Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
How is a patient usually positioned for a thoracentesis?
AProne with the arms by the sides
BFlat on the back with the legs raised
CSitting upright and leaning forward over a table
DLying on the affected side with the head down
2.Med-surg: cardiovascular & respiratoryHard
A patient had 40 minutes of chest pain at rest. The ECG shows ST depression without ST elevation, and the troponin is rising. What is the diagnosis?
AStable angina
BAcute pericarditis
CST-elevation myocardial infarction (STEMI)
DNon-ST-elevation myocardial infarction
3.Med-surg: neuro, endocrine & renalMedium
After a change in the levothyroxine dose, when is the TSH usually rechecked?
AAfter 24 hours
BAfter 3 days
CAfter about 2 years of treatment
DAfter about 6–8 weeks
4.Med-surg: neuro, endocrine & renalHard
A patient with multiple sclerosis has had worse leg weakness for one day, together with a fever and burning on passing urine. What is the most likely explanation?
AA change to progressive MS
BA true relapse that needs high-dose steroids
CA pseudo-relapse caused by infection
DA side effect of physiotherapy
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps a person with diabetes prevent foot ulcers?
AWear tight shoes to support the ankles
BSoak the feet in very hot water every evening
CCheck the feet every day and never walk barefoot
DCut corns off at home with a sharp blade
6.Med-surg: GI, perioperative & oncologyHard
A patient has negative pressure wound therapy. The pump alarms and the dressing has lost its seal. What is the most appropriate action?
ALeave the foam in the wound without suction for several days until review
BTurn the suction up to its maximum setting to pull the seal back
CRestore the seal; if that fails in time, change to a moist dressing
DPack the wound with dry gauze over the foam and tape it tightly
7.Clinical nursingMedium
A patient's abdomen is rigid and board-like, and they lie very still because movement worsens the pain. What does this suggest?
AConstipation
BUrinary tract infection
CIndigestion
DPeritonitis
8.Clinical nursingHard
After a viral illness, a patient has sharp chest pain that is worse lying flat and eased by sitting forward. What is the most likely cause?
APulmonary oedema
BStable angina
CPericarditis
DAortic dissection
9.Lab values & electrolytesMedium
A patient taking phenazopyridine for bladder pain has bright orange urine. What should the nurse know about urine tests?
AThe drug improves the accuracy of all dipsticks
BThe dye can interfere with dipstick color readings
CThe color shows severe liver failure is present
DThe color proves blood is present in the urine
10.Lab values & electrolytesHard
A patient in DKA is receiving IV fluids and insulin. The glucose has fallen to about 220 mg/dL (12.2 mmol/L), but the anion gap is still high. What change would the nurse expect?
AAdd dextrose to the IV fluids and continue the insulin
BStop the IV fluids and start oral fluids only
CStop the insulin infusion because the glucose is near normal
DGive an IV bolus of sodium bicarbonate at once
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 32 mmHg (4.3 kPa). Use the rule that in chronic respiratory alkalosis HCO₃⁻ falls by 5 mmol/L for every 10 mmHg that PaCO₂ is below 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
Measure the QT interval on this lead II strip, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QT = s
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1idioventricular rhythm
2paced rhythm, failure to capture
3dual-chamber (AV) paced rhythm
4second-degree AV block type II
15.Prioritization & delegationMedium
Which task is most appropriate for the RN to delegate to an LPN/LVN?
AInserting an indwelling urinary catheter in a stable patient
BGiving discharge teaching to a patient newly started on insulin
CDoing the admission assessment of a new patient
DStarting the first unit of red blood cells
16.Prioritization & delegationHard
A patient receiving comfort-focused end-of-life care is distressed by breathlessness. Which approach is most appropriate?
ALeave the patient alone so they can rest
BGive prescribed opioids and use positioning and a fan to relieve breathlessness
CStart a series of aggressive tests to find the exact cause of the breathlessness
DWithhold all opioids because they may slow breathing
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Sitting upright and leaning forward over a table
Why this is the answer
Sitting upright and leaning forward on a bedside table widens the intercostal spaces at the back and lets the fluid settle at the base. If the patient cannot sit, lying on the unaffected side may be used.
Answer
C · Sitting upright and leaning forward over a table
2.Med-surg: cardiovascular & respiratory
Answer: D · Non-ST-elevation myocardial infarction
Why this is the answer
An NSTEMI is an acute coronary syndrome with myocardial necrosis (rising troponin) but no persistent ST elevation; ST depression or T wave inversion may be seen. It is treated with antiplatelets, anticoagulation and angiography based on risk, rather than emergency reperfusion.
