Medical-Surgical Nursing: cram pack

Formula sheets, the key method steps for every topic and 16 practice problems, with full solutions at the back.

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1Formulas and methods

Med-surg: cardiovascular & respiratory

Method

  1. Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
  2. Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
  3. Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
  4. Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
  5. Choose the safe first action, then escalate and reassess.

Med-surg: neuro, endocrine & renal

Method

  1. Check the glucose in every patient with new confusion, weakness or a seizure.
  2. Use the level of consciousness as the earliest warning of brain trouble; pupils and Cushing’s triad come late.
  3. For diabetes emergencies, separate DKA (ketones, acidosis) from HHS (very high osmolality, dehydration); give fluids first.
  4. For sodium and water, decide whether ADH is in excess (SIADH) or missing (DI), and correct chronic changes slowly.
  5. For kidney problems, sort the cause into pre-renal, intrinsic or post-renal, and watch potassium and fluid.

Med-surg: GI, perioperative & oncology

Method

  1. Ask what could be hidden: internal bleeding, infection without fever, hypoventilation behind a normal SpO₂.
  2. Use the timing after surgery to narrow the complications: bleeding in hours, chest problems in days, wound and leak problems later.
  3. For pain, assess, treat with multimodal analgesia, reassess, and monitor sedation with every opioid.
  4. For cancer patients, treat any illness during the nadir as neutropenic sepsis and know the oncological emergencies.
  5. For burns, count only partial- and full-thickness areas, start the Parkland clock at the time of the burn and titrate to urine output.

Lab values & electrolytes

Method

  1. Compare the value with the laboratory’s own reference range, then with the patient’s baseline and trend.
  2. Check the sample: hemolysis, a delay, or blood drawn near an IV can give false results.
  3. Link the value to its typical signs and to the drugs and conditions that cause it.
  4. Look for interactions: low potassium or magnesium increases digoxin toxicity; dehydration raises lithium.
  5. Act on the patient: assess, hold a drug if the level is unsafe, read back critical values and inform the prescriber.

Arterial blood gas interpretation

Normal ranges
pH 7.35–7.45, PaCO₂ 35–45 mmHg (4.7–6.0 kPa), HCO₃⁻ 22–26 mmol/L
ROME
Respiratory: PaCO₂ opposite to pH; Metabolic: HCO₃⁻ equal to pH
Winter’s formula
PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2
Metabolic alkalosis
PaCO₂ ≈ 0.7·HCO₃⁻ + 21
Anion gap
AG = Na⁺ − (Cl⁻ + HCO₃⁻) ≈ 8–12
Albumin-corrected gap
AG + 2.5·(4.0 − alb g/dL) = AG + 0.25·(40 − alb g/L)
Delta ratio
(AG − 12)/(24 − HCO₃⁻)
P/F ratio
PaO₂/FiO₂
Alveolar gas equation
PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8
Serum osmolality
2·Na⁺ + glucose + urea (2·Na⁺ + glucose/18 + BUN/2.8)

Method

  1. Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
  2. Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
  3. Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
  4. In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
  5. Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.

ECG rhythm strip interpretation

Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)

Method

  1. Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
  2. Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
  3. P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
  4. PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
  5. QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.

Prioritization & delegation

Method

  1. Ask what will harm the patient soonest if nothing is done.
  2. Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
  3. Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
  4. Assess before you act unless it is an emergency; then choose the step the others depend on.
  5. For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.

2Practice problems

1.Med-surg: cardiovascular & respiratoryMedium

A patient with a mechanical heart valve asks to switch from warfarin to apixaban. What is the correct response?

  1. AAny anticoagulant works equally well once the valve is in place
  2. BDirect oral anticoagulants are not used for mechanical valves
  3. CAspirin alone can replace warfarin once the valve has healed
  4. DMechanical valves do not need anticoagulation after the first month
2.Med-surg: cardiovascular & respiratoryHard

Minutes after an IV antibiotic is started, a patient has wheeze, swollen lips, a rash and BP 78/44 mmHg. The infusion has been stopped and help called. What is the next priority?

