Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has exercise-induced asthma. Which advice is most appropriate?
AExercise only in cold, dry air to toughen the airways
BUse the reliever inhaler shortly before exercise and warm up
CTake a beta-blocker before exercise
DAvoid all forms of exercise permanently to prevent attacks
2.Med-surg: cardiovascular & respiratoryHard
A 74-year-old man with a known abdominal aortic aneurysm suddenly has severe back and abdominal pain. His heart rate is 128/min and BP 82/50 mmHg. What is the priority?
ACall for emergency help and prepare for urgent vascular surgery
BGive oral analgesia and reassess the pain in an hour
CEncourage him to walk to ease the back pain
DArrange a routine outpatient ultrasound scan of the aneurysm
3.Med-surg: neuro, endocrine & renalMedium
Why do patients with CKD often take phosphate binders with meals?
AThey bind food phosphate that the kidneys cannot excrete
BThey replace the missing hormone erythropoietin
CThey lower blood potassium by binding it in the gut
DThey increase the absorption of phosphate from food in the gut
4.Med-surg: neuro, endocrine & renalHard
A nurse teaches a woman with recurrent UTIs. Which statement shows a need for further teaching?
A"I will pass urine soon after sex."
B"I will wipe from front to back."
C"I will hold my urine for as long as I can."
D"I will drink enough fluids during the day."
5.Med-surg: GI, perioperative & oncologyMedium
Which check is routinely made for a patient with a burn wound?
AMeasles vaccination status
BVisual acuity in both eyes
CBlood group of the next of kin
DTetanus immunisation status
6.Med-surg: GI, perioperative & oncologyHard
Which patient has the highest risk of postoperative nausea and vomiting?
AA smoker who has never had nausea after surgery
BA male smoker having a short procedure without opioids
CA man with no history of nausea having local anaesthetic only
DA non-smoking woman with motion sickness who will need opioids
7.Clinical nursingMedium
Which statement about storing insulin is correct?
AInsulin never expires once opened
BInsulin should be kept in direct sunlight
CUnopened insulin is kept in the fridge and must not be frozen
DAll insulin should be stored in the freezer to keep it fresh
8.Clinical nursingHard
Soon after starting chemotherapy for a high-grade lymphoma, a patient has rising potassium, phosphate and uric acid with falling urine output. What is the most likely cause?
AAdrenal insufficiency
BSyndrome of inappropriate ADH secretion
CTumour lysis syndrome
DRefeeding syndrome
9.Lab values & electrolytesMedium
A patient starts lisinopril (an ACE inhibitor). Which laboratory values should the nurse expect to be monitored?
APotassium and creatinine
BCalcium and phosphate
CALT and bilirubin
DTSH and free T4
10.Lab values & electrolytesHard
A health care worker's hepatitis B tests show: HBsAg negative, anti-HBs positive, anti-HBc positive. What does this mean?
ANot immune and never exposed to the virus
BPast infection that has resolved, with immunity
CImmunity from vaccination only, never infected
DCurrent chronic hepatitis B infection
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.43, PaCO₂ 22 mmHg (2.9 kPa) and HCO₃⁻ 14 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.43PaCO₂ 22 mmHg (2.9 kPa)HCO₃⁻ 14 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.33, PaCO₂ 35 mmHg (4.7 kPa), HCO₃⁻ 18 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.33PaCO₂ 35 mmHg (4.7 kPa)HCO₃⁻ 18 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus rhythm with wide QRS
2dual-chamber (AV) paced rhythm
3idioventricular rhythm
4junctional rhythm
15.Prioritization & delegationMedium
During a blood transfusion, a patient develops chills, back pain and a fever. What is the nurse’s first action?
ASlow the transfusion and recheck in an hour
BFinish the unit quickly through a pressure bag so that the reaction does not last long
CStop the transfusion and keep the IV open with normal saline via new tubing
DGive an antipyretic and continue the transfusion
16.Prioritization & delegationHard
A patient on airborne precautions for suspected tuberculosis must go to the radiology department. What should the patient wear during transport?
AGloves and a gown only
BA surgical mask
CNothing, if the trip is short
DA fit-tested N95 respirator
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Use the reliever inhaler shortly before exercise and warm up
Why this is the answer
A short-acting bronchodilator taken shortly before exercise, a gradual warm-up and covering the mouth in cold air help prevent symptoms. Frequent exercise symptoms may mean asthma is poorly controlled and preventer treatment needs review.
Answer
B · Use the reliever inhaler shortly before exercise and warm up
2.Med-surg: cardiovascular & respiratory
Answer: A · Call for emergency help and prepare for urgent vascular surgery
Why this is the answer
Sudden abdominal or back pain with hypotension in a patient with an AAA suggests rupture, which is often fatal without urgent repair. The team is called at once, large-bore IV access and blood are arranged, and the patient goes to theatre. Fluid may be limited so the blood pressure is not pushed high (permissive hypotension), as directed by the team.
