Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
What is pulmonary rehabilitation in COPD?
AA lung function test repeated every six months
BSurgery to remove the most damaged areas of lung
CA course of oral steroids and antibiotics given at home each winter
DSupervised exercise and education that ease breathlessness
2.Med-surg: cardiovascular & respiratoryHard
During a severe asthma attack, a patient's PaCO₂ rises from low to normal while they look exhausted. What does this mean?
AThe patient is tiring and respiratory failure may follow
BThe patient is hyperventilating because of anxiety
CThe sample is probably venous and can be ignored
DThe attack is resolving and treatment can be reduced
3.Med-surg: neuro, endocrine & renalMedium
After pressing the plunger of an insulin pen, what should the patient do?
ALeave the needle on the pen for the next injection
BKeep the needle in the skin for about 10 seconds
CPull the needle out at once and rub the site firmly
DInject a second dose straight away to be sure
4.Med-surg: neuro, endocrine & renalHard
A patient with lung cancer is confused, dehydrated and constipated, with a corrected calcium of 3.4 mmol/L (about 13.6 mg/dL). What is usually the first treatment?
AIV fluids to rehydrate the patient
BIV calcium gluconate and vitamin D
COral calcium tablets
DA fluid restriction
5.Med-surg: GI, perioperative & oncologyMedium
Which measure helps reduce the risk of delirium in an older surgical patient?
AKeeping the room dark during the day
BMaking sure they have their glasses and hearing aids
CGiving a sleeping tablet every night
DMoving them to a new bed space each night to reduce boredom
6.Med-surg: GI, perioperative & oncologyHard
A patient with facial burns from a house fire was talking normally on arrival. Two hours later, the voice is hoarse and there is stridor. What should the nurse do?
ACall for urgent anaesthetic help, as the airway is swelling
BLay the patient flat to help them sleep
CEncourage the patient to rest the voice and reassess tomorrow
DGive a warm drink to soothe the throat
7.Clinical nursingMedium
When a patient returns to the ward from theatre, what should the nurse assess first?
AThe discharge date
BThe patient's dietary preferences for the next meal
CAirway, breathing, circulation and level of consciousness
DWhether visitors are waiting to see the patient
8.Clinical nursingHard
A seriously ill patient asks the nurse, "Am I dying?" What is the best initial response?
AChange the subject quickly to keep them cheerful and avoid upsetting them
BLeave and send the doctor without saying anything
CTell the patient not to think about such things and to stay positive
DGently explore what the patient understands and what has prompted the question
9.Lab values & electrolytesMedium
A patient has IV fluids running into the left forearm. Where should the nurse take a blood sample?
AFrom just above the IV site in the same arm
BFrom the IV cannula while the fluid is running
CFrom any vein, since the fluid does not affect results
DFrom the opposite arm
10.Lab values & electrolytesHard
A patient with a calcium of 6.8 mg/dL (1.7 mmol/L) suddenly develops noisy breathing and a hoarse voice. What does this suggest?
AAnxiety about the blood results, which needs calm reassurance
BA normal response that will pass without treatment
CLaryngospasm, an emergency needing urgent help and IV calcium
DA common cold that started this morning
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 6 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 6 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 136, Cl⁻ 110, HCO₃⁻ 14 mmol/L and albumin 19 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2first-degree AV block
3second-degree AV block type I (Wenckebach)
4atrial fibrillation
15.Prioritization & delegationMedium
A nurse receives four call lights at the same time. Which patient does the nurse go to first?
AA patient asking for pain medication for pain of 4/10
BA patient who says, “I can’t catch my breath.”
CA patient asking what time the doctor will come
DA patient whose IV pump is alarming for a finished bag of maintenance fluid
16.Prioritization & delegationHard
A patient taking an MAO inhibitor antidepressant is taught about diet. Which statement shows a need for further teaching?
A“I can still eat aged cheese and cured salami.”
B“I will avoid tap beer and red wine.”
C“I will check with the pharmacist before cold remedies.”
D“A sudden severe headache is a warning sign.”
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Supervised exercise and education that ease breathlessness
Why this is the answer
Pulmonary rehabilitation combines individually tailored exercise training, education and breathing techniques. It improves exercise capacity, breathlessness and quality of life and reduces hospital admissions. It is recommended for people with COPD who are limited by breathlessness and after an exacerbation.
Answer
D · Supervised exercise and education that ease breathlessness
2.Med-surg: cardiovascular & respiratory
Answer: A · The patient is tiring and respiratory failure may follow
Why this is the answer
Early in an attack, hyperventilation lowers PaCO₂. A normal or rising PaCO₂ in a breathless, tiring patient means ventilation is failing and is a life-threatening feature. Urgent senior and critical care review is needed.