  1. AGive intramuscular adrenaline (epinephrine)
  2. BGive a nebulised salbutamol dose only
  3. CRestart the infusion at a slower rate
  4. DGive an oral antihistamine tablet and observe for an hour
3.Med-surg: neuro, endocrine & renalMedium

A patient with Alzheimer's disease starts donepezil. Which side effects should the nurse look for?

  1. AWeight gain, high glucose and swollen ankles
  2. BDry mouth, constipation and a fast heart rate
  3. CNausea, diarrhoea and a slow heart rate
  4. DA persistent dry cough and a raised potassium
4.Med-surg: neuro, endocrine & renalHard

A patient with gastroparesis has hypos soon after their meal-time insulin, then high glucose several hours later. What is the best explanation?

  1. AThe meter gives false results for several hours after every meal
  2. BFood is absorbed slowly, so the insulin peaks before the glucose rises
  3. CThe insulin has gone off and needs replacing
  4. DThe patient is secretly eating sweets between meals
5.Med-surg: GI, perioperative & oncologyMedium

Which electrolyte problem can occur in severe acute pancreatitis?

  1. AHyperkalaemia
  2. BHypocalcaemia
  3. CHypernatraemia
  4. DHypercalcaemia
6.Med-surg: GI, perioperative & oncologyHard

Which preoperative blood result should the nurse report to the team before elective surgery?

  1. AHaemoglobin 138 g/L (13.8 g/dL) in a man
  2. BFasting glucose 5.4 mmol/L (97 mg/dL)
  3. CPotassium 2.9 mmol/L
  4. DSodium 139 mmol/L
7.Clinical nursingMedium

Which group of symptoms suggests hypercalcaemia?

  1. AWeight gain, feeling cold and a slow pulse
  2. BThirst, constipation, confusion and abdominal pain
  3. CTingling lips, muscle cramps and spasms of the hands and feet
  4. DSweating, tremor and sudden hunger
8.Clinical nursingHard

A patient with severe ulcerative colitis develops abdominal distension, fever and tachycardia, and the number of stools falls. What complication should be suspected?

  1. ACoeliac disease
  2. BConstipation from dehydration
  3. CToxic megacolon
  4. DRecovery from the colitis
9.Lab values & electrolytesMedium

A patient on a heparin infusion has an aPTT of 110 seconds; the protocol target is 1.5–2.5 times the control of 30 seconds. What should the nurse do?

  1. AFollow the heparin protocol, check for bleeding and inform the provider
  2. BIncrease the infusion rate, because the result is above the target range
  3. CContinue unchanged and repeat the aPTT the next morning
  4. DGive vitamin K as prescribed and continue the infusion
10.Lab values & electrolytesHard

Which cerebrospinal fluid (CSF) pattern most strongly suggests bacterial meningitis?

  1. AClear fluid, normal glucose, normal protein, no white cells
  2. BCloudy fluid, low glucose, high protein, many neutrophils
  3. CClear fluid, high glucose, low protein, many red cells
  4. DClear fluid, normal glucose, mildly raised protein, lymphocytes
11.Arterial blood gas interpretationMedium

A practice gas shows PaCO₂ 49 mmHg (6.5 kPa). Use the rule that in acute respiratory acidosis HCO₃⁻ rises by 1 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.

PaCO₂ 49 mmHg (6.5 kPa)baseline: 40 mmHg, 24 mmol/L
HCO₃⁻ = mmol/L
12.Arterial blood gas interpretationHard

At sea level, a practice gas taken on 30% oxygen shows PaO₂ 79 mmHg (10.5 kPa) and PaCO₂ 45 mmHg (6.0 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.

