NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
88 kgBSA = 1.78 m²135 mg/m²D = ? mg

A patient weighing 88 kg has a body surface area of 1.78 m². The prescription is 135 mg/m². Find the dose D in mg.

88 kgBSA = 1.78 m²135 mg/m²
D = mg
2.Dosage calculationsHard
40 mg/1 mLV = ? mL

A child weighing 24 kg is prescribed 20 mg/kg per dose of an oral suspension that contains 40 mg in 1 mL. What volume V do you give?

24 kg20 mg/kg40 mg/1 mL
V = mL
3.IV infusion ratesMedium
420 mLleft? mL/h6 h left

500 mL was ordered over 8 hours. After 2 hours you find that 420 mL is still in the bag, and the order must still finish on time. To what rate R in mL/h must the pump be reset?

500 mL / 8 hafter 2 h: 420 mL
R = mL/h
4.IV infusion ratesHard
200 mL60 gtt/mL42 gtt/mint = ? h

A drip runs at 42 gtt/min through a set of 60 gtt/mL. There are 200 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

42 gtt/min60 gtt/mL200 mL
t = h
5.Pediatric & critical-care dosingMedium
25 000 units500 mLheparin? mL/h68 kg16 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 500 mL. The order is 16 units/kg/h for a patient who weighs 68 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/500 mL16 units/kg/h68 kg
R = mL/h
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine36 mL/h98 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 36 mL/h. The patient weighs 98 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL36 mL/h98 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater250 mLsoup250 mLjuice150 mLIV infusion80 mL/h × 8 hIV antibiotic2 × 100 mLurine325 mLurine200 mLurine325 mLurine150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

water: 250 mLsoup: 250 mLjuice: 150 mLIV infusion: 80 mL/h × 8 hIV antibiotic: 2 × 100 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL→ 50 mL/hstart 09:00ttotal​ = ? h75 mL/h × 2 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 09:00 at 75 mL/h. After 2 hours the rate is changed to 50 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL75 mL/h · 2 h50 mL/h
t = h
9.Nursing math & unit conversionsMedium
12345678910111203:20?3:20 PM2:20 AM3:20 AM5:20 AM

Practice exercise (made-up values, not clinical guidance). A dose is charted at 03:20 (24-hour clock). Which entry is the same time on the 12-hour clock? Click it.

03:20
  1. 13:20 PM
  2. 22:20 AM
  3. 33:20 AM
  4. 45:20 AM
10.Nursing math & unit conversionsHard
1 tsp · 4/day · 7 d? mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 1 tsp of an oral suspension every 6 hours for 7 days. Using 1 tsp = 5 mL, how many mL V are needed for the whole course?

1 tspevery 6 hours7 days1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 240.3 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Dose

D = 135·1.78 = 240.3 mg

Answer

D = 240.3 mg
2.Dosage calculations

Answer: V = 12 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

20·24 = 480 mg

Volume

V = (480/40)·1 = 12 mL

Answer

V = 12 mL
3.IV infusion rates

Answer: R = 70 mL/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

500/8 = 62.5 mL/h

New rate

R = 420/6 = 70 mL/h

Answer

R = 70 mL/h

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

4.IV infusion rates

Answer: t = 4.8 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

42·60/60 = 42 mL/h

Time left

t = 200/42 = 4.762 ≈ 4.8 h

Answer

t = 4.8 h
5.Pediatric & critical-care dosing

Answer: R = 21.8 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

16·68 = 1 088 units/h

Concentration

25 000/500 = 50 units/mL

Pump rate

R = 1088/50 = 21.76 ≈ 21.8 mL/h

Answer

R = 21.8 mL/h
6.Pediatric & critical-care dosing

Answer: D = 9.8 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

36·1600 = 57600 mcg/h
57600/60 = 960 mcg/min

Per kilogram

D = 960/98 = 9.796 ≈ 9.8 mcg/kg/min

Answer

D = 9.8 mcg/kg/min
7.IV fluids & fluid balance

Answer: I = 1490 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 250 + 250 + 150 = 650 mL
IV infusion: 80·8 = 640 mL
IV antibiotic: 2·100 = 200 mL
I = 1490 mL

Answer

I = 1490 mL
8.IV fluids & fluid balance

Answer: t = 19 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·2 = 150 mL
1000 − 150 = 850 mL left

Second part

850/50 = 17 h

Total time

t = 2 + 17 = 19 h

Answer

t = 19 h

That is about 19 h 00 min, so the bag runs out at about 04:00.

9.Nursing math & unit conversions

Answer: 3:20 AM

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

03 → 3 AM

Answer

3:20 AM

Answer

3:20 AM
10.Nursing math & unit conversions

Answer: V = 140 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

1 tsp = 1·5 = 5 mL

Whole course

V = 5 mL × 4/day × 7 = 140 mL

Answer

V = 140 mL

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