood pressure; the main risk is rebound hypertension
3.Med-surg: neuro, endocrine & renalMedium
Why might a patient bleed more from the needle sites straight after haemodialysis?
ADialysis removes all the platelets from the blood
BThe fistula has been damaged and must be tied off
CHeparin is often used to stop the circuit from clotting
DDialysis raises the blood pressure sharply for several hours
4.Med-surg: neuro, endocrine & renalHard
A patient on insulin has worsening chronic kidney disease and is having more hypos. What is the best explanation?
AThe kidneys clear less insulin, so it lasts longer
BKidney disease makes the body resistant to insulin
CThe patient is eating far more carbohydrate than before
DKidney disease makes the meter read too low
5.Med-surg: GI, perioperative & oncologyMedium
Which herbal supplement is commonly asked about before surgery because it may increase bleeding?
AChamomile
BPeppermint oil
CCranberry
DGinkgo biloba
6.Med-surg: GI, perioperative & oncologyHard
Four patients are on a gastroenterology ward. Which should the nurse see first?
AA patient with GORD who wants an antacid
BA patient with stable ulcerative colitis asking about diet
CA patient with cirrhosis who is newly confused and drowsy
DA patient with an ileostomy waiting to change the pouch
7.Clinical nursingMedium
A patient with type 1 diabetes is vomiting and eating little. What is correct sick-day advice?
ADo not stop insulin; check glucose and ketones more often
BStop insulin until eating normally again to avoid hypoglycaemia
CHalve fluid intake to prevent vomiting
DCheck glucose once a day only
8.Clinical nursingHard
Shortly after starting a transfusion, a patient becomes breathless, wheezy and hypotensive with facial swelling. What should the nurse do first?
AFinish the unit quickly so the exposure time is as short as possible
BStop the transfusion, keep IV access and call for urgent help
CGive paracetamol and an antihistamine and continue the transfusion
DSlow the transfusion rate and recheck the observations in an hour
9.Lab values & electrolytesMedium
A patient has had severe watery diarrhea for 4 days. Which laboratory pattern would the nurse expect?
ALow glucose and high magnesium
BLow potassium and low bicarbonate
CHigh potassium and high bicarbonate
DHigh sodium and high calcium
10.Lab values & electrolytesHard
Which patient's result should the nurse act on first?
AHemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
BPlatelets 140 × 10³/µL in a patient with mild chronic liver disease
CHemoglobin 9.6 g/dL (96 g/L) in a patient with stable chronic kidney disease
DFerritin 15 ng/mL in a well patient with known iron-deficiency anemia on oral iron
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.44, PaCO₂ 20 mmHg (2.7 kPa) and HCO₃⁻ 13 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.44PaCO₂ 20 mmHg (2.7 kPa)HCO₃⁻ 13 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.22, PaCO₂ 68 mmHg (9.1 kPa), HCO₃⁻ 27 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.22PaCO₂ 68 mmHg (9.1 kPa)HCO₃⁻ 27 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2first-degree AV block
3second-degree AV block type II
4junctional rhythm
15.Prioritization & delegationMedium
A patient’s chest tube becomes disconnected from the drainage system. What should the nurse do first?
APlace the end of the tube in a bottle of sterile water
BClamp the tube for the rest of the shift
CRemove the tube and cover the site
DWait for the provider to arrive before doing anything else
16.Prioritization & delegationHard
A nurse sees a colleague put a vial of an opioid into their own pocket instead of returning it. What should the nurse do?
ASay nothing, because it is not their business
BAsk the colleague to share the vial with them
CTell the patients to watch the colleague carefully
DReport it to the nurse manager according to policy
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Check the feet daily and wear well-fitting shoes
Why this is the answer
Reduced blood flow slows healing, so minor injuries can become ulcers or gangrene. Patients inspect their feet daily, keep them clean and moisturised, wear well-fitting footwear and see a podiatrist for nails and corns. Direct heat can burn ischaemic skin.
Answer
C · Check the feet daily and wear well-fitting shoes
2.Med-surg: cardiovascular & respiratory
Answer: C · It improves oxygenation; risks are pressure injury and tube displacement
Why this is the answer
Prone positioning improves ventilation–perfusion matching and oxygenation and improves survival in severe ARDS. Turning needs a trained team. Risks include accidental extubation or line removal and pressure damage to the face, chest and knees, so careful positioning and skin checks are essential.
