NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
80 kg25 mg/kg/day4× per dayD = ? mg

A patient weighs 80 kg. The prescribed dose is 25 mg/kg per day, given in 4 equal doses. How many milligrams D are given per dose?

80 kg25 mg/kg/day4× per day
D = mg
2.Dosage calculationsHard
125 mg/5 mLV = ? mL

A child weighing 24 kg is prescribed 10 mg/kg per dose of an oral suspension that contains 125 mg in 5 mL. What volume V do you give?

24 kg10 mg/kg125 mg/5 mL
V = mL
3.IV infusion ratesMedium
15 gtt/mL100 mL/h? gtt/min

An infusion is ordered at 100 mL/h, but no pump is available. It runs by gravity through a giving set of 15 gtt/mL. Find the drip rate R in drops per minute.

100 mL/h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
750 mL20 gtt/mL50 gtt/mint = ? h

A drip runs at 50 gtt/min through a set of 20 gtt/mL. There are 750 mL left in the bag. How many hours t until it is empty?

50 gtt/min20 gtt/mL750 mL
t = h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL80 units/kg · 54 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 80 units/kg for a patient who weighs 54 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

80 units/kg54 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine? mL/h102 kg10 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 800 mg in 500 mL. The order is 10 mcg/kg/min for a patient who weighs 102 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

800 mg/500 mL10 mcg/kg/min102 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftmilk240 mLtea150 mLjelly120 mLIV infusion125 mL/h × 12 hIV antibiotic1 × 100 mLurine200 mLurine400 mLvomit150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 96 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

96 kg12 hurine: 200 mLurine: 400 mLvomit: 150 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
500 mL100 mL infused120 mL/h10:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 120 mL/h. At 10:00, 100 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL100 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
9.1386 mL? mLround to 0.1 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for an injection gives 9.1386 mL. The rule in this exercise is that volumes of 1 mL or more are rounded to the nearest tenth of a mL. What value x do you record?

9.1386 mL
x = mL
10.Nursing math & unit conversionsHard
2 cups? mL6 fl oz? mL3 tsp? mL3 tbsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 2 cups of tea, 6 fl oz of juice, 3 tsp of cough syrup, 3 tbsp of liquid supplement. Using the equivalents given, find the total oral intake V in mL.

1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL1 tsp = 5 mL1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 500 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

25·80 = 2000 mg

Per dose

D = 2000/4 = 500 mg

Answer

D = 500 mg
2.Dosage calculations

Answer: V = 9.6 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

10·24 = 240 mg

Volume

V = (240/125)·5 = 9.6 mL

Answer

V = 9.6 mL
3.IV infusion rates

Answer: R = 25 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Millilitres per minute

100/60 = 1.667 mL/min

Drip rate

R = 1.667·15 = 25 gtt/min

Answer

R = 25 gtt/min
4.IV infusion rates

Answer: t = 5 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

50·60/20 = 150 mL/h

Time left

t = 750/150 = 5 h

Answer

t = 5 h
5.Pediatric & critical-care dosing

Answer: V = 4.3 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

80·54 = 4 320 units

Volume

V = 4320/1000 = 4.32 ≈ 4.3 mL

Answer

V = 4.3 mL
6.Pediatric & critical-care dosing

Answer: R = 38.3 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 mg = 800 000 mcg
800 000/500 = 1600 mcg/mL

Dose per minute and per hour

10·102 = 1020 mcg/min
1020·60 = 61200 mcg/h

Pump rate

R = 61200/1600 = 38.25 ≈ 38.3 mL/h

Answer

R = 38.3 mL/h
7.IV fluids & fluid balance

Answer: U = 0.52 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

200 + 400 = 600 mL

Per kilogram per hour

U = 600/(96·12) = 0.5208 ≈ 0.52 mL/kg/h

Answer

U = 0.52 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 3.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 100 = 400 mL

Time

t = 400/120 = 3.333 ≈ 3.3 h

Answer

t = 3.3 h

That is about 3 h 20 min, so the bag runs out at about 13:20.

9.Nursing math & unit conversions

Answer: x = 9.1 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

9.1386 → 1

Only the next digit decides

9.1386 → 3
3 is 4 or less, so 1 stays.
The digits after it (86) are ignored: round once, never step by step.

Round

x = 9.1 mL

Answer

x = 9.1 mL
10.Nursing math & unit conversions

Answer: V = 720 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

2 cups = 2·240 = 480 mL
6 fl oz = 6·30 = 180 mL
3 tsp = 3·5 = 15 mL
3 tbsp = 3·15 = 45 mL

Add

V = 480 + 180 + 15 + 45 = 720 mL

Answer

V = 720 mL

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