Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Before compression therapy is applied for a venous leg ulcer, which assessment is essential?
AA full blood count and CRP
BA wound swab for culture and sensitivity
CA chest X-ray and ECG
DAn ankle–brachial pressure index (ABPI)
2.Med-surg: cardiovascular & respiratoryHard
A patient with a valid, documented do-not-attempt-CPR decision (DNACPR in the UK, DNR or DNAR in the US) is found in cardiac arrest. What should the nurse do?
ANot start CPR, call for support, and provide dignity and comfort
BCall the arrest team and let them decide whether to resuscitate
CStart CPR but use only chest compressions
DStart full CPR because the patient's family is not present
3.Med-surg: neuro, endocrine & renalMedium
How does bladder training help urge incontinence?
AThe time between voids is slowly increased
BA catheter is used every night
CThe patient drinks as little as possible
DThe patient goes to the toilet every 15 minutes
4.Med-surg: neuro, endocrine & renalHard
Why may HbA1c be unreliable in a patient with haemolytic anaemia or a recent large blood transfusion?
ABlood transfusions contain large amounts of glucose
BIt depends on how long red blood cells survive in the blood
CThe test only measures the glucose in the plasma, not in the cells
DAnaemia always makes the HbA1c very high
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps a person with diabetes prevent foot ulcers?
ACheck the feet every day and never walk barefoot
BCut corns off at home with a sharp blade
CWear tight shoes to support the ankles
DSoak the feet in very hot water every evening
6.Med-surg: GI, perioperative & oncologyHard
Two hours after a meal, a patient who had a gastrectomy becomes shaky, sweaty and confused. What is the most likely cause and first action?
AVitamin B12 deficiency; give an injection now
BEarly dumping from fluid shifts; give a large drink of water
CLate dumping with low blood glucose; check capillary glucose
DAn anastomotic leak; insert a nasogastric tube at once
7.Clinical nursingMedium
Why must a patient with a new coronary stent not stop their antiplatelet medicines without specialist advice?
AThe stent will dissolve if the drugs are stopped before the course ends
BStopping causes severe low blood pressure
CStopping early greatly increases the risk of a clot forming in the stent
DStopping causes immediate kidney failure
8.Clinical nursingHard
After a head injury, a patient has clear fluid leaking from the nose. What does this most likely suggest?
AAllergic rhinitis triggered by the hospital environment
BAcute sinusitis
CA normal and harmless response to head trauma
DA base-of-skull fracture with a cerebrospinal fluid leak
9.Lab values & electrolytesMedium
A patient starts high-dose prednisone. Which laboratory change should the nurse expect?
AA rise in serum potassium
BA rise in blood glucose
CA fall in the white cell count
DA fall in serum sodium
10.Lab values & electrolytesHard
A patient with blood pressure that is hard to control has a potassium of 2.9 mEq/L, a sodium of 144 mEq/L and a raised serum bicarbonate, without taking a diuretic. Which condition is most likely?
ASyndrome of inappropriate ADH
BPrimary hyperaldosteronism
CPrimary adrenal insufficiency
DCentral diabetes insipidus
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 80 mmHg (10.7 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1ventricular bigeminy
2sinus rhythm with PVCs
3atrial fibrillation
4sinus arrhythmia
14.ECG rhythm strip interpretationHard
This lead II strip shows second-degree AV block type I (Wenckebach). How many P waves per group are there, counting the non-conducted one (the n of an n:(n − 1) block)?
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
P waves per group =
15.Prioritization & delegationMedium
An adult patient eating in the dayroom suddenly clutches their throat and cannot speak, breathe or cough. What should the nurse do first?
ADo a blind finger sweep of the mouth
BCall for help and give back blows and abdominal thrusts
CGive the patient a glass of water to wash the food down
DWait to see whether the patient can cough it out
16.Prioritization & delegationHard
After the RN taught a patient to inject insulin, an LPN/LVN reports that the patient still cannot draw up the dose correctly. What should happen next?
AThe LPN/LVN writes a new teaching plan and evaluates it at the end of the shift
BThe patient is discharged with a leaflet to read at home
CThe nursing assistant shows the patient again at lunch
DThe RN reassesses the patient’s learning needs and adjusts the teaching
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · An ankle–brachial pressure index (ABPI)
Why this is the answer
Compression helps venous return but can cause tissue necrosis if the arterial supply is inadequate. The ABPI compares ankle and arm systolic pressures; a value below about 0.8 (or above about 1.3, suggesting calcified vessels) needs specialist review before compression.
Answer
D · An ankle–brachial pressure index (ABPI)
2.Med-surg: cardiovascular & respiratory
Answer: A · Not start CPR, call for support, and provide dignity and comfort
Why this is the answer
A valid do-not-attempt-CPR decision means CPR is not attempted. Other appropriate care continues, the senior team and family are informed and the patient is cared for with dignity. Nurses should check that the decision is valid and applies to the situation.
Answer
A · Not start CPR, call for support, and provide dignity and comfort
3.Med-surg: neuro, endocrine & renal
Answer: A · The time between voids is slowly increased
Why this is the answer
In bladder training, the patient follows a schedule and gradually lengthens the time between voids while using urge-suppression techniques. Over weeks, bladder capacity and control improve. Very low fluid intake makes urine concentrated and irritating.
