Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why must intravenous potassium chloride never be given as a rapid push or undiluted?
AIt immediately lowers the blood glucose to dangerous levels
BIt turns into solid crystals inside the vein and blocks it
CA sudden high potassium level can cause cardiac arrest
DIt works only when given by mouth
2.Med-surg: cardiovascular & respiratoryHard
A patient's blood gas shows pH 7.26, PaCO₂ 9.0 kPa (68 mmHg) and bicarbonate 25 mmol/L. What does this show?
ARespiratory alkalosis
BMetabolic acidosis with compensation
CAcute respiratory acidosis
DMetabolic alkalosis
3.Med-surg: neuro, endocrine & renalMedium
A patient with atrial fibrillation has had an ischaemic stroke. Which long-term medicine type most reduces the risk of another stroke?
AAn oral anticoagulant
BA proton pump inhibitor
CA beta-agonist inhaler
DA loop diuretic
4.Med-surg: neuro, endocrine & renalHard
Three days after a stroke, a patient with dysphagia on a modified diet has a temperature of 38.2 °C (100.8 °F), a respiratory rate of 24/min and crackles at the right lung base. What should the nurse do?
AGive paracetamol (acetaminophen) and continue the modified diet as before
BSuspect aspiration pneumonia, stop oral intake and escalate for review
CRecord the findings and recheck them at the next routine observation
DEncourage more fluids by mouth to treat the fever
5.Med-surg: GI, perioperative & oncologyMedium
Which advice has good evidence for reducing cancer-related fatigue?
AComplete bed rest for the whole course of treatment
BDrinking several strong coffees every evening
CRegular light to moderate activity, such as walking
DAvoiding all daily activities
6.Med-surg: GI, perioperative & oncologyHard
A patient with a sacral pressure ulcer keeps sliding down the bed when the head is raised high. Which advice best reduces shear?
ARaise the head of the bed to 90° and pull the patient up the bed by the arms
BUse a dry sheet and drag the patient up the bed
CKeep the head of the bed at or below 30° if possible; use slide sheets
DSit the patient upright without any support for the feet
7.Clinical nursingMedium
How is Helicobacter pylori infection usually treated?
ASurgery to remove the stomach
BAntacids alone, taken after every meal for a month
CA combination of antibiotics with a proton pump inhibitor
DA single dose of paracetamol and a bland diet for a week
8.Clinical nursingHard
A patient with back pain develops numbness around the anus and genitals and new difficulty passing urine. Which condition should be suspected?
ASimple muscle strain
BCauda equina syndrome
CKidney stones
DConstipation
9.Lab values & electrolytesMedium
A patient had a total gastrectomy. Which long-term therapy is needed to prevent anemia?
AMonthly transfusions of red blood cells
BWeekly doses of oral vitamin K tablets
CLifelong vitamin B12 replacement
DLifelong oral folic acid tablets only
10.Lab values & electrolytesHard
A patient with severe vomiting has a potassium of 3.0 mEq/L, a chloride of 88 mEq/L and a high bicarbonate. What pattern does this show?
ALoss of stomach acid: low potassium and chloride, metabolic alkalosis
BNormal results that need no follow-up
CDiabetic ketoacidosis with a high anion gap
DHigh potassium with metabolic acidosis caused by dehydration
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.50, PaCO₂ 48 mmHg (6.4 kPa) and HCO₃⁻ 36 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.50PaCO₂ 48 mmHg (6.4 kPa)HCO₃⁻ 36 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 138, Cl⁻ 100, HCO₃⁻ 20 mmol/L and albumin 32 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2atrial fibrillation
3sinus arrhythmia
4sinus rhythm with PVCs
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 2:1 conduction
2supraventricular tachycardia (SVT)
3ventricular tachycardia
4ventricular fibrillation
15.Prioritization & delegationMedium
Which task should the nurse delegate to a nursing assistant for a patient on fall precautions?
ATeaching the family how to prevent falls at home
BDeciding whether the bed alarm is still needed
CHelping the patient to the toilet every 2 hours as planned
DAssessing and recording the patient’s fall risk score each morning
16.Prioritization & delegationHard
During JumpSTART triage, a child is not breathing after the airway is opened but has a palpable pulse. What is the next step?
AGive five rescue breaths; if breathing starts, tag the child red
BStart full CPR on the child and stay with them until more help arrives
CTag the child green and return to them after the others
DTag the child black at once and move on to the next victim
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · A sudden high potassium level can cause cardiac arrest
Why this is the answer
Rapid or concentrated IV potassium can cause cardiac arrest. It is given diluted, by infusion, at controlled rates (often with a pump and ECG monitoring for higher rates). Concentrated ampoules are tightly controlled in hospitals because of fatal errors.
