Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why must inspired air be humidified for a patient with a tracheostomy?
AHumidified air contains more oxygen than dry air at the same flow
BDry air is needed to stop secretions forming in the trachea
CHumidification prevents the cuff from deflating
DThe nose and upper airway, which warm and moisten air, are bypassed
2.Med-surg: cardiovascular & respiratoryHard
A patient with heart failure is breathless at rest, with cool peripheries, a systolic BP of 80 mmHg and falling urine output. What does this suggest?
AAnxiety causing a vasovagal response
BCardiogenic shock with poor tissue perfusion
CMild dehydration that oral fluids will correct
DStable, well-compensated chronic heart failure
3.Med-surg: neuro, endocrine & renalMedium
An 82-year-old taking apixaban fell three weeks ago. Since then their family has noticed increasing confusion and headaches. Which condition is most likely?
ANormal ageing with mild memory loss
BChronic subdural haematoma
CAcute extradural haematoma
DSubarachnoid haemorrhage from an aneurysm
4.Med-surg: neuro, endocrine & renalHard
On the first day after a kidney transplant, urine output suddenly falls from 200 mL/h to 10 mL/h. What should the nurse check first?
AThe patient's blood glucose level
BWhether the patient has eaten
CThe patient's temperature and pulse
DThat the catheter is not blocked or kinked
5.Med-surg: GI, perioperative & oncologyMedium
Which change suggests that a burn wound is becoming infected?
AThe wound becoming pink and a little smaller at each dressing change
BDry, healing skin with mild itching
CA partial-thickness burn becoming deeper, with new discolouration
DLess exudate on each dressing change
6.Med-surg: GI, perioperative & oncologyHard
A patient with a toe ulcer says the leg pain is worse at night and eases when they hang the leg over the side of the bed. What does this suggest?
AVenous insufficiency
BLymphoedema
CArterial insufficiency
DNeuropathic itching
7.Clinical nursingMedium
Which is a first-line nursing measure to help prevent constipation in hospital?
AKeeping the patient in bed
BRestricting fluids to reduce urine output
CEncouraging fluids, fibre and mobility
DGiving an enema to every patient on admission
8.Clinical nursingHard
Which finding suggests hypocalcaemia?
ASpasm of the hand when a blood pressure cuff is inflated on the arm
BA flapping tremor of the outstretched hands
CA slow, irregular pulse with nausea and yellow-tinged vision
DSevere thirst with a large urine output and constipation
9.Lab values & electrolytesMedium
A patient had a total thyroidectomy yesterday. Which laboratory value is most important to monitor in the first days after surgery?
ASerum potassium
BSerum glucose
CSerum sodium
DSerum calcium
10.Lab values & electrolytesHard
An RN cares for a patient on a 24-hour urine collection. Which task can be delegated to unlicensed assistive personnel (UAP), such as a nursing or healthcare assistant?
ADeciding whether to restart the collection after a missed sample
BTeaching the patient why the 24-hour collection is needed
CInterpreting the creatinine clearance result when it comes back
DSaving all urine in the collection container as instructed
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 18 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 18 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.33, PaCO₂ 35 mmHg (4.7 kPa), HCO₃⁻ 18 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.33PaCO₂ 35 mmHg (4.7 kPa)HCO₃⁻ 18 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval on this lead II strip, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QT = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type I (Wenckebach)
2atrial fibrillation
3first-degree AV block
4second-degree AV block type II
15.Prioritization & delegationMedium
A patient receiving an aminoglycoside antibiotic, such as gentamicin, reports ringing in the ears. What should the nurse do?
AGive the next dose early to finish the course
BAdvise the patient to use ear drops
CReassure the patient that it is a normal effect
DHold the next dose and report it promptly
16.Prioritization & delegationHard
A patient is bleeding internally after a fall. Which finding is usually an early sign of hypovolemic shock?
ARestlessness and a rising heart rate while the blood pressure is still normal
BLoss of consciousness with gasping breaths
CA very low blood pressure with fixed, dilated pupils
DA slow heart rate with warm, dry, flushed skin and a normal blood pressure throughout
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · The nose and upper airway, which warm and moisten air, are bypassed
Why this is the answer
The tracheostomy bypasses the nose, mouth and pharynx, which warm, filter and humidify air. Without humidification, secretions become thick and can block the tube. Heat and moisture exchangers, humidified oxygen and nebulised saline are used.