Answer
D · Non-ST-elevation myocardial infarction
3.Med-surg: neuro, endocrine & renal
Answer: D · After about 6–8 weeks
Why this is the answer
Levothyroxine has a half-life of about a week, so it takes several weeks to reach a new steady state. TSH is usually rechecked about 6–8 weeks after a dose change.
Answer
D · After about 6–8 weeks
4.Med-surg: neuro, endocrine & renal
Answer: C · A pseudo-relapse caused by infection
Why this is the answer
Infection and fever can temporarily worsen existing MS symptoms without new damage (a pseudo-relapse). The infection, here probably a UTI, is treated first. Steroids for a true relapse are considered only if the infection is excluded.
Answer
C · A pseudo-relapse caused by infection
5.Med-surg: GI, perioperative & oncology
Answer: C · Check the feet every day and never walk barefoot
Why this is the answer
Peripheral neuropathy and poor circulation mean injuries can go unnoticed. Daily inspection, well-fitting footwear, checking water temperature and regular podiatry help prevent ulcers.
Answer
C · Check the feet every day and never walk barefoot
6.Med-surg: GI, perioperative & oncology
Answer: C · Restore the seal; if that fails in time, change to a moist dressing
Why this is the answer
NPWT needs an airtight seal. If the seal or suction is lost and cannot be restored promptly (many guidelines say within about 2 hours), the foam is removed and replaced with a standard dressing to reduce infection risk. Manufacturer and local guidance define the safe interval.
Answer
C · Restore the seal; if that fails in time, change to a moist dressing
7.Clinical nursing
Answer: D · Peritonitis
Why this is the answer
Peritonitis, often from perforation, causes guarding, rigidity and pain worsened by movement. It is a surgical emergency.
Answer
D · Peritonitis
8.Clinical nursing
Answer: C · Pericarditis
Why this is the answer
Pericarditis typically causes sharp, positional chest pain relieved by sitting forward, sometimes with a pericardial rub. Viral infection is a common cause.
Answer
C · Pericarditis
9.Lab values & electrolytes
Answer: B · The dye can interfere with dipstick color readings
Why this is the answer
Phenazopyridine is a urinary analgesic dye that turns urine orange-red. It can interfere with color-based dipstick tests, so the laboratory should be told. The color is harmless, but it can stain contact lenses and clothing.Checked against:Urine - abnormal color · MedlinePlus (NIH) (2025)
Answer
B · The dye can interfere with dipstick color readings
10.Lab values & electrolytes
Answer: A · Add dextrose to the IV fluids and continue the insulin
Why this is the answer
The glucose usually falls before the ketoacidosis resolves. Dextrose is added so insulin can continue, clearing ketones without causing hypoglycemia, until the anion gap closes. Stopping insulin too early lets ketoacidosis return.
Answer
A · Add dextrose to the IV fluids and continue the insulin
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 20 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|32 − 40| = 8 mmHg → 0.8 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 − 5·0.8 = 20 mmol/L
Answer
HCO₃⁻ = 20 mmol/L
12.Arterial blood gas interpretation
Answer: AGc = 14 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 139 − (115 + 15) = 9
Correction for albumin
9 + 0.25·(40 − 20) = 14 mmol/L
Answer
AGc = 14 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: QT = 0.36 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
9 small boxes from the start of the QRS to the end of the T wave
Convert
QT = 9 × 0.04 s = 0.36 s
Answer
QT = 0.36 s
A rough rule: at normal rates the QT should be less than half the R–R interval (here R–R = 0.76 s).
14.ECG rhythm strip interpretation
Answer: paced rhythm, failure to capture
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: the pacing spikes are regular (every 0.96 s), but the R–R is not, because a QRS is missing after some spikes.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.16 s and wide after the captured spikes; 2 spikes are not followed by a QRS (no capture).
Interpretation
paced rhythm, failure to capture
Answer
paced rhythm, failure to capture
Failure to capture: the pacemaker fires but the heart does not respond. Textbooks treat it as urgent to report, because the patient may depend on the pacemaker.
15.Prioritization & delegation
Answer: A · Inserting an indwelling urinary catheter in a stable patient
Why this is the answer
Inserting a catheter in a stable patient is a skill commonly within LPN/LVN scope. Admission assessment, initial teaching and starting a transfusion usually stay with the RN. Exact scope differs by state and country.
Answer
A · Inserting an indwelling urinary catheter in a stable patient
16.Prioritization & delegation
Answer: B · Give prescribed opioids and use positioning and a fan to relieve breathlessness
Why this is the answer
In palliative care, opioids are used to relieve breathlessness, along with positioning, a fan and calm reassurance. The aim is comfort, not more investigations.
Answer
B · Give prescribed opioids and use positioning and a fan to relieve breathlessness