Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has pneumonia in the right lung only. In which side-lying position will oxygenation usually be best?
AProne with the head down
BLying on the left side, with the healthy lung down
CLying on the right side, with the affected lung down
DFlat on the back with no pillows
2.Med-surg: cardiovascular & respiratoryHard
After a car crash, a patient is severely breathless with absent breath sounds on the right, a deviated trachea, distended neck veins and BP 76/40 mmHg. What is the immediate management?
ALying the patient flat with the legs raised
BUrgent needle or finger decompression of the right chest
CA chest X-ray to confirm the diagnosis before any treatment
DInsertion of a urinary catheter to monitor output
3.Med-surg: neuro, endocrine & renalMedium
A man starts tamsulosin for BPH. Which teaching point is most important?
AExpect the drug to shrink the prostate within a day
BStand up slowly, because it can make you dizzy
CStop it if the urine stream improves
DTake it with grapefruit juice to make it work better
4.Med-surg: neuro, endocrine & renalHard
During a water deprivation test for suspected diabetes insipidus, the patient loses more than 3% of body weight and becomes hypotensive. What should the nurse do?
AGive desmopressin without a prescription
BContinue the test, because this result is expected
CStop the test and inform the doctor
DGive the patient a large drink and then restart the test
5.Med-surg: GI, perioperative & oncologyMedium
Which is a recognised risk of long-term proton pump inhibitor use?
AHyperkalaemia
BHypomagnesaemia
CHypernatraemia
DHypercalcaemia
6.Med-surg: GI, perioperative & oncologyHard
After a high-voltage electrical injury, a patient's urine is dark red-brown. What does this suggest and what is the usual aim?
ANormal concentrated urine; restrict fluids
BA urinary infection; send a sample and wait for the result
CMyoglobin from muscle damage; a higher urine output target
DBleeding from the bladder; stop all fluids
7.Clinical nursingMedium
Which assessment best detects compartment syndrome after a fractured leg is put in a cast?
AMild itching under the cast
BA strong pulse in the foot
CA warm, pink foot
DPain out of proportion to the injury, especially on passive stretch
8.Clinical nursingHard
A nurse phones a doctor about a deteriorating patient using SBAR. Which statement belongs in the "R" section?
A"He was admitted three days ago with pneumonia."
B"Please review him within the next 15 minutes."
C"His blood pressure is 85/50 and he is confused."
D"I am calling about Mr Smith, who is breathless."
9.Lab values & electrolytesMedium
A patient with schizophrenia is starting clozapine. Which laboratory value must be monitored regularly?
ASerum lithium level
BInternational normalized ratio
CAbsolute neutrophil count
DSerum amylase
10.Lab values & electrolytesHard
A patient with long-standing rheumatoid arthritis has a hemoglobin of 10.5 g/dL (105 g/L), a low serum iron, a low total iron-binding capacity (TIBC) and a high-normal ferritin. Which condition fits best?
AAnemia of chronic disease (inflammation)
BIron-deficiency anemia
CAcute blood loss anemia
DVitamin B12 deficiency anemia
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 144 mmol/L, glucose 28.6 mmol/L and urea 12.5 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 144 mmol/Lglucose 28.6 mmol/Lurea 12.5 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.20, PaCO₂ 72 mmHg (9.6 kPa), HCO₃⁻ 27 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.20PaCO₂ 72 mmHg (9.6 kPa)HCO₃⁻ 27 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2first-degree AV block
3normal sinus rhythm
4sinus tachycardia
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2second-degree AV block type II
3junctional rhythm
4first-degree AV block
15.Prioritization & delegationMedium
A patient uses patient-controlled analgesia (PCA) after surgery. Which statement by a family member shows a need for further teaching?
A“Only she should press the button when she needs pain relief.”
B“I will press the button for her while she is asleep so she stays comfortable.”
C“The pump has limits set by the nurse so she cannot get too much at once.”
D“I will tell the nurse if she becomes very sleepy or hard to wake.”
16.Prioritization & delegationHard
Weeks after a kidney transplant, a patient has a fever, less urine and tenderness over the new kidney. What should the nurse suspect?
ANormal healing of the transplant
BDehydration from drinking too much
CRejection of the transplant
DA side effect of eating salty food
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Lying on the left side, with the healthy lung down
Why this is the answer
Blood flow goes preferentially to the dependent lung. Placing the healthy lung down matches more blood to the well-ventilated lung, improving oxygenation ("good lung down"). Exceptions include a lung abscess or bleeding, when the affected lung is placed down to protect the healthy one.
Answer
B · Lying on the left side, with the healthy lung down
2.Med-surg: cardiovascular & respiratory
Answer: B · Urgent needle or finger decompression of the right chest
Why this is the answer
These signs indicate a tension pneumothorax, which causes obstructive shock. It is decompressed immediately (needle or finger thoracostomy) without waiting for an X-ray, followed by a chest drain. The nurse gives high-flow oxygen and calls for senior help.