FiO₂ 30%PaO₂ 79 mmHg (10.5 kPa)PaCO₂ 45 mmHg (6.0 kPa)
A–a gradient = mmHg
13.ECG rhythm strip interpretationMedium
II25 mm/s · 10 mm/mV

Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.

lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
II25 mm/s · 10 mm/mVsynchronised cardioversionimmediate defibrillationCPR (non-shockable rhythm)transcutaneous pacing

A patient without a palpable pulse has this organised rhythm on the monitor (pulseless electrical activity). Which treatment do adult resuscitation guidelines name for it? Click your answer.

lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
  1. 1synchronised cardioversion
  2. 2immediate defibrillation
  3. 3CPR (non-shockable rhythm)
  4. 4transcutaneous pacing
15.Prioritization & delegationMedium

Using the Emergency Severity Index, which level fits a 70-year-old with chest pressure that suggests a heart attack, but normal vital signs?

  1. ALevel 5
  2. BLevel 1
  3. CLevel 4
  4. DLevel 2
16.Prioritization & delegationHard

Which patient with cirrhosis should the nurse see first?

  1. ALarge ascites that is unchanged from yesterday
  2. BLong-standing jaundice and itchy skin, asking for cream
  3. CVomiting bright red blood, heart rate 120/min
  4. DWants to talk about stopping drinking alcohol for good

3Solutions

1.Med-surg: cardiovascular & respiratory

Answer: B · Direct oral anticoagulants are not used for mechanical valves

Why this is the answer

Mechanical valves need lifelong anticoagulation with a vitamin K antagonist such as warfarin. Direct oral anticoagulants caused more clots and bleeding in mechanical valve patients and are contraindicated. Biological valves usually need only short-term anticoagulation.

Answer

B · Direct oral anticoagulants are not used for mechanical valves
2.Med-surg: cardiovascular & respiratory

Answer: A · Give intramuscular adrenaline (epinephrine)

Why this is the answer

Anaphylaxis is treated first with intramuscular adrenaline into the anterolateral thigh, repeated after about 5 minutes if needed. It reverses bronchospasm, vasodilation and swelling. Oxygen, IV fluids and lying the patient flat (or sitting if breathing is easier) follow. Antihistamines and steroids are not first-line.

Answer

A · Give intramuscular adrenaline (epinephrine)
3.Med-surg: neuro, endocrine & renal

Answer: C · Nausea, diarrhoea and a slow heart rate

Why this is the answer

Donepezil is a cholinesterase inhibitor. Raised acetylcholine can cause nausea, vomiting, diarrhoea, vivid dreams and bradycardia, which can lead to dizziness or fainting.

Answer

C · Nausea, diarrhoea and a slow heart rate
4.Med-surg: neuro, endocrine & renal

Answer: B · Food is absorbed slowly, so the insulin peaks before the glucose rises

Why this is the answer

Delayed gastric emptying means carbohydrate reaches the blood later than expected. The insulin acts too early, causing a hypo, and glucose rises later. The prescriber may change the timing, for example giving the insulin after the meal.

Answer

B · Food is absorbed slowly, so the insulin peaks before the glucose rises
5.Med-surg: GI, perioperative & oncology

Answer: B · Hypocalcaemia

Why this is the answer

Fat necrosis releases fatty acids that bind calcium (saponification), lowering serum calcium. Hypocalcaemia is a marker of severity and can cause tetany and arrhythmias. Hypercalcaemia, on the other hand, can be a cause of pancreatitis.

Answer

B · Hypocalcaemia
6.Med-surg: GI, perioperative & oncology

Answer: C · Potassium 2.9 mmol/L

Why this is the answer

Normal potassium is about 3.5–5.0 mmol/L. Hypokalaemia increases the risk of arrhythmias during anaesthesia and needs correction before elective surgery. The other results are within normal ranges.

