NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 24 kg is prescribed 7.5 mg/kg of a drug. The stock solution contains 20 mg/mL. Draw up the dose: what volume V do you give?

24 kg7.5 mg/kg20 mg/mL
V = mL
2.Dosage calculationsHard
40 mg/1 mLV = ? mL

A child weighing 18 kg is prescribed 10 mg/kg per dose of an oral suspension that contains 40 mg in 1 mL. What volume V do you give?

18 kg10 mg/kg40 mg/1 mL
V = mL
3.IV infusion ratesMedium
250 mL15 gtt/mL2 h? gtt/min

Infuse 250 mL over 2 hours with a giving set of 15 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

250 mL2 h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
450 mL15 gtt/mL20 gtt/mint = ? h

A drip runs at 20 gtt/min through a set of 15 gtt/mL. There are 450 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

20 gtt/min15 gtt/mL450 mL
t = h
5.Pediatric & critical-care dosingMedium
100 units50 mLregular insulin? mL/h79 kg0.1 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 50 mL. The order is 0.1 units/kg/h for a patient who weighs 79 kg. Find the pump rate R in mL/h. Round to one decimal place.

100 units/50 mL0.1 units/kg/h79 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine? mL/h108 kg12.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 500 mg in 250 mL. The order is 12.5 mcg/kg/min for a patient who weighs 108 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

500 mg/250 mL12.5 mcg/kg/min108 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftwater200 mLsoup180 mLmilk240 mLIV infusion75 mL/h × 12 hIV antibiotic1 × 100 mLurine300 mLurine475 mLurine400 mLurine300 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 57 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

57 kg12 hurine: 300 mLurine: 475 mLurine: 400 mLurine: 300 mLvomit: 100 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
500 mL60 mL/hstart 13:1517:45: ? mL

Practice exercise (made-up values, not clinical guidance). A 500 mL bag was started at 13:15 and runs by pump at 60 mL/h. How many mL V are left in the bag at 17:45?

500 mL60 mL/h13:15 → 17:45
V = mL
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C101.5 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 101.5 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

101.5 °F
T = °C
10.Nursing math & unit conversionsHard
1½ tsp? mL3 fl oz? mL2 tbsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 1½ tsp of cough syrup, 3 fl oz of juice, 2 tbsp of liquid supplement. Using the equivalents given, find the total oral intake V in mL.

1 tsp = 5 mL1 fl oz = 30 mL1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 9 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 7.5·24 = 180 mg

Volume

V = 180/20 = 9 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 9 mL
2.Dosage calculations

Answer: V = 4.5 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

10·18 = 180 mg

Volume

V = (180/40)·1 = 4.5 mL

Answer

V = 4.5 mL
3.IV infusion rates

Answer: R = 31 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

2·60 = 120 min

Drip rate

R = 250·15/120 = 31.25 ≈ 31 gtt/min

Answer

R = 31 gtt/min

At the bedside you round to the nearest whole drop: 31 gtt/min.

4.IV infusion rates

Answer: t = 5.6 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

20·60/15 = 80 mL/h

Time left

t = 450/80 = 5.625 ≈ 5.6 h

Answer

t = 5.6 h
5.Pediatric & critical-care dosing

Answer: R = 4 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.1·79 = 7.9 units/h

Concentration

100/50 = 2 units/mL

Pump rate

R = 7.9/2 = 3.95 ≈ 4 mL/h

Answer

R = 4 mL/h
6.Pediatric & critical-care dosing

Answer: R = 40.5 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 mg = 500 000 mcg
500 000/250 = 2000 mcg/mL

Dose per minute and per hour

12.5·108 = 1350 mcg/min
1350·60 = 81000 mcg/h

Pump rate

R = 81000/2000 = 40.5 mL/h

Answer

R = 40.5 mL/h
7.IV fluids & fluid balance

Answer: U = 2.16 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

300 + 475 + 400 + 300 = 1475 mL

Per kilogram per hour

U = 1475/(57·12) = 2.156 ≈ 2.16 mL/kg/h

Answer

U = 2.16 mL/kg/h
8.IV fluids & fluid balance

Answer: V = 230 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

13:15 → 17:45 = 4.5 h

Volume infused

60·4.5 = 270 mL

Volume left

V = 500 − 270 = 230 mL

Answer

V = 230 mL
9.Nursing math & unit conversions

Answer: T = 38.6 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

101.5 − 32 = 69.5

Multiply by 5/9

T = 69.5·5/9 = 38.61 ≈ 38.6 °C

Answer

T = 38.6 °C
10.Nursing math & unit conversions

Answer: V = 127.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

1½ tsp = 1.5·5 = 7.5 mL
3 fl oz = 3·30 = 90 mL
2 tbsp = 2·15 = 30 mL

Add

V = 7.5 + 90 + 30 = 127.5 mL

Answer

V = 127.5 mL

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