NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 23 kg is prescribed 10 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

23 kg10 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 2000 micrograms. The ampoule contains 4 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

2000 mcg4 mg/mL
V = mL
3.IV infusion ratesMedium
60 gtt/mL60 mL/h? gtt/min

An infusion is ordered at 60 mL/h, but no pump is available. It runs by gravity through a giving set of 60 gtt/mL. Find the drip rate R in drops per minute.

60 mL/h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
600 mL20 gtt/mL40 gtt/mint = ? h

A drip runs at 40 gtt/min through a set of 20 gtt/mL. There are 600 mL left in the bag. How many hours t until it is empty?

40 gtt/min20 gtt/mL600 mL
t = h
5.Pediatric & critical-care dosingMedium
25 000 units250 mLheparin? mL/h72 kg12 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 250 mL. The order is 12 units/kg/h for a patient who weighs 72 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/250 mL12 units/kg/h72 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine9 mL/h100 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dobutamine infusion of 500 mg in 250 mL runs at 9 mL/h. The patient weighs 100 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

500 mg/250 mL9 mL/h100 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjelly120 mLtea200 mLwater120 mLice chips100 mLIV infusion80 mL/h × 8 hIV antibiotic2 × 100 mLurine500 mLurine425 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

jelly: 120 mLtea: 200 mLwater: 120 mLice chips: 100 mLIV infusion: 80 mL/h × 8 hIV antibiotic: 2 × 100 mLurine: 500 mLurine: 425 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL200 mL infused120 mL/h06:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 120 mL/h. At 06:00, 200 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL200 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
10 lb 14 oz? kg1 lb = 16 oz1 kg = 2.2 lb

Practice exercise (made-up values, not clinical guidance). A newborn weighs 10 lb 14 oz. Using 1 lb = 16 oz and 1 kg = 2.2 lb, find the weight m in kilograms. Round to two decimal places.

10 lb 14 oz1 lb = 16 oz1 kg = 2.2 lb
m = kg
10.Nursing math & unit conversionsHard
2 tsp · 2/day · 10 d? mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 2 tsp of an oral suspension twice a day for 10 days. Using 1 tsp = 5 mL, how many mL V are needed for the whole course?

2 tsptwice a day10 days1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 4.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 10·23 = 230 mg

Volume

V = 230/50 = 4.6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 4.6 mL
2.Dosage calculations

Answer: V = 0.5 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

4 mg/mL = 4000 mcg/mL

Volume

V = 2000/4000 = 0.5 mL

Answer

V = 0.5 mL
3.IV infusion rates

Answer: R = 60 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Millilitres per minute

60/60 = 1 mL/min

Drip rate

R = 1·60 = 60 gtt/min

Answer

R = 60 gtt/min

With a microdrip set (60 gtt/mL), gtt/min equals mL/h.

4.IV infusion rates

Answer: t = 5 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/20 = 120 mL/h

Time left

t = 600/120 = 5 h

Answer

t = 5 h
5.Pediatric & critical-care dosing

Answer: R = 8.6 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

12·72 = 864 units/h

Concentration

25 000/250 = 100 units/mL

Pump rate

R = 864/100 = 8.64 ≈ 8.6 mL/h

Answer

R = 8.6 mL/h
6.Pediatric & critical-care dosing

Answer: D = 3 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 000/250 = 2000 mcg/mL

Micrograms per minute

9·2000 = 18000 mcg/h
18000/60 = 300 mcg/min

Per kilogram

D = 300/100 = 3 mcg/kg/min

Answer

D = 3 mcg/kg/min
7.IV fluids & fluid balance

Answer: B = 405 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 120 + 200 + 120 = 440 mL
ice chips: 100/2 = 50 mL
IV infusion: 80·8 = 640 mL
IV antibiotic: 2·100 = 200 mL
total intake = 1330 mL

Total output

500 + 425 = 925 mL

Balance

B = 1330 − 925 = 405 mL

Answer

B = 405 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 6.7 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 200 = 800 mL

Time

t = 800/120 = 6.667 ≈ 6.7 h

Answer

t = 6.7 h

That is about 6 h 40 min, so the bag runs out at about 12:40.

9.Nursing math & unit conversions

Answer: m = 4.94 kg

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Ounces to pounds

14 oz/16 = 0.875 lb
10 + 0.875 = 10.88 lb

Pounds to kilograms

m = 10.88/2.2 = 4.943 ≈ 4.94 kg

Answer

m = 4.94 kg
10.Nursing math & unit conversions

Answer: V = 200 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

2 tsp = 2·5 = 10 mL

Whole course

V = 10 mL × 2/day × 10 = 200 mL

Answer

V = 200 mL

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