NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
5%w/vV = ? mL

A dose of 500 mg is needed from a 5% (w/v) solution. What volume V contains this dose?

500 mg5% w/v
V = mL
2.Dosage calculationsHard
25%stockwater = ? mL

You must prepare 500 mL of a 2.5% (w/v) solution from a 25% (w/v) stock solution. How much water W must be added to the stock?

C₁ = 25%C₂ = 2.5%V₂ = 500 mL
W = mL
3.IV infusion ratesMedium
V = ?15 gtt/mL40 gtt/min3 h

A drip runs at 40 gtt/min through a set of 15 gtt/mL. How many millilitres V does the patient receive in 3 hours?

40 gtt/min15 gtt/mL3 h
V = mL
4.IV infusion ratesHard
1 g250 mL? mL/h4 mg/min

A bag contains 1 g of a drug in 250 mL. The order is 4 mg per minute. At what rate R do you set the pump, in mL/h?

1 g/250 mL4 mg/min
R = mL/h
5.Pediatric & critical-care dosingMedium
100 units250 mLregular insulin? mL/h95 kg0.1 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 250 mL. The order is 0.1 units/kg/h for a patient who weighs 95 kg. Find the pump rate R in mL/h. Round to one decimal place.

100 units/250 mL0.1 units/kg/h95 kg
R = mL/h
6.Pediatric & critical-care dosingHard
50 mg250 mLnitroglycerin? mL/h77 kg15 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 77 kg has an order for nitroglycerin at 15 mcg/min. The bag contains 50 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

50 mg/250 mL15 mcg/min77 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftsoup180 mLtea240 mLmilk100 mLIV infusion125 mL/h × 12 hIV antibiotic1 × 100 mLurine175 mLurine250 mLurine250 mLurine500 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

soup: 180 mLtea: 240 mLmilk: 100 mLIV infusion: 125 mL/h × 12 hIV antibiotic: 1 × 100 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL→ 80 mL/hstart 13:30ttotal​ = ? h75 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 13:30 at 75 mL/h. After 4 hours the rate is changed to 80 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL75 mL/h · 4 h80 mL/h
t = h
9.Nursing math & unit conversionsMedium
1234567891011122:50 AM?14:5001:5003:5002:50

Practice exercise (made-up values, not clinical guidance). A dose is charted at 2:50 AM. Which entry is the same time on the 24-hour clock? Click it.

2:50 AM
  1. 114:50
  2. 201:50
  3. 303:50
  4. 402:50
10.Nursing math & unit conversionsHard
1½ tbsp? mL2 cups? mL2 tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 1½ tbsp of liquid supplement, 2 cups of tea, 2 tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 10 mL

Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.

Concentration

5% = 50 mg/mL

Volume

V = 500/50 = 10 mL

Answer

V = 10 mL
2.Dosage calculations

Answer: W = 450 mL

Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.

Volume of stock

V₁ = 2.5·500/25 = 50 mL

Water to add

W = 500 − 50 = 450 mL

Answer

W = 450 mL
3.IV infusion rates

Answer: V = 480 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/15 = 160 mL/h

Volume

V = 160·3 = 480 mL

Answer

V = 480 mL
4.IV infusion rates

Answer: R = 60 mL/h

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000 mg/250 mL = 4 mg/mL

Dose per hour

4·60 = 240 mg/h

Pump rate

R = 240/4 = 60 mL/h

Answer

R = 60 mL/h
5.Pediatric & critical-care dosing

Answer: R = 23.8 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.1·95 = 9.5 units/h

Concentration

100/250 = 0.4 units/mL

Pump rate

R = 9.5/0.4 = 23.75 ≈ 23.8 mL/h

Answer

R = 23.8 mL/h
6.Pediatric & critical-care dosing

Answer: R = 4.5 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50 000/250 = 200 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

15·60 = 900 mcg/h

Pump rate

R = 900/200 = 4.5 mL/h

Answer

R = 4.5 mL/h
7.IV fluids & fluid balance

Answer: I = 2120 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 180 + 240 + 100 = 520 mL
IV infusion: 125·12 = 1500 mL
IV antibiotic: 1·100 = 100 mL
I = 2120 mL

Answer

I = 2120 mL
8.IV fluids & fluid balance

Answer: t = 12.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·4 = 300 mL
1000 − 300 = 700 mL left

Second part

700/80 = 8.75 h

Total time

t = 4 + 8.75 = 12.75 ≈ 12.8 h

Answer

t = 12.8 h

That is about 12 h 45 min, so the bag runs out at about 02:15.

9.Nursing math & unit conversions

Answer: 02:50

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

2 AM → 02

Answer

02:50

Answer

02:50
10.Nursing math & unit conversions

Answer: V = 512.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

1½ tbsp = 1.5·15 = 22.5 mL
2 cups = 2·240 = 480 mL
2 tsp = 2·5 = 10 mL

Add

V = 22.5 + 480 + 10 = 512.5 mL

Answer

V = 512.5 mL

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