Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
How should a patient breathe in when using a pressurised metered-dose inhaler without a spacer?
ASlowly and deeply while pressing the canister, then hold the breath
BAs hard and fast as possible, then press the canister afterwards
CNormally, while breathing out through the mouthpiece
DIn short gasps through the nose while pressing the canister
2.Med-surg: cardiovascular & respiratoryHard
A patient with heart failure is breathless at rest, with cool peripheries, a systolic BP of 80 mmHg and falling urine output. What does this suggest?
AMild dehydration that oral fluids will correct
BAnxiety causing a vasovagal response
CStable, well-compensated chronic heart failure
DCardiogenic shock with poor tissue perfusion
3.Med-surg: neuro, endocrine & renalMedium
Before IV thrombolysis for stroke, which blood pressure limit is commonly used?
ABelow about 185/110 mmHg
BAbove about 200/120 mmHg
CThere is no blood pressure limit
DBelow about 90/60 mmHg
4.Med-surg: neuro, endocrine & renalHard
A patient with an insulin pump is admitted with nausea, a glucose of 19 mmol/L (342 mg/dL) and blood ketones of 3.1 mmol/L. What is the priority?
ADisconnect the pump and give no insulin until the ketones clear
BGive an antiemetic only, because nausea is causing the high glucose
CIncrease the pump rate and recheck the ketones in 12 hours
DSuspect failed insulin delivery and give insulin by another route
5.Med-surg: GI, perioperative & oncologyMedium
Which statement about moist wound healing is correct?
AA moist, not wet, wound bed helps cells move and heal faster
BWounds heal fastest when left to dry out and form a scab
CA wet wound bed always prevents infection
DWounds should be soaked in water for hours every day
6.Med-surg: GI, perioperative & oncologyHard
A colleague suggests giving a saline injection to see whether a patient's pain is "real". What is the best response?
AIt is a good idea, as long as the patient is not told about it afterwards
BIt is acceptable if a senior nurse gives the saline
CDeceptive placebos are unethical and do not show pain is "fake"
DIt should be done only for patients with chronic pain
7.Clinical nursingMedium
Why are patients advised to rinse their mouth after using an inhaled corticosteroid?
ATo stop the drug from being absorbed in the lungs
BTo make the drug work faster
CTo reduce the risk of oral thrush
DTo prevent tooth decay from the sugar in it
8.Clinical nursingHard
A patient who speaks little English needs to give consent for a procedure. Their 14-year-old child offers to interpret. What is the best action?
ALet the child interpret to save time
BAsk the patient to sign the form without explanation
CUse gestures and proceed
DArrange a professional interpreter
9.Lab values & electrolytesMedium
A urine culture report states "mixed growth of three organisms, likely contamination." What is the nurse's best response?
AStart treatment for all three organisms with three antibiotics
BRecord the result as a confirmed urinary tract infection
CInform the provider and arrange a new, correctly collected sample
DDiscard the report, because a mixed growth is always normal
10.Lab values & electrolytesHard
Which finding most strongly suggests that a patient’s raised creatinine is due to acute kidney injury rather than long-standing chronic kidney disease?
AThe patient has long-standing anemia
BThe patient has small kidneys on an ultrasound scan
CThe patient has had a high creatinine for many years
DThe creatinine was normal three days ago and has doubled since
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 57 mmHg (7.6 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2ventricular tachycardia
3ventricular fibrillation
4torsades de pointes
15.Prioritization & delegationMedium
Before giving a medication to a child, which check is especially important?
AThat the dose is correct for the child’s weight
BThat the parent agrees with the time it is given
CThat the medicine cup is the child’s favorite color
DThat the child likes the taste of the drug
16.Prioritization & delegationHard
Four patients arrive at the emergency department together. Who should be seen first?
AAn adult with a deformed ankle and a normal pulse in the foot
BA teenager with a cut on the arm whose bleeding is controlled
CA 2-year-old who is drooling, sitting forward and has stridor
DAn adult with a migraine and a blood pressure of 150/90 mmHg
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Slowly and deeply while pressing the canister, then hold the breath
Why this is the answer
With a metered-dose inhaler, the patient breathes out, starts a slow deep breath, presses the canister at the start of it and then holds the breath for about 10 seconds. Coordination is difficult, which is why spacers are often used.
Answer
A · Slowly and deeply while pressing the canister, then hold the breath
2.Med-surg: cardiovascular & respiratory
Answer: D · Cardiogenic shock with poor tissue perfusion
Why this is the answer
Cardiogenic shock is pump failure with hypotension and hypoperfusion (cool skin, oliguria, confusion, raised lactate), often with pulmonary congestion. It needs urgent critical care review. Large fluid boluses can worsen congestion unless guided by careful assessment.
