Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with peripheral arterial disease has leg pain at night. Which position may ease it?
AHanging the legs down over the side of the bed
BApplying a hot water bottle directly to the feet
CWrapping the legs in compression bandages
DRaising the legs on pillows above heart level
2.Med-surg: cardiovascular & respiratoryHard
A patient with both COPD and heart disease is more breathless, with bilateral basal crackles, raised JVP, ankle swelling and a markedly raised NT-proBNP. Which problem is most likely driving this episode?
AAn asthma attack
BHyperventilation from anxiety
CDecompensated heart failure
DA primary spontaneous pneumothorax
3.Med-surg: neuro, endocrine & renalMedium
A stroke patient understands what is said but struggles to find words and speaks in short, effortful phrases. What type of aphasia is this?
AGlobal aphasia with no understanding
BDysarthria from weak facial muscles
CReceptive (Wernicke's) aphasia
DExpressive (Broca's) aphasia
4.Med-surg: neuro, endocrine & renalHard
A patient had rapid-acting insulin before lunch, then vomited the meal 15 minutes later. What should the nurse do?
AGive the evening long-acting insulin early to balance it
BIgnore it, because vomiting raises blood glucose
CMonitor glucose closely and tell the prescriber about the hypo risk
DGive another insulin dose because the meal was lost
5.Med-surg: GI, perioperative & oncologyMedium
Why is thiamine given to patients with alcohol dependence admitted to hospital?
ATo treat the cirrhosis directly
BTo prevent bleeding from varices
CTo reduce the craving for alcohol
DTo prevent Wernicke's encephalopathy
6.Med-surg: GI, perioperative & oncologyHard
Shortly after a spinal anaesthetic, a patient says their arms feel weak and it is hard to breathe, and the BP is falling. What is most likely?
AA post-dural puncture headache
BA high spinal block
CA normal spinal effect
DAn anxiety attack
7.Clinical nursingMedium
A patient is having a 12-lead ECG. Where are the chest electrodes placed?
AOn both shoulders and both hips only
BIn standard numbered positions across the front and left of the chest
CIn a straight line down the centre of the sternum from top to bottom
DAnywhere on the chest where the skin is clear
8.Clinical nursingHard
Which finding most strongly suggests a pulmonary embolism in a postoperative patient?
AWheeze that improves with salbutamol
BSlow heart rate with high blood pressure
CSudden breathlessness and pleuritic chest pain with tachycardia
DGradual onset of cough with yellow sputum and mild fever over a week
9.Lab values & electrolytesMedium
A patient on a heparin infusion has an aPTT of 110 seconds; the protocol target is 1.5–2.5 times the control of 30 seconds. What should the nurse do?
AGive vitamin K as prescribed and continue the infusion
BIncrease the infusion rate, because the result is above the target range
CFollow the heparin protocol, check for bleeding and inform the provider
DContinue unchanged and repeat the aPTT the next morning
10.Lab values & electrolytesHard
After a crush injury, a patient's urine dipstick is strongly positive for blood, but microscopy shows almost no red cells. CK is very high. What best explains this?
AA kidney stone is scraping the ureter lining
BThe sample was contaminated with menstrual blood
CMyoglobin from damaged muscle is in the urine
DBleeding is coming from the bladder lining
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.30, PaCO₂ 25 mmHg (3.3 kPa) and HCO₃⁻ 12 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.30PaCO₂ 25 mmHg (3.3 kPa)HCO₃⁻ 12 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.21, PaCO₂ 18 mmHg (2.4 kPa), HCO₃⁻ 7 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.21PaCO₂ 18 mmHg (2.4 kPa)HCO₃⁻ 7 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus tachycardia
2atrial flutter, 2:1 conduction
3ventricular tachycardia
4torsades de pointes
15.Prioritization & delegationMedium
Which patient should the nurse see first?
AA patient with chronic kidney disease due for dialysis tomorrow
BA patient with type 2 diabetes asking about the diet
CA patient with new slurred speech and a facial droop that started 30 minutes ago
DA patient with long-standing rheumatoid arthritis and the usual morning joint stiffness
16.Prioritization & delegationHard
Two hours after a femoral cardiac catheterization, the nurse sees blood spreading from the puncture site. What is the first action?
ARaise the head of the bed so the patient can sit up
BRemove the dressing and leave the site open to the air
CAsk the patient to bend the leg at the hip to stop the bleeding
DApply firm, direct pressure just above the puncture site
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Hanging the legs down over the side of the bed
Why this is the answer
Ischaemic rest pain is often relieved by lowering the legs, which improves arterial flow by gravity. Elevation worsens ischaemia. Compression is contraindicated in significant arterial disease, and direct heat can burn insensitive, ischaemic skin.