Answer
C · A sudden high potassium level can cause cardiac arrest
2.Med-surg: cardiovascular & respiratory
Answer: C · Acute respiratory acidosis
Why this is the answer
A low pH with raised PaCO₂ is respiratory acidosis. A normal bicarbonate (about 22–26 mmol/L) shows the kidneys have not yet compensated, so the problem is acute, as in opioid toxicity, exhaustion or an acute COPD exacerbation. Treatment targets ventilation.
Answer
C · Acute respiratory acidosis
3.Med-surg: neuro, endocrine & renal
Answer: A · An oral anticoagulant
Why this is the answer
In AF the main cause of stroke is a clot from the left atrium. Oral anticoagulants such as a DOAC or warfarin prevent this far better than antiplatelets. The start date after a stroke depends on its size and bleeding risk.
Answer
A · An oral anticoagulant
4.Med-surg: neuro, endocrine & renal
Answer: B · Suspect aspiration pneumonia, stop oral intake and escalate for review
Why this is the answer
These signs suggest aspiration pneumonia, which is a common and serious complication of dysphagia. The patient needs medical review, chest assessment, oxygen if needed, and reassessment of their swallow before eating again.
Answer
B · Suspect aspiration pneumonia, stop oral intake and escalate for review
5.Med-surg: GI, perioperative & oncology
Answer: C · Regular light to moderate activity, such as walking
Why this is the answer
Exercise, matched to ability, reduces cancer-related fatigue. Pacing, prioritising activities, sleep routines and treating causes such as anaemia or depression also help.
Answer
C · Regular light to moderate activity, such as walking
6.Med-surg: GI, perioperative & oncology
Answer: C · Keep the head of the bed at or below 30° if possible; use slide sheets
Why this is the answer
A high head position makes patients slide, causing shear on the sacrum. A lower head position when clinically possible, knee break or foot support, and slide sheets for moving reduce shear and friction.
Answer
C · Keep the head of the bed at or below 30° if possible; use slide sheets
7.Clinical nursing
Answer: C · A combination of antibiotics with a proton pump inhibitor
Why this is the answer
Eradication therapy combines a PPI with two antibiotics for a set course. Completing the course is important for success.
Answer
C · A combination of antibiotics with a proton pump inhibitor
8.Clinical nursing
Answer: B · Cauda equina syndrome
Why this is the answer
Saddle anaesthesia, bladder or bowel dysfunction and leg symptoms with back pain suggest cauda equina syndrome. It needs an emergency MRI and surgical review to prevent permanent loss of function.
Answer
B · Cauda equina syndrome
9.Lab values & electrolytes
Answer: C · Lifelong vitamin B12 replacement
Why this is the answer
Intrinsic factor from the stomach is needed to absorb vitamin B12 in the ileum. After a total gastrectomy, B12 must be replaced for life, usually by injection, to prevent macrocytic anemia and nerve damage.Checked against:Vitamin B12 or folate deficiency anaemia - Causes · NHS (2023); Vitamin B12 deficiency anemia · MedlinePlus (NIH) (2026)
Answer
C · Lifelong vitamin B12 replacement
10.Lab values & electrolytes
Answer: A · Loss of stomach acid: low potassium and chloride, metabolic alkalosis
Why this is the answer
Vomiting removes hydrochloric acid, so chloride falls and bicarbonate rises (metabolic alkalosis). The kidneys then lose potassium. Replacement usually includes 0.9% sodium chloride with potassium as prescribed.Checked against:Alkalosis · StatPearls (NCBI Bookshelf) (2024)
Answer
A · Loss of stomach acid: low potassium and chloride, metabolic alkalosis
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.50: alkalaemia (above 7.45)
PaCO₂ 48 mmHg: high (35–45)
HCO₃⁻ 36 mmol/L: high (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: AGc = 20 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 138 − (100 + 20) = 18
Correction for albumin
18 + 0.25·(40 − 32) = 20 mmol/L
Answer
AGc = 20 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: sinus arrhythmia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 7 QRS complexes in 6 s, × 10 = 70 per minute.
2. Rhythm: irregular, R–R from 0.78 to 1.10 s, lengthening and shortening gradually.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
sinus arrhythmia
Answer
sinus arrhythmia
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.16 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: C · Helping the patient to the toilet every 2 hours as planned
Why this is the answer
A scheduled toileting round is a routine task that follows the care plan. Scoring fall risk, deciding on interventions and teaching need nursing judgement.
Answer
C · Helping the patient to the toilet every 2 hours as planned
16.Prioritization & delegation
Answer: A · Give five rescue breaths; if breathing starts, tag the child red
Why this is the answer
In JumpSTART, an apneic child with a pulse gets five rescue breaths, because the cause is often respiratory. If breathing starts the child is immediate (red); if not, the child is expectant.
Answer
A · Give five rescue breaths; if breathing starts, tag the child red