Answer

C · Potassium 2.9 mmol/L
7.Clinical nursing

Answer: B · Thirst, constipation, confusion and abdominal pain

Why this is the answer

High calcium causes polyuria and thirst, constipation, abdominal pain, kidney stones and confusion. Tingling and cramps suggest low calcium instead.

Answer

B · Thirst, constipation, confusion and abdominal pain
8.Clinical nursing

Answer: C · Toxic megacolon

Why this is the answer

Toxic megacolon is acute dilatation of the inflamed colon with systemic toxicity, and it can perforate. Reduced stool frequency with worsening distension is a warning sign needing urgent surgical review.

Answer

C · Toxic megacolon
9.Lab values & electrolytes

Answer: A · Follow the heparin protocol, check for bleeding and inform the provider

Why this is the answer

110 s is well above the target of about 45–75 s, so the bleeding risk is high. The nurse follows the heparin protocol, assesses for bleeding and informs the provider. Protamine is the reversal agent for heparin; vitamin K reverses warfarin.Checked against: Partial Thromboplastin Time (PTT) Test · MedlinePlus (NIH) (2026)

Answer

A · Follow the heparin protocol, check for bleeding and inform the provider
10.Lab values & electrolytes

Answer: B · Cloudy fluid, low glucose, high protein, many neutrophils

Why this is the answer

Bacterial meningitis typically gives cloudy CSF with many neutrophils, high protein and low glucose, because bacteria and white cells use glucose. Viral meningitis usually shows lymphocytes with a normal glucose; option C is normal CSF.Checked against: CSF glucose test · MedlinePlus (NIH) (2025); CSF cell count · MedlinePlus (NIH) (2025); CSF total protein · MedlinePlus (NIH) (2025)

Answer

B · Cloudy fluid, low glucose, high protein, many neutrophils
11.Arterial blood gas interpretation

Answer: HCO₃⁻ = 24.9 mmol/L

Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.

Change in PaCO₂

|49 − 40| = 9 mmHg → 0.9 × 10 mmHg

Expected HCO₃⁻

HCO₃⁻ = 24 + 1·0.9 = 24.9 mmol/L

Answer

HCO₃⁻ = 24.9 mmol/L
12.Arterial blood gas interpretation

Answer: A–a gradient = 78.65 mmHg

Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.

Alveolar oxygen

PAO₂ = 0.3·713 − 45/0.8 = 213.9 − 56.25 = 157.7 mmHg

Gradient

A–a = 157.7 − 79 = 78.65 mmHg

Answer

A–a gradient = 78.65 mmHg
13.ECG rhythm strip interpretation

Answer: QTc = 0.48 s

QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.

Measure

QT = 11.5 × 0.04 = 0.46 s
RR = 23 × 0.04 = 0.92 s

Bazett’s formula

QTc = 0.46/√0.92 = 0.46/0.9592 = 0.48 s

Answer

QTc = 0.48 s

Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (480 ms)

14.ECG rhythm strip interpretation

Answer: CPR (non-shockable rhythm)

Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.

What the strip shows

1. Rate: R–R = 13 small boxes, 1500 ÷ 13 ≈ 115 per minute.
2. Rhythm: regular, every R–R is 0.52 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
sinus tachycardia

What the patient shows

no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm

Answer

CPR (non-shockable rhythm)

Answer

CPR (non-shockable rhythm)

PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.

15.Prioritization & delegation

Answer: D · Level 2

Why this is the answer

Possible acute coronary syndrome is a high-risk situation, so the patient is ESI level 2 and should be seen very soon. Level 1 is kept for patients who need an immediate life-saving intervention.

Answer

D · Level 2
16.Prioritization & delegation

Answer: C · Vomiting bright red blood, heart rate 120/min

Why this is the answer

Vomiting blood with a fast pulse suggests bleeding esophageal varices, which can quickly be fatal. The other findings are chronic or stable.

Answer

C · Vomiting bright red blood, heart rate 120/min

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