Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
After a prescribed IV fluid bolus for hypotension, what should the nurse do next?
AStop all monitoring if the patient says they feel better
BWait until the next routine observations in four hours
CStart a second fluid bolus straight away without checking anything
DReassess heart rate, blood pressure, urine output and lung sounds
2.Med-surg: cardiovascular & respiratoryHard
A patient is going home after a spontaneous pneumothorax treated with a chest drain. Which advice is correct?
AStop smoking and do not fly until a doctor confirms full resolution
BTake up scuba diving to strengthen the lungs
CExpect it never to happen again, so no follow-up is needed
DFly home as soon as possible so they can recover in comfort there
3.Med-surg: neuro, endocrine & renalMedium
After a thyroidectomy, why are suture or clip removers often kept at the bedside?
AThey are used to adjust the drain when it stops working
BThe sutures must be removed on the first evening after surgery
CThey are needed to take blood from the neck veins
DA neck haematoma can compress the airway and may need release
4.Med-surg: neuro, endocrine & renalHard
A 22-year-old with type 1 diabetes has glucose 28 mmol/L, ketones 5.2 mmol/L, pH 7.10 and potassium 5.9 mmol/L. Which statement about potassium is correct?
ATotal-body potassium is high, so a potassium binder is needed now
BTotal-body potassium is low, and the level will fall with treatment
CPotassium need not be rechecked once insulin has been started
DThe insulin should be withheld to keep the potassium level stable
5.Med-surg: GI, perioperative & oncologyMedium
Which liver function test pattern suggests bile duct obstruction?
AA low albumin with all other results normal
BHigh bilirubin with a markedly raised ALP and GGT
CNormal bilirubin with a low ALP and low GGT
DVery high ALT with a normal bilirubin only
6.Med-surg: GI, perioperative & oncologyHard
Which new prescription for a patient with cirrhosis should the nurse question?
ARegular ibuprofen for back pain
BThiamine supplements
CLactulose to keep the bowels open
DSpironolactone for ascites
7.Clinical nursingMedium
A patient taking digoxin has nausea, a pulse of 48/min and complains that everything looks yellow. What should you suspect?
ADigoxin toxicity
BHypoglycaemia
CHyperthyroidism
DA normal side effect needing no action
8.Clinical nursingHard
Soon after starting chemotherapy for a high-grade lymphoma, a patient has rising potassium, phosphate and uric acid with falling urine output. What is the most likely cause?
AAdrenal insufficiency
BSyndrome of inappropriate ADH secretion
CTumour lysis syndrome
DRefeeding syndrome
9.Lab values & electrolytesMedium
A patient takes high-dose biotin supplements for hair and nails. Why should the nurse report this before blood tests?
ABiotin can distort some immunoassays, such as troponin or TSH
BBiotin lowers the hemoglobin by destroying the red cells
CBiotin causes a true rise in blood glucose in all patients
DBiotin makes the blood clot in the tube before testing
10.Lab values & electrolytesHard
A patient has fever, chills, flank pain and costovertebral angle tenderness. Urinalysis shows many white cells and white cell casts. Which condition is most likely?
ASimple cystitis
BNephrotic syndrome
CAcute pyelonephritis
DGlomerulonephritis
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.44, PaCO₂ 59 mmHg (7.9 kPa) and HCO₃⁻ 39 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.44PaCO₂ 59 mmHg (7.9 kPa)HCO₃⁻ 39 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.11, PaCO₂ 36 mmHg (4.8 kPa), HCO₃⁻ 11 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.11PaCO₂ 36 mmHg (4.8 kPa)HCO₃⁻ 11 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2sinus bradycardia
3normal sinus rhythm
4sinus tachycardia
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1supraventricular tachycardia (SVT)
2torsades de pointes
3idioventricular rhythm
4atrial flutter, 2:1 conduction
15.Prioritization & delegationMedium
A nurse takes a telephone order from a provider. What must the nurse do?
ARemember the order and write it in the chart at the end of the shift
BAsk the ward clerk to take the order on the nurse’s behalf instead
CWrite the order down and read it back to the provider to confirm it
DCarry out the order first and ask the provider to confirm it later
16.Prioritization & delegationHard
A child who had a tonsillectomy this morning is swallowing again and again while asleep. What should the nurse suspect?
AHunger after fasting for surgery
BBleeding from the operation site
CNormal swallowing during sleep
DA sore throat from the breathing tube
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Reassess heart rate, blood pressure, urine output and lung sounds
Why this is the answer
A fluid challenge is followed by reassessment of perfusion (heart rate, BP, capillary refill, mental state, urine output) and signs of overload such as crackles, raised JVP or worsening breathlessness. The findings are reported to decide on further fluid, vasopressors or escalation.
Answer
D · Reassess heart rate, blood pressure, urine output and lung sounds
2.Med-surg: cardiovascular & respiratory
Answer: A · Stop smoking and do not fly until a doctor confirms full resolution
Why this is the answer
Patients should not fly until the pneumothorax has resolved on X-ray, often with an extra waiting period. Diving is usually avoided permanently unless definitive surgery has been done. Smoking increases recurrence, which is common, so patients learn to seek help for new breathlessness or chest pain.