Answer
A · The patient is tiring and respiratory failure may follow
3.Med-surg: neuro, endocrine & renal
Answer: B · Keep the needle in the skin for about 10 seconds
Why this is the answer
Holding the needle in place for around 10 seconds (or as the manufacturer advises) lets the full dose be delivered. A new needle is used for each injection, and the site should not be massaged.
Answer
B · Keep the needle in the skin for about 10 seconds
4.Med-surg: neuro, endocrine & renal
Answer: A · IV fluids to rehydrate the patient
Why this is the answer
Hypercalcaemia causes polyuria and dehydration, which worsen the high calcium. IV fluids are the first step, followed by a bisphosphonate to reduce bone resorption. Calcium is rechecked regularly.
Answer
A · IV fluids to rehydrate the patient
5.Med-surg: GI, perioperative & oncology
Answer: B · Making sure they have their glasses and hearing aids
Why this is the answer
Delirium prevention includes using glasses and hearing aids, orientation, good sleep, hydration, nutrition, early mobilisation, pain control, avoiding unnecessary sedatives and involving family.
Answer
B · Making sure they have their glasses and hearing aids
6.Med-surg: GI, perioperative & oncology
Answer: A · Call for urgent anaesthetic help, as the airway is swelling
Why this is the answer
Progressive hoarseness and stridor after a facial or inhalation burn mean the airway is narrowing. Early intubation by an experienced anaesthetist is needed before swelling makes it impossible. The patient is sat up and given oxygen.
Answer
A · Call for urgent anaesthetic help, as the airway is swelling
7.Clinical nursing
Answer: C · Airway, breathing, circulation and level of consciousness
Why this is the answer
Early postoperative assessment checks the airway, breathing, oxygen saturation, circulation, consciousness, pain, wound and drains. This detects anaesthetic and surgical complications early.
Answer
C · Airway, breathing, circulation and level of consciousness
8.Clinical nursing
Answer: D · Gently explore what the patient understands and what has prompted the question
Why this is the answer
Exploring the patient's understanding and feelings opens an honest conversation and shows what information they want. The nurse can then involve the team for further discussion.
Answer
D · Gently explore what the patient understands and what has prompted the question
9.Lab values & electrolytes
Answer: D · From the opposite arm
Why this is the answer
Blood taken near a running infusion is mixed with the IV fluid, causing false results, such as a high glucose or a low hemoglobin. The sample is taken from the other arm, or according to policy if that is not possible.
Answer
D · From the opposite arm
10.Lab values & electrolytes
Answer: C · Laryngospasm, an emergency needing urgent help and IV calcium
Why this is the answer
Severe hypocalcemia can cause spasm of the larynx, which blocks the airway. The nurse calls for urgent help, supports the airway and prepares IV calcium gluconate as prescribed, with cardiac monitoring.Checked against:Hypocalcemia (StatPearls) · StatPearls (NCBI Bookshelf) (2026)
Answer
C · Laryngospasm, an emergency needing urgent help and IV calcium
11.Arterial blood gas interpretation
Answer: PaCO₂ = 17 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·6 + 8 = 17 mmHg
range: 15–19 mmHg
Answer
PaCO₂ = 17 mmHg
12.Arterial blood gas interpretation
Answer: AGc = 17.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 136 − (110 + 14) = 12
Correction for albumin
12 + 0.25·(40 − 19) = 17.25 mmol/L
Answer
AGc = 17.25 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: pause = 2.36 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
59 small boxes from R to R across the pause
Convert
pause = 59 × 0.04 s = 2.36 s
Compare with P–P
2.36 ÷ 0.96 ≈ 2.5 P–P cycles, not a whole number
Answer
pause = 2.36 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 0.88 s, 68 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: lengthens 0.20 → 0.32 s, then a P wave is not conducted.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: B · A patient who says, “I can’t catch my breath.”
Why this is the answer
New difficulty breathing is a possible threat to life and needs assessment first. A finished maintenance bag, moderate pain and a question can be handled next.
Answer
B · A patient who says, “I can’t catch my breath.”
16.Prioritization & delegation
Answer: A · “I can still eat aged cheese and cured salami.”
Why this is the answer
MAO inhibitors with tyramine-rich foods, such as aged cheese and cured meats, can cause a hypertensive crisis. Patients avoid these foods, check medicines with a pharmacist and report a severe headache.
Answer
A · “I can still eat aged cheese and cured salami.”