Answer
A · Call for emergency help and prepare for urgent vascular surgery
3.Med-surg: neuro, endocrine & renal
Answer: A · They bind food phosphate that the kidneys cannot excrete
Why this is the answer
In CKD, phosphate retention leads to secondary hyperparathyroidism, renal bone disease and vascular calcification. Phosphate binders taken with meals bind dietary phosphate in the gut. Dietary phosphate is also limited.
Answer
A · They bind food phosphate that the kidneys cannot excrete
4.Med-surg: neuro, endocrine & renal
Answer: C · "I will hold my urine for as long as I can."
Why this is the answer
Holding urine allows bacteria to multiply. Regular voiding, good fluid intake, passing urine after intercourse and wiping front to back help reduce recurrence.
Answer
C · "I will hold my urine for as long as I can."
5.Med-surg: GI, perioperative & oncology
Answer: D · Tetanus immunisation status
Why this is the answer
Burns can be contaminated, so tetanus status is checked and a booster or immunoglobulin given if needed, according to guidelines.
Answer
D · Tetanus immunisation status
6.Med-surg: GI, perioperative & oncology
Answer: D · A non-smoking woman with motion sickness who will need opioids
Why this is the answer
Apfel risk factors are female sex, non-smoking status, a history of PONV or motion sickness, and postoperative opioids. Patients with more factors receive more preventive antiemetics.
Answer
D · A non-smoking woman with motion sickness who will need opioids
7.Clinical nursing
Answer: C · Unopened insulin is kept in the fridge and must not be frozen
Why this is the answer
Unopened insulin is refrigerated; in-use pens or vials are usually kept at room temperature for a limited time stated by the manufacturer. Frozen or overheated insulin must be discarded.
Answer
C · Unopened insulin is kept in the fridge and must not be frozen
8.Clinical nursing
Answer: C · Tumour lysis syndrome
Why this is the answer
Rapid tumour cell death releases potassium, phosphate and nucleic acids (forming uric acid), which can cause AKI and arrhythmias. Prevention includes IV hydration and drugs to lower uric acid.
Answer
C · Tumour lysis syndrome
9.Lab values & electrolytes
Answer: A · Potassium and creatinine
Why this is the answer
ACE inhibitors reduce aldosterone, so potassium can rise, and they lower the filtration pressure in the kidney, so creatinine can rise. Both are checked before and soon after starting or increasing the dose.Checked against:Hyperkalemia · StatPearls (NCBI Bookshelf) (2025)
Answer
A · Potassium and creatinine
10.Lab values & electrolytes
Answer: B · Past infection that has resolved, with immunity
Why this is the answer
The vaccine contains only surface antigen, so vaccination produces anti-HBs alone. A positive anti-HBc shows past or current infection; with HBsAg negative and anti-HBs positive, the infection has cleared and the person is immune.Checked against:Hepatitis Testing · MedlinePlus (NIH)
Answer
B · Past infection that has resolved, with immunity
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.43: within 7.35–7.45
PaCO₂ 22 mmHg: low (35–45)
HCO₃⁻ 14 mmol/L: low (22–26)
Compensation
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·18 + 8 = 35 → 33–37 mmHg
Compare
measured: 35 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: pause = 1.76 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
44 small boxes from R to R across the pause
Convert
pause = 44 × 0.04 s = 1.76 s
Compare with P–P
1.76 ÷ 0.76 ≈ 2.3 P–P cycles, not a whole number
Answer
pause = 1.76 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: dual-chamber (AV) paced rhythm
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: R–R = 21 small boxes, 1500 ÷ 21 ≈ 71 per minute.
2. Rhythm: regular, every R–R is 0.84 s.
3. P waves: each P wave follows its own pacing spike (atrial pacing).
4. AV interval: the second spike comes 0.16 s after the first one (the programmed AV delay).
5. QRS: 0.16 s, wide, right after the second spike (ventricular pacing).
Interpretation
dual-chamber (AV) paced rhythm
Answer
dual-chamber (AV) paced rhythm
The paced QRS is wide by nature; do not call it a bundle branch block or a ventricular rhythm.
15.Prioritization & delegation
Answer: C · Stop the transfusion and keep the IV open with normal saline via new tubing
Why this is the answer
For any suspected transfusion reaction, the nurse stops the transfusion at once, keeps the vein open with normal saline through new tubing and informs the provider and blood bank.
Answer
C · Stop the transfusion and keep the IV open with normal saline via new tubing
16.Prioritization & delegation
Answer: B · A surgical mask
Why this is the answer
A patient with an airborne infection wears a surgical mask outside the isolation room to contain respiratory particles. Staff caring for the patient wear fit-tested respirators, and the receiving department is told in advance.