Answer
B · Urgent needle or finger decompression of the right chest
3.Med-surg: neuro, endocrine & renal
Answer: B · Stand up slowly, because it can make you dizzy
Why this is the answer
Tamsulosin relaxes smooth muscle in the prostate and bladder neck, improving urine flow within days. It can cause postural hypotension and dizziness, especially after the first dose, so patients rise slowly.
Answer
B · Stand up slowly, because it can make you dizzy
4.Med-surg: neuro, endocrine & renal
Answer: C · Stop the test and inform the doctor
Why this is the answer
In DI, the patient keeps passing dilute urine despite fluid restriction and can become dangerously dehydrated. Significant weight loss, hypotension or a high sodium are reasons to stop the test and get medical review.
Answer
C · Stop the test and inform the doctor
5.Med-surg: GI, perioperative & oncology
Answer: B · Hypomagnesaemia
Why this is the answer
Long-term PPIs are linked with low magnesium, C. difficile infection, fractures and B12 deficiency. The need for continuing treatment should be reviewed regularly.
Answer
B · Hypomagnesaemia
6.Med-surg: GI, perioperative & oncology
Answer: C · Myoglobin from muscle damage; a higher urine output target
Why this is the answer
Electrical injury can cause extensive muscle breakdown, releasing myoglobin that can damage the kidneys. A higher urine output target is set, with fluids titrated and creatine kinase and kidney function monitored.
Answer
C · Myoglobin from muscle damage; a higher urine output target
7.Clinical nursing
Answer: D · Pain out of proportion to the injury, especially on passive stretch
Why this is the answer
Increasing pain that is not relieved by analgesia and worsens with passive stretching is the earliest sign. Pallor, numbness and absent pulses are late signs.
Answer
D · Pain out of proportion to the injury, especially on passive stretch
8.Clinical nursing
Answer: B · "Please review him within the next 15 minutes."
Why this is the answer
In SBAR, R is the recommendation or request, such as a review within a time frame. The other statements belong to Assessment, Background and Situation.
Answer
B · "Please review him within the next 15 minutes."
9.Lab values & electrolytes
Answer: C · Absolute neutrophil count
Why this is the answer
Clozapine can cause severe neutropenia (agranulocytosis), so the ANC is checked before starting and regularly during treatment. A sore throat, fever or other sign of infection must be reported at once.
Answer
C · Absolute neutrophil count
10.Lab values & electrolytes
Answer: A · Anemia of chronic disease (inflammation)
Why this is the answer
In chronic inflammation, iron is trapped in stores, so serum iron is low but ferritin is normal or high and TIBC is low. In iron deficiency, ferritin is low and TIBC is high. Iron supplements help iron deficiency much more than anemia of chronic disease.Checked against:Ferritin Blood Test · MedlinePlus (NIH) (2025); Serum iron test · MedlinePlus (NIH) (2026)
Answer
A · Anemia of chronic disease (inflammation)
11.Arterial blood gas interpretation
Answer: Osm = 329 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·144 + 28.6 + 12.5 = 329.1 ≈ 329 mOsm/kg
Answer
Osm = 329 mOsm/kg
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·3.2 = 27.2 mmol/L
chronic: 24 + 3.5·3.2 = 35.2 mmol/L
Compare
measured: 27 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: sinus bradycardia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 30 small boxes, 1500 ÷ 30 ≈ 50 per minute.
2. Rhythm: regular, every R–R is 1.20 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
sinus bradycardia
Answer
sinus bradycardia
14.ECG rhythm strip interpretation
Answer: third-degree (complete) AV block
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: R–R = 53 small boxes, 1500 ÷ 53 ≈ 28 per minute.
2. Rhythm: R–R regular (2.12 s) and P–P regular (0.64 s), but the two are independent.
3. P waves: upright and regular at 94 per minute, but not linked to the QRS complexes; some hide in a QRS or a T wave.
4. PR interval: varies from beat to beat; there is no fixed relation.
5. QRS: 0.16 s, wide (0.12 s or more).
Interpretation
third-degree (complete) AV block
Answer
third-degree (complete) AV block
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: B · “I will press the button for her while she is asleep so she stays comfortable.”
Why this is the answer
PCA is safe because a sleepy patient cannot press the button. If someone else presses it, the patient can receive too much opioid and develop respiratory depression.
Answer
B · “I will press the button for her while she is asleep so she stays comfortable.”
16.Prioritization & delegation
Answer: C · Rejection of the transplant
Why this is the answer
Fever, falling urine output and graft tenderness are signs of possible rejection. The nurse reports promptly, because early treatment can save the kidney.