Answer
D · The nose and upper airway, which warm and moisten air, are bypassed
2.Med-surg: cardiovascular & respiratory
Answer: B · Cardiogenic shock with poor tissue perfusion
Why this is the answer
Cardiogenic shock is pump failure with hypotension and hypoperfusion (cool skin, oliguria, confusion, raised lactate), often with pulmonary congestion. It needs urgent critical care review. Large fluid boluses can worsen congestion unless guided by careful assessment.
Answer
B · Cardiogenic shock with poor tissue perfusion
3.Med-surg: neuro, endocrine & renal
Answer: B · Chronic subdural haematoma
Why this is the answer
Older people have brain atrophy that stretches the bridging veins, and anticoagulants increase bleeding. A slow venous bleed can cause gradual confusion, headache or weakness over weeks. A CT scan is needed.
Answer
B · Chronic subdural haematoma
4.Med-surg: neuro, endocrine & renal
Answer: D · That the catheter is not blocked or kinked
Why this is the answer
A sudden drop in output after transplant may be caused by a blocked catheter, often from clots. The nurse checks the tubing and may flush the catheter per protocol, and then escalates urgently, because vascular thrombosis or rejection are also possible.
Answer
D · That the catheter is not blocked or kinked
5.Med-surg: GI, perioperative & oncology
Answer: C · A partial-thickness burn becoming deeper, with new discolouration
Why this is the answer
Signs of burn wound infection include conversion to a deeper burn, new dark or green discolouration, increasing pain, offensive exudate, spreading redness and systemic signs such as fever or tachycardia.
Answer
C · A partial-thickness burn becoming deeper, with new discolouration
6.Med-surg: GI, perioperative & oncology
Answer: C · Arterial insufficiency
Why this is the answer
Rest pain eased by dependency is typical of severe peripheral arterial disease. Elevating the leg worsens pain, and compression is avoided. Vascular assessment is needed.
Answer
C · Arterial insufficiency
7.Clinical nursing
Answer: C · Encouraging fluids, fibre and mobility
Why this is the answer
Adequate fluids, a fibre-rich diet, mobility and privacy for toileting help prevent constipation. Laxatives are added if needed, especially with opioids.
Answer
C · Encouraging fluids, fibre and mobility
8.Clinical nursing
Answer: A · Spasm of the hand when a blood pressure cuff is inflated on the arm
Why this is the answer
Trousseau's sign, carpal spasm during cuff inflation, and Chvostek's sign, facial twitching on tapping the facial nerve, indicate neuromuscular irritability from low calcium.
Answer
A · Spasm of the hand when a blood pressure cuff is inflated on the arm
9.Lab values & electrolytes
Answer: D · Serum calcium
Why this is the answer
The parathyroid glands can be injured or removed during thyroidectomy, so parathyroid hormone falls and hypocalcemia can follow. The nurse monitors calcium and checks for tingling around the mouth, muscle cramps and Chvostek or Trousseau signs.Checked against:Hypoparathyroidism · MedlinePlus (NIH) (2026)
Answer
D · Serum calcium
10.Lab values & electrolytes
Answer: D · Saving all urine in the collection container as instructed
Why this is the answer
UAP can help with routine, standard tasks such as saving urine and keeping the container cool as instructed. Teaching, clinical decisions and interpreting results require nursing judgment and stay with the RN.Checked against:24-Hour Urine Collection and Analysis · StatPearls (NCBI Bookshelf) (2024)
Answer
D · Saving all urine in the collection container as instructed
11.Arterial blood gas interpretation
Answer: PaCO₂ = 35 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·18 + 8 = 35 mmHg
range: 33–37 mmHg
Answer
PaCO₂ = 35 mmHg
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·18 + 8 = 35 → 33–37 mmHg
Compare
measured: 35 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: QT = 0.5 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
12.5 small boxes from the start of the QRS to the end of the T wave
Convert
QT = 12.5 × 0.04 s = 0.5 s
Answer
QT = 0.5 s
A rough rule: at normal rates the QT should be less than half the R–R interval (here R–R = 1.00 s).
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 1.00 s, 60 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: lengthens 0.16 → 0.28 s, then a P wave is not conducted.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: D · Hold the next dose and report it promptly
Why this is the answer
Aminoglycosides can cause ototoxicity, which may be permanent. Tinnitus or hearing loss is reported promptly, and drug levels and kidney function are checked.
Answer
D · Hold the next dose and report it promptly
16.Prioritization & delegation
Answer: A · Restlessness and a rising heart rate while the blood pressure is still normal
Why this is the answer
In early shock, the body keeps the blood pressure up by raising the heart rate and narrowing vessels, so restlessness and tachycardia appear first. A falling blood pressure is a later sign.
Answer
A · Restlessness and a rising heart rate while the blood pressure is still normal