NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 26 kg is prescribed 2 mg/kg of a drug. The stock solution contains 10 mg/mL. Draw up the dose: what volume V do you give?

26 kg2 mg/kg10 mg/mL
V = mL
2.Dosage calculationsHard
25k units250 mL? mL/h500 units/h

An infusion contains 25000 units of a drug in 250 mL. The prescription is 500 units per hour. At what rate R do you set the pump, in mL/h?

25000 units/250 mL500 units/h
R = mL/h
3.IV infusion ratesMedium
1000 mL10 gtt/mL12 h? gtt/min

Infuse 1000 mL over 12 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL12 h10 gtt/mL
R = gtt/min
4.IV infusion ratesHard
200 mg250 mL20 mL/h? mg/h

A bag contains 200 mg of a drug in 250 mL and runs at 20 mL/h. How many milligrams per hour D does the patient receive?

200 mg/250 mL20 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
100 units250 mLregular insulin? mL/h58 kg0.05 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 250 mL. The order is 0.05 units/kg/h for a patient who weighs 58 kg. Find the pump rate R in mL/h. Round to one decimal place.

100 units/250 mL0.05 units/kg/h58 kg
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h57 kg5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 5 mcg/kg/min for a patient who weighs 57 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL5 mcg/kg/min57 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftwater200 mLtea150 mLmilk200 mLice chips100 mLIV infusion125 mL/h × 12 hIV antibiotic1 × 50 mLurine350 mLurine275 mLurine425 mLurine400 mLwound drain40 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 59 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

59 kg12 hurine: 350 mLurine: 275 mLurine: 425 mLurine: 400 mLwound drain: 40 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL→ 200 mL/hstart 16:30ttotal​ = ? h80 mL/h × 2 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 16:30 at 80 mL/h. After 2 hours the rate is changed to 200 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL80 mL/h · 2 h200 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C? °F39.9 °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 39.9 °C. Convert it to degrees Fahrenheit T with °F = °C × 9/5 + 32. Round to one decimal place.

39.9 °C
T = °F
10.Nursing math & unit conversionsHard
10 mcg/min? mg/h1 h = 60 min1 mg = 1000 mcg

Practice exercise (made-up values, not clinical guidance). An infusion delivers 10 mcg/min. Express this dose rate D in mg/h.

10 mcg/min1 h = 60 min1 mg = 1000 mcg
D = mg/h

3Solutions

1.Dosage calculations

Answer: V = 5.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 2·26 = 52 mg

Volume

V = 52/10 = 5.2 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 5.2 mL
2.Dosage calculations

Answer: R = 5 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

25000/250 = 100 units/mL

Pump rate

R = 500/100 = 5 mL/h

Answer

R = 5 mL/h
3.IV infusion rates

Answer: R = 14 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

12·60 = 720 min

Drip rate

R = 1000·10/720 = 13.89 ≈ 14 gtt/min

Answer

R = 14 gtt/min

At the bedside you round to the nearest whole drop: 14 gtt/min.

4.IV infusion rates

Answer: D = 16 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

200/250 = 0.8 mg/mL

Dose rate

D = 0.8·20 = 16 mg/h

Answer

D = 16 mg/h
5.Pediatric & critical-care dosing

Answer: R = 7.3 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.05·58 = 2.9 units/h

Concentration

100/250 = 0.4 units/mL

Pump rate

R = 2.9/0.4 = 7.25 ≈ 7.3 mL/h

Answer

R = 7.3 mL/h
6.Pediatric & critical-care dosing

Answer: R = 17.1 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

5·57 = 285 mcg/min
285·60 = 17100 mcg/h

Pump rate

R = 17100/1000 = 17.1 mL/h

Answer

R = 17.1 mL/h
7.IV fluids & fluid balance

Answer: U = 2.05 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

350 + 275 + 425 + 400 = 1450 mL

Per kilogram per hour

U = 1450/(59·12) = 2.048 ≈ 2.05 mL/kg/h

Answer

U = 2.05 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 6.2 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

80·2 = 160 mL
1000 − 160 = 840 mL left

Second part

840/200 = 4.2 h

Total time

t = 2 + 4.2 = 6.2 h

Answer

t = 6.2 h

That is about 6 h 12 min, so the bag runs out at about 22:42.

9.Nursing math & unit conversions

Answer: T = 103.8 °F

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Multiply by 9/5

39.9·9/5 = 71.82

Add 32

T = 71.82 + 32 = 103.8 °F

Answer

T = 103.8 °F
10.Nursing math & unit conversions

Answer: D = 0.6 mg/h

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 10 mcg/min × (60 min/1 h) × (1 mg/1000 mcg)

Calculate

D = 10·60/1000 = 0.6 mg/h

Answer

D = 0.6 mg/h

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