Answer
A · The time between voids is slowly increased
4.Med-surg: neuro, endocrine & renal
Answer: B · It depends on how long red blood cells survive in the blood
Why this is the answer
HbA1c reflects glucose exposure over the lifespan of red cells. If red cells are destroyed early, or donor cells are added, the result may not match true average glucose. Glucose monitoring or other tests may be used instead.
Answer
B · It depends on how long red blood cells survive in the blood
5.Med-surg: GI, perioperative & oncology
Answer: A · Check the feet every day and never walk barefoot
Why this is the answer
Peripheral neuropathy and poor circulation mean injuries can go unnoticed. Daily inspection, well-fitting footwear, checking water temperature and regular podiatry help prevent ulcers.
Answer
A · Check the feet every day and never walk barefoot
6.Med-surg: GI, perioperative & oncology
Answer: C · Late dumping with low blood glucose; check capillary glucose
Why this is the answer
In late dumping, rapid sugar absorption triggers a large insulin release, followed by reactive hypoglycaemia 1–3 hours after eating. The nurse checks glucose and treats hypoglycaemia; dietary changes help prevent it.
Answer
C · Late dumping with low blood glucose; check capillary glucose
7.Clinical nursing
Answer: C · Stopping early greatly increases the risk of a clot forming in the stent
Why this is the answer
Dual antiplatelet therapy prevents stent thrombosis while the stent becomes covered by the artery lining. Stopping early can cause a sudden myocardial infarction.
Answer
C · Stopping early greatly increases the risk of a clot forming in the stent
8.Clinical nursing
Answer: D · A base-of-skull fracture with a cerebrospinal fluid leak
Why this is the answer
Clear fluid from the nose or ear after head injury suggests a CSF leak from a skull base fracture, with a risk of meningitis. Nasal tubes and nose-blowing should be avoided and the patient reviewed urgently.
Answer
D · A base-of-skull fracture with a cerebrospinal fluid leak
9.Lab values & electrolytes
Answer: B · A rise in blood glucose
Why this is the answer
Glucocorticoids raise blood glucose by increasing glucose production and reducing insulin sensitivity. They also tend to lower potassium, retain sodium and raise the white cell count by releasing neutrophils into the blood.Checked against:Blood Glucose Test · MedlinePlus (NIH) (2024)
Answer
B · A rise in blood glucose
10.Lab values & electrolytes
Answer: B · Primary hyperaldosteronism
Why this is the answer
Excess aldosterone causes sodium and water retention (hypertension), potassium loss (hypokalemia) and hydrogen ion loss (metabolic alkalosis). Adrenal insufficiency causes the opposite pattern, with low sodium and high potassium.Checked against:Primary and secondary hyperaldosteronism · MedlinePlus (NIH) (2025); Alkalosis · StatPearls (NCBI Bookshelf) (2024)
Answer
B · Primary hyperaldosteronism
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 38 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|80 − 40| = 40 mmHg → 4 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·4 = 38 mmol/L
Answer
HCO₃⁻ = 38 mmol/L
12.Arterial blood gas interpretation
Answer: AGc = 14 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 144 − (115 + 20) = 9
Correction for albumin
9 + 0.25·(40 − 20) = 14 mmol/L
Answer
AGc = 14 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: ventricular bigeminy
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 7 QRS complexes in 6 s, × 10 = 70 per minute.
2. Rhythm: regularly irregular, a short and a long R–R alternate (0.50 s and 1.18 s).
3. P waves: upright before every narrow QRS; none before the early wide beats.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s in the sinus beats; the early beats are wide (0.16 s) and bizarre, with the T wave pointing the other way.
Interpretation
ventricular bigeminy
Answer
ventricular bigeminy
14.ECG rhythm strip interpretation
Answer: P waves per group = 4
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
March out the P waves
P–P = 1.00 s, regular; one P wave in every 4 is not conducted
PR in each group
PR₁ = 0.16 s, PR₂ = 0.28 s, PR₃ = 0.34 s
Answer
P waves per group = 4
A 4:3 Wenckebach block.
15.Prioritization & delegation
Answer: B · Call for help and give back blows and abdominal thrusts
Why this is the answer
An adult who cannot speak, breathe or cough has a severe airway obstruction. Resuscitation guidelines such as those of the European Resuscitation Council recommend up to 5 back blows followed by up to 5 abdominal thrusts, repeated until the object clears; some guidelines start with abdominal thrusts. If the patient becomes unresponsive, CPR is started. A blind finger sweep can push the object further in.
Answer
B · Call for help and give back blows and abdominal thrusts
16.Prioritization & delegation
Answer: D · The RN reassesses the patient’s learning needs and adjusts the teaching
Why this is the answer
Evaluating learning and changing the teaching plan belong to the RN. The LPN/LVN can reinforce teaching, but a teaching plan that is not working needs RN reassessment.
Answer
D · The RN reassesses the patient’s learning needs and adjusts the teaching