NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 18 kg is prescribed 5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

18 kg5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
50k units250 mL? mL/h1500 units/h

An infusion contains 50000 units of a drug in 250 mL. The prescription is 1500 units per hour. At what rate R do you set the pump, in mL/h?

50000 units/250 mL1500 units/h
R = mL/h
3.IV infusion ratesMedium
500 mL15 gtt/mL5 h? gtt/min

Infuse 500 mL over 5 hours with a giving set of 15 gtt/mL. Find the drip rate R in drops per minute.

500 mL5 h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
450 mLleft? mL/h6 h left

500 mL was ordered over 8 hours. After 2 hours you find that 450 mL is still in the bag, and the order must still finish on time. By what percentage Δ must the original pump rate be increased?

500 mL / 8 hafter 2 h: 450 mL
Δ = %
5.Pediatric & critical-care dosingMedium
100 units250 mLregular insulin? mL/h4 units/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 250 mL. The order is 4 units/h. Find the pump rate R in mL/h. Round to one decimal place.

100 units/250 mL4 units/h
R = mL/h
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine24 mL/h77 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 24 mL/h. The patient weighs 77 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL24 mL/h77 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice150 mLsoup200 mLice chips240 mLIV infusion75 mL/h × 8 hIV antibiotic2 × 50 mLurine250 mLurine500 mLurine200 mLurine300 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL. Count ice chips as half their volume.

juice: 150 mLsoup: 200 mLice chips: 240 mLIV infusion: 75 mL/h × 8 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
500 mL→ 200 mL/hstart 07:30ttotal​ = ? h75 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 07:30 at 75 mL/h. After 4 hours the rate is changed to 200 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL75 mL/h · 4 h200 mL/h
t = h
9.Nursing math & unit conversionsMedium
6 ft 10 in1 ft = 12 in1 in = 2.54 cmh = ? cm

Practice exercise (made-up values, not clinical guidance). A patient is 6 ft 10 in tall. Using 1 ft = 12 in and 1 in = 2.54 cm, find the height h in centimetres, to the nearest whole centimetre.

6 ft 10 in1 ft = 12 in1 in = 2.54 cm
h = cm
10.Nursing math & unit conversionsHard
½ cup? mL1 fl oz? mL1 tbsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes ½ cup of tea, 1 fl oz of juice, 1 tbsp of liquid supplement. Using the equivalents given, find the total oral intake V in mL.

1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 3.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·18 = 90 mg

Volume

V = 90/25 = 3.6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 3.6 mL
2.Dosage calculations

Answer: R = 7.5 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

50000/250 = 200 units/mL

Pump rate

R = 1500/200 = 7.5 mL/h

Answer

R = 7.5 mL/h
3.IV infusion rates

Answer: R = 25 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

5·60 = 300 min

Drip rate

R = 500·15/300 = 25 gtt/min

Answer

R = 25 gtt/min
4.IV infusion rates

Answer: Δ = 20 %

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

500/8 = 62.5 mL/h

New rate

R = 450/6 = 75 mL/h

Percentage change

Δ = (75 − 62.5)/62.5·100% = 20%

Answer

Δ = 20%

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

5.Pediatric & critical-care dosing

Answer: R = 10 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

100/250 = 0.4 units/mL

Pump rate

R = 4/0.4 = 10 mL/h

Answer

R = 10 mL/h
6.Pediatric & critical-care dosing

Answer: D = 8.3 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

24·1600 = 38400 mcg/h
38400/60 = 640 mcg/min

Per kilogram

D = 640/77 = 8.312 ≈ 8.3 mcg/kg/min

Answer

D = 8.3 mcg/kg/min
7.IV fluids & fluid balance

Answer: I = 1170 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 150 + 200 = 350 mL
ice chips: 240/2 = 120 mL
IV infusion: 75·8 = 600 mL
IV antibiotic: 2·50 = 100 mL
I = 1170 mL

Answer

I = 1170 mL
8.IV fluids & fluid balance

Answer: t = 5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·4 = 300 mL
500 − 300 = 200 mL left

Second part

200/200 = 1 h

Total time

t = 4 + 1 = 5 h

Answer

t = 5 h

That is about 5 h 00 min, so the bag runs out at about 12:30.

9.Nursing math & unit conversions

Answer: h = 208 cm

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Height in inches

6·12 + 10 = 82 in

Inches to centimetres

h = 82·2.54 = 208.3 ≈ 208 cm

Answer

h = 208 cm
10.Nursing math & unit conversions

Answer: V = 165 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

½ cup = 0.5·240 = 120 mL
1 fl oz = 1·30 = 30 mL
1 tbsp = 1·15 = 15 mL

Add

V = 120 + 30 + 15 = 165 mL

Answer

V = 165 mL

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