Answer
D · Cardiogenic shock with poor tissue perfusion
3.Med-surg: neuro, endocrine & renal
Answer: A · Below about 185/110 mmHg
Why this is the answer
Many guidelines require blood pressure below 185/110 mmHg before thrombolysis and below 180/105 mmHg for 24 hours afterwards, because very high pressure increases the risk of haemorrhagic transformation. Higher readings are lowered carefully first.
Answer
A · Below about 185/110 mmHg
4.Med-surg: neuro, endocrine & renal
Answer: D · Suspect failed insulin delivery and give insulin by another route
Why this is the answer
Rising ketones in a pump user suggest that insulin delivery has failed, for example from a kinked cannula or an empty reservoir. Insulin must be given by pen or IV, and DKA treatment started if criteria are met. The site and pump are checked.
Answer
D · Suspect failed insulin delivery and give insulin by another route
5.Med-surg: GI, perioperative & oncology
Answer: A · A moist, not wet, wound bed helps cells move and heal faster
Why this is the answer
A moist environment supports cell migration, autolytic debridement and less pain. Too much moisture causes maceration, so dressings are chosen to balance exudate.
Answer
A · A moist, not wet, wound bed helps cells move and heal faster
6.Med-surg: GI, perioperative & oncology
Answer: C · Deceptive placebos are unethical and do not show pain is "fake"
Why this is the answer
A placebo response does not mean pain is not real, and giving placebos without consent is deceptive and damages trust. Pain is assessed with the patient and treated according to the plan.
Answer
C · Deceptive placebos are unethical and do not show pain is "fake"
7.Clinical nursing
Answer: C · To reduce the risk of oral thrush
Why this is the answer
Inhaled steroid deposited in the mouth and throat can cause oral candidiasis and a hoarse voice. Rinsing and using a spacer reduce this.
Answer
C · To reduce the risk of oral thrush
8.Clinical nursing
Answer: D · Arrange a professional interpreter
Why this is the answer
Professional interpreters provide accurate, impartial translation and protect confidentiality. Children and family members should not be used for important clinical discussions such as consent.
Answer
D · Arrange a professional interpreter
9.Lab values & electrolytes
Answer: C · Inform the provider and arrange a new, correctly collected sample
Why this is the answer
Several organisms in one urine sample usually mean contamination from the skin or perineum during collection. The provider is informed, and a new clean-catch or catheter-port sample is usually needed before an infection can be confirmed.
Answer
C · Inform the provider and arrange a new, correctly collected sample
10.Lab values & electrolytes
Answer: D · The creatinine was normal three days ago and has doubled since
Why this is the answer
A rapid rise from a normal baseline over days is the hallmark of acute kidney injury. Long-standing raised values, small kidneys and chronic anemia point to chronic kidney disease.Checked against:Acute Kidney Injury · StatPearls (NCBI Bookshelf) (2026)
Answer
D · The creatinine was normal three days ago and has doubled since
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 29.95 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|57 − 40| = 17 mmHg → 1.7 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·1.7 = 29.95 mmol/L
Answer
HCO₃⁻ = 29.95 mmol/L
12.Arterial blood gas interpretation
Answer: AGc = 18.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 140 − (110 + 13) = 17
Correction for albumin
17 + 0.25·(40 − 35) = 18.25 mmol/L
Answer
AGc = 18.25 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: QTc = 0.36 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 8.5 × 0.04 = 0.34 s
RR = 21 × 0.04 = 0.84 s
Fridericia’s formula
QTc = 0.34/∛0.84 = 0.34/0.9435 = 0.36 s
Answer
QTc = 0.36 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (360 ms)
14.ECG rhythm strip interpretation
Answer: ventricular fibrillation
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: chaotic, no repeating pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
ventricular fibrillation
Answer
ventricular fibrillation
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: A · That the dose is correct for the child’s weight
Why this is the answer
Pediatric doses are usually calculated by weight, and errors can cause serious harm. The nurse checks the dose against the child’s weight and the safe range before giving it.
Answer
A · That the dose is correct for the child’s weight
16.Prioritization & delegation
Answer: C · A 2-year-old who is drooling, sitting forward and has stridor
Why this is the answer
Drooling, a forward-leaning (tripod) position and stridor suggest a severe upper airway obstruction, such as epiglottitis, which can become complete quickly. The child should be kept calm and the throat not examined until airway experts are present.
Answer
C · A 2-year-old who is drooling, sitting forward and has stridor