Answer
A · Stop smoking and do not fly until a doctor confirms full resolution
3.Med-surg: neuro, endocrine & renal
Answer: D · A neck haematoma can compress the airway and may need release
Why this is the answer
A neck haematoma after thyroid surgery can quickly compress the airway. Many units keep clip or suture removers and airway equipment at the bedside so the wound can be opened in an emergency. The nurse watches for swelling, stridor and difficulty breathing.
Answer
D · A neck haematoma can compress the airway and may need release
4.Med-surg: neuro, endocrine & renal
Answer: B · Total-body potassium is low, and the level will fall with treatment
Why this is the answer
In DKA, potassium moves out of cells while the kidneys lose it in the urine, so serum potassium can be normal or high despite a large total deficit. Fluids and insulin lower it quickly. Potassium is monitored closely and replaced once it falls into the normal range, as per protocol.
Answer
B · Total-body potassium is low, and the level will fall with treatment
5.Med-surg: GI, perioperative & oncology
Answer: B · High bilirubin with a markedly raised ALP and GGT
Why this is the answer
Cholestasis raises alkaline phosphatase and gamma-GT, with conjugated bilirubin. Hepatocellular injury, such as hepatitis, mainly raises ALT and AST.
Answer
B · High bilirubin with a markedly raised ALP and GGT
6.Med-surg: GI, perioperative & oncology
Answer: A · Regular ibuprofen for back pain
Why this is the answer
NSAIDs can cause kidney injury, fluid retention and GI bleeding in cirrhosis and should be avoided. Paracetamol at a reduced, carefully reviewed dose is usually preferred for pain.
Answer
A · Regular ibuprofen for back pain
7.Clinical nursing
Answer: A · Digoxin toxicity
Why this is the answer
Digoxin toxicity causes nausea, vomiting, bradycardia, arrhythmias and visual disturbances. Low potassium increases the risk. Withhold the dose and report.
Answer
A · Digoxin toxicity
8.Clinical nursing
Answer: C · Tumour lysis syndrome
Why this is the answer
Rapid tumour cell death releases potassium, phosphate and nucleic acids (forming uric acid), which can cause AKI and arrhythmias. Prevention includes IV hydration and drugs to lower uric acid.
Answer
C · Tumour lysis syndrome
9.Lab values & electrolytes
Answer: A · Biotin can distort some immunoassays, such as troponin or TSH
Why this is the answer
Many immunoassays use biotin-streptavidin binding, and high blood biotin levels can give falsely high or low results, for example a falsely low troponin or abnormal thyroid tests. The laboratory and prescriber should know about biotin use.Checked against:Troponin Test · MedlinePlus (NIH) (2023); Biotin Interference with Troponin Lab Tests - Assays Subject to Biotin Interference · U.S. FDA (2022)
Answer
A · Biotin can distort some immunoassays, such as troponin or TSH
10.Lab values & electrolytes
Answer: C · Acute pyelonephritis
Why this is the answer
White cell casts show that the inflammation is in the kidney itself, not just the bladder. With fever and flank pain this indicates pyelonephritis. Glomerulonephritis typically causes red cell casts, and nephrotic syndrome causes heavy protein loss.Checked against:Urinary casts · MedlinePlus (NIH) (2025); Glomerulonephritis · MedlinePlus (NIH) (2025)
Answer
C · Acute pyelonephritis
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.44: within 7.35–7.45
PaCO₂ 59 mmHg: high (35–45)
HCO₃⁻ 39 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 46.3–50.3 mmHg, so the measured 59 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·11 + 8 = 24.5 → 22.5–26.5 mmHg
Compare
measured: 36 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: first-degree AV block
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 24 small boxes, 1500 ÷ 24 ≈ 63 per minute.
2. Rhythm: regular, every R–R is 0.96 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.32 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
first-degree AV block
Answer
first-degree AV block
14.ECG rhythm strip interpretation
Answer: torsades de pointes
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: very fast, the complexes are about 6 small boxes apart (about 250 per minute).
2. Rhythm: fast and roughly regular, but the height and direction of the complexes change in a repeating spindle pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: wide and polymorphic; the complexes twist around the baseline, pointing up for a few beats and then down.
Interpretation
torsades de pointes
Answer
torsades de pointes
Torsades de pointes is a polymorphic VT linked to a prolonged QT interval. This is identification practice only.
15.Prioritization & delegation
Answer: C · Write the order down and read it back to the provider to confirm it
Why this is the answer
For telephone and verbal orders, the nurse writes down the full order and reads it back so the provider can confirm it. This “read-back” prevents errors from mishearing.
Answer
C · Write the order down and read it back to the provider to confirm it
16.Prioritization & delegation
Answer: B · Bleeding from the operation site
Why this is the answer
Frequent swallowing after tonsillectomy is a classic sign of bleeding. The nurse checks the throat with a light, looks at vital signs and reports at once.