NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
22 kg15 mg/kgD = ? mg

A patient weighs 22 kg and is prescribed 15 mg/kg as a single dose. Find the dose D in mg.

22 kg15 mg/kg
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 1880 micrograms. The ampoule contains 2 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

1880 mcg2 mg/mL
V = mL
3.IV infusion ratesMedium
250 mL60 gtt/mL3 h? gtt/min

Infuse 250 mL over 3 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

250 mL3 h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
1000 mg50 mL15 mL/h? mg/h

A bag contains 1000 mg of a drug in 50 mL and runs at 15 mL/h. How many milligrams per hour D does the patient receive?

1000 mg/50 mL15 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL80 units/kg · 59 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 80 units/kg for a patient who weighs 59 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

80 units/kg59 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine? mL/h71 kg5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 800 mg in 500 mL. The order is 5 mcg/kg/min for a patient who weighs 71 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

800 mg/500 mL5 mcg/kg/min71 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftsoup250 mLtea150 mLjelly100 mLIV infusion80 mL/h × 8 hIV antibiotic2 × 100 mLurine325 mLurine450 mLwound drain60 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 64 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

64 kg8 hurine: 325 mLurine: 450 mLwound drain: 60 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL250 mL infused50 mL/h13:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 50 mL/h. At 13:00, 250 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL250 mL infused50 mL/h
t = h
9.Nursing math & unit conversionsMedium
4.9775 mL? mLround to 0.1 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for an injection gives 4.9775 mL. The rule in this exercise is that volumes of 1 mL or more are rounded to the nearest tenth of a mL. What value x do you record?

4.9775 mL
x = mL
10.Nursing math & unit conversionsHard
1 tbsp · 2/day · 7 d? mL1 tbsp = 15 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 1 tbsp of an oral suspension every 12 hours for 7 days. Using 1 tbsp = 15 mL, how many mL V are needed for the whole course?

1 tbspevery 12 hours7 days1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 330 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose

15·22 = 330 mg

Answer

D = 330 mg
2.Dosage calculations

Answer: V = 0.94 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

2 mg/mL = 2000 mcg/mL

Volume

V = 1880/2000 = 0.94 mL

Answer

V = 0.94 mL
3.IV infusion rates

Answer: R = 83 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

3·60 = 180 min

Drip rate

R = 250·60/180 = 83.33 ≈ 83 gtt/min

Answer

R = 83 gtt/min

At the bedside you round to the nearest whole drop: 83 gtt/min.

4.IV infusion rates

Answer: D = 300 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

1000/50 = 20 mg/mL

Dose rate

D = 20·15 = 300 mg/h

Answer

D = 300 mg/h
5.Pediatric & critical-care dosing

Answer: V = 4.7 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

80·59 = 4 720 units

Volume

V = 4720/1000 = 4.72 ≈ 4.7 mL

Answer

V = 4.7 mL
6.Pediatric & critical-care dosing

Answer: R = 13.3 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 mg = 800 000 mcg
800 000/500 = 1600 mcg/mL

Dose per minute and per hour

5·71 = 355 mcg/min
355·60 = 21300 mcg/h

Pump rate

R = 21300/1600 = 13.31 ≈ 13.3 mL/h

Answer

R = 13.3 mL/h
7.IV fluids & fluid balance

Answer: U = 1.51 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

325 + 450 = 775 mL

Per kilogram per hour

U = 775/(64·8) = 1.514 ≈ 1.51 mL/kg/h

Answer

U = 1.51 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 15 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 250 = 750 mL

Time

t = 750/50 = 15 h

Answer

t = 15 h

That is about 15 h 00 min, so the bag runs out at about 04:00.

9.Nursing math & unit conversions

Answer: x = 5 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

4.9775 → 9

Only the next digit decides

4.9775 → 7
7 is 5 or more, so round 9 up.
The digits after it (75) are ignored: round once, never step by step.

Round

x = 5 mL

Answer

x = 5 mL
10.Nursing math & unit conversions

Answer: V = 210 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

1 tbsp = 1·15 = 15 mL

Whole course

V = 15 mL × 2/day × 7 = 210 mL

Answer

V = 210 mL

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