Answer
C · It improves oxygenation; risks are pressure injury and tube displacement
3.Med-surg: neuro, endocrine & renal
Answer: C · Heparin is often used to stop the circuit from clotting
Why this is the answer
Heparin is commonly used during haemodialysis to prevent clotting in the circuit. Its effect can cause prolonged bleeding from puncture sites, so procedures such as IM injections may be timed with care.
Answer
C · Heparin is often used to stop the circuit from clotting
4.Med-surg: neuro, endocrine & renal
Answer: A · The kidneys clear less insulin, so it lasts longer
Why this is the answer
The kidneys clear a large share of insulin. As kidney function falls, insulin stays in the blood longer and some oral agents build up, so hypos increase. Insulin doses often need to be reduced.
Answer
A · The kidneys clear less insulin, so it lasts longer
5.Med-surg: GI, perioperative & oncology
Answer: D · Ginkgo biloba
Why this is the answer
Ginkgo, garlic, ginseng, fish oil and others may increase bleeding risk; St John's wort interacts with many drugs. Patients should report all supplements, and the surgical team advises whether to stop them before surgery.
Answer
D · Ginkgo biloba
6.Med-surg: GI, perioperative & oncology
Answer: C · A patient with cirrhosis who is newly confused and drowsy
Why this is the answer
New confusion and drowsiness in cirrhosis may be hepatic encephalopathy with a precipitant such as bleeding or infection, and the airway may be at risk. The others are stable.
Answer
C · A patient with cirrhosis who is newly confused and drowsy
7.Clinical nursing
Answer: A · Do not stop insulin; check glucose and ketones more often
Why this is the answer
Stopping insulin in type 1 diabetes can quickly cause DKA. Patients should continue insulin, monitor glucose and ketones, drink fluids and seek help if ketones rise.
Answer
A · Do not stop insulin; check glucose and ketones more often
8.Clinical nursing
Answer: B · Stop the transfusion, keep IV access and call for urgent help
Why this is the answer
Severe transfusion reactions, including anaphylaxis, require immediately stopping the transfusion, keeping venous access, following the ABCDE approach and treating anaphylaxis with IM adrenaline.
Answer
B · Stop the transfusion, keep IV access and call for urgent help
9.Lab values & electrolytes
Answer: B · Low potassium and low bicarbonate
Why this is the answer
Lower gut fluid contains potassium and bicarbonate, so severe diarrhea causes hypokalemia and a normal anion gap (hyperchloremic) metabolic acidosis, plus dehydration. Vomiting, in contrast, causes metabolic alkalosis.
Answer
B · Low potassium and low bicarbonate
10.Lab values & electrolytes
Answer: A · Hemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
Why this is the answer
Severe anemia with chest pain and tachycardia suggests the heart is not receiving enough oxygen, which needs urgent action, often including transfusion. The other results are mildly abnormal but expected or stable.
Answer
A · Hemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.44: within 7.35–7.45
PaCO₂ 20 mmHg: low (35–45)
HCO₃⁻ 13 mmol/L: low (22–26)
Compensation
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·2.8 = 26.8 mmol/L
chronic: 24 + 3.5·2.8 = 33.8 mmol/L
Compare
measured: 27 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: QTc = 0.52 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 13 × 0.04 = 0.52 s
RR = 25 × 0.04 = 1.00 s
Bazett’s formula
QTc = 0.52/√1.00 = 0.52/1 = 0.52 s
Answer
QTc = 0.52 s
Above 0.50 s: markedly prolonged. (520 ms)
14.ECG rhythm strip interpretation
Answer: third-degree (complete) AV block
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: R–R = 27 small boxes, 1500 ÷ 27 ≈ 56 per minute.
2. Rhythm: R–R regular (1.08 s) and P–P regular (0.80 s), but the two are independent.
3. P waves: upright and regular at 75 per minute, but not linked to the QRS complexes; some hide in a QRS or a T wave.
4. PR interval: varies from beat to beat; there is no fixed relation.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
third-degree (complete) AV block
Answer
third-degree (complete) AV block
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: A · Place the end of the tube in a bottle of sterile water
Why this is the answer
Putting the tube end in sterile water creates a temporary water seal until a new drainage system is connected. Long clamping can cause a tension pneumothorax, and the nurse does not remove the tube.
Answer
A · Place the end of the tube in a bottle of sterile water
16.Prioritization & delegation
Answer: D · Report it to the nurse manager according to policy
Why this is the answer
Suspected drug diversion must be reported through the proper channel, usually the manager. It protects patients and allows the colleague to get help; staying silent is not acceptable.
Answer
D · Report it to the nurse manager according to policy