Answer
A · Hanging the legs down over the side of the bed
2.Med-surg: cardiovascular & respiratory
Answer: C · Decompensated heart failure
Why this is the answer
Basal crackles, raised JVP, oedema and a high natriuretic peptide point to heart failure rather than a COPD exacerbation alone. Distinguishing them matters, because treatment (diuretics and HF drugs versus bronchodilators and steroids) is different. Both may occur together.
Answer
C · Decompensated heart failure
3.Med-surg: neuro, endocrine & renal
Answer: D · Expressive (Broca's) aphasia
Why this is the answer
Expressive aphasia, from damage to Broca's area in the frontal lobe, causes non-fluent, effortful speech with relatively preserved understanding. Receptive aphasia causes fluent but meaningless speech and poor comprehension. Dysarthria is a motor speech problem with intact language.
Answer
D · Expressive (Broca's) aphasia
4.Med-surg: neuro, endocrine & renal
Answer: C · Monitor glucose closely and tell the prescriber about the hypo risk
Why this is the answer
The insulin will lower glucose without the carbohydrate it was meant to cover, so a hypo is likely. The nurse checks glucose often, offers carbohydrate the patient can keep down and escalates; IV glucose may be needed.
Answer
C · Monitor glucose closely and tell the prescriber about the hypo risk
5.Med-surg: GI, perioperative & oncology
Answer: D · To prevent Wernicke's encephalopathy
Why this is the answer
Thiamine deficiency is common in alcohol dependence and can cause Wernicke's encephalopathy (confusion, ataxia, eye signs). Thiamine is given early, ideally before or with glucose, as glucose can worsen deficiency.
Answer
D · To prevent Wernicke's encephalopathy
6.Med-surg: GI, perioperative & oncology
Answer: B · A high spinal block
Why this is the answer
If local anaesthetic spreads upwards, it can affect the arms, breathing muscles and cardiac nerves, causing hypotension and bradycardia. It is an emergency; help is called, and breathing and circulation are supported.
Answer
B · A high spinal block
7.Clinical nursing
Answer: B · In standard numbered positions across the front and left of the chest
Why this is the answer
The six chest leads (V1–V6) have standard anatomical positions, from the 4th intercostal space beside the sternum to the mid-axillary line. Wrong placement can change the ECG and lead to misinterpretation.
Answer
B · In standard numbered positions across the front and left of the chest
8.Clinical nursing
Answer: C · Sudden breathlessness and pleuritic chest pain with tachycardia
Why this is the answer
PE typically presents with sudden dyspnoea, chest pain on breathing, tachycardia, low oxygen saturation and sometimes haemoptysis or collapse.
Answer
C · Sudden breathlessness and pleuritic chest pain with tachycardia
9.Lab values & electrolytes
Answer: C · Follow the heparin protocol, check for bleeding and inform the provider
Why this is the answer
110 s is well above the target of about 45–75 s, so the bleeding risk is high. The nurse follows the heparin protocol, assesses for bleeding and informs the provider. Protamine is the reversal agent for heparin; vitamin K reverses warfarin.Checked against:Partial Thromboplastin Time (PTT) Test · MedlinePlus (NIH) (2026)
Answer
C · Follow the heparin protocol, check for bleeding and inform the provider
10.Lab values & electrolytes
Answer: C · Myoglobin from damaged muscle is in the urine
Why this is the answer
The dipstick blood test detects heme, which is present in both hemoglobin and myoglobin. Positive "blood" without red cells, together with a very high CK, indicates myoglobinuria from rhabdomyolysis, which can damage the kidneys. IV fluids and close monitoring of urine output and potassium are needed.Checked against:Myoglobin urine test · MedlinePlus (NIH) (2025); Rhabdomyolysis · MedlinePlus (NIH) (2025); Creatine Kinase · MedlinePlus (NIH) (2023)
Answer
C · Myoglobin from damaged muscle is in the urine
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.30: acidaemia (below 7.35)
PaCO₂ 25 mmHg: low (35–45)
HCO₃⁻ 12 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·7 + 8 = 18.5 → 16.5–20.5 mmHg
Compare
measured: 18 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: pause = 1.44 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
36 small boxes from R to R across the pause
Convert
pause = 36 × 0.04 s = 1.44 s
Compare with P–P
1.44 ÷ 0.88 ≈ 1.6 P–P cycles, not a whole number
Answer
pause = 1.44 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.14 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: C · A patient with new slurred speech and a facial droop that started 30 minutes ago
Why this is the answer
Sudden slurred speech and facial droop suggest a stroke, and treatment depends on time. The others have chronic, stable problems that can wait.
Answer
C · A patient with new slurred speech and a facial droop that started 30 minutes ago
16.Prioritization & delegation
Answer: D · Apply firm, direct pressure just above the puncture site
Why this is the answer
Direct manual pressure just above the puncture site compresses the femoral artery and stops bleeding. The patient keeps the leg straight, and the nurse checks vital signs and distal pulses and informs the provider.
Answer
D · Apply firm, direct pressure just above the puncture site