NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 22 kg is prescribed 5 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

22 kg5 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
31 kg127 cmBSA = √(h·w/3600)25 mg/m²D = ? mg

A patient is 127 cm tall and weighs 31 kg. The prescription is 25 mg/m². Using the Mosteller formula BSA = √(height (cm) × weight (kg)/3600), find the dose D in mg.

127 cm31 kg25 mg/m²
D = mg
3.IV infusion ratesMedium
500 mL15 gtt/mL2 h? gtt/min

Infuse 500 mL over 2 hours with a giving set of 15 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL2 h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
300 mL20 gtt/mL25 gtt/mint = ? h

A drip runs at 25 gtt/min through a set of 20 gtt/mL. There are 300 mL left in the bag. How many hours t until it is empty?

25 gtt/min20 gtt/mL300 mL
t = h
5.Pediatric & critical-care dosingMedium
25 000 units500 mLheparin? mL/h99 kg14 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 500 mL. The order is 14 units/kg/h for a patient who weighs 99 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/500 mL14 units/kg/h99 kg
R = mL/h
6.Pediatric & critical-care dosingHard
8 mg250 mLnorepinephrine? mL/h93 kg12 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 93 kg has an order for norepinephrine at 12 mcg/min. The bag contains 8 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

8 mg/250 mL12 mcg/min93 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftsoup150 mLjelly100 mLice chips240 mLIV infusion100 mL/h × 12 hIV antibiotic1 × 100 mLurine375 mLurine150 mLurine175 mLwound drain50 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

soup: 150 mLjelly: 100 mLice chips: 240 mLIV infusion: 100 mL/h × 12 hIV antibiotic: 1 × 100 mLurine: 375 mLurine: 150 mLurine: 175 mLwound drain: 50 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL60 mL/hstart 13:0019:00: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 13:00 and runs by pump at 60 mL/h. How many mL V are left in the bag at 19:00?

1000 mL60 mL/h13:00 → 19:00
V = mL
9.Nursing math & unit conversionsMedium
12345678910111223:40?10:40 PM11:40 PM11:40 AM1:40 PM

Practice exercise (made-up values, not clinical guidance). A dose is charted at 23:40 (24-hour clock). Which entry is the same time on the 12-hour clock? Click it.

23:40
  1. 110:40 PM
  2. 211:40 PM
  3. 311:40 AM
  4. 41:40 PM
10.Nursing math & unit conversionsHard
3 fl oz? mL½ tbsp? mL¼ cup? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 3 fl oz of juice, ½ tbsp of liquid supplement, ¼ cup of tea. Using the equivalents given, find the total oral intake V in mL.

1 fl oz = 30 mL1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 2.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·22 = 110 mg

Volume

V = 110/50 = 2.2 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 2.2 mL
2.Dosage calculations

Answer: D = 26.14 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Body surface area

BSA = √(127·31/3600) = √1.094 = 1.046 m²

Dose

D = 25·1.046 = 26.14 mg

Answer

D = 26.14 mg
3.IV infusion rates

Answer: R = 63 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

2·60 = 120 min

Drip rate

R = 500·15/120 = 62.5 ≈ 63 gtt/min

Answer

R = 63 gtt/min

At the bedside you round to the nearest whole drop: 63 gtt/min.

4.IV infusion rates

Answer: t = 4 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

25·60/20 = 75 mL/h

Time left

t = 300/75 = 4 h

Answer

t = 4 h
5.Pediatric & critical-care dosing

Answer: R = 27.7 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

14·99 = 1 386 units/h

Concentration

25 000/500 = 50 units/mL

Pump rate

R = 1386/50 = 27.72 ≈ 27.7 mL/h

Answer

R = 27.7 mL/h
6.Pediatric & critical-care dosing

Answer: R = 22.5 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

8 000/250 = 32 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

12·60 = 720 mcg/h

Pump rate

R = 720/32 = 22.5 mL/h

Answer

R = 22.5 mL/h
7.IV fluids & fluid balance

Answer: B = 920 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 150 + 100 = 250 mL
ice chips: 240/2 = 120 mL
IV infusion: 100·12 = 1200 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1670 mL

Total output

375 + 150 + 175 + 50 = 750 mL

Balance

B = 1670 − 750 = 920 mL

Answer

B = 920 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: V = 640 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

13:00 → 19:00 = 6 h

Volume infused

60·6 = 360 mL

Volume left

V = 1000 − 360 = 640 mL

Answer

V = 640 mL
9.Nursing math & unit conversions

Answer: 11:40 PM

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

23 − 12 = 11 → PM

Answer

11:40 PM

Answer

11:40 PM
10.Nursing math & unit conversions

Answer: V = 157.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

3 fl oz = 3·30 = 90 mL
½ tbsp = 0.5·15 = 7.5 mL
¼ cup = 0.25·240 = 60 mL

Add

V = 90 + 7.5 + 60 = 157.5 mL

Answer

V = 157.5 mL

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