NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 8 kg is prescribed 2 mg/kg of a drug. The stock solution contains 10 mg/mL. Draw up the dose: what volume V do you give?

8 kg2 mg/kg10 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 1460 micrograms. The ampoule contains 2 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

1460 mcg2 mg/mL
V = mL
3.IV infusion ratesMedium
1000 mL10 gtt/mL8 h? gtt/min

Infuse 1000 mL over 8 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL8 h10 gtt/mL
R = gtt/min
4.IV infusion ratesHard
4 g500 mL? mL/h4 mg/min

A bag contains 4 g of a drug in 500 mL. The order is 4 mg per minute. At what rate R do you set the pump, in mL/h?

4 g/500 mL4 mg/min
R = mL/h
5.Pediatric & critical-care dosingMedium
heparin 5 000 units/mL60 units/kg · 106 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 106 kg. The vial contains 5 000 units/mL. What volume V do you draw up? Round to one decimal place.

60 units/kg106 kg5 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
8 mg250 mLnorepinephrine? mL/h98 kg16 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 98 kg has an order for norepinephrine at 16 mcg/min. The bag contains 8 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

8 mg/250 mL16 mcg/min98 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLjelly100 mLice chips120 mLIV infusion125 mL/h × 12 hIV antibiotic2 × 50 mLurine475 mLurine225 mLwound drain120 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL. Count ice chips as half their volume.

tea: 240 mLjelly: 100 mLice chips: 120 mLIV infusion: 125 mL/h × 12 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
500 mL125 mL/hstart 08:0011:00: ? mL

Practice exercise (made-up values, not clinical guidance). A 500 mL bag was started at 08:00 and runs by pump at 125 mL/h. How many mL V are left in the bag at 11:00?

500 mL125 mL/h08:00 → 11:00
V = mL
9.Nursing math & unit conversionsMedium
4 ft 11 in1 ft = 12 in1 in = 2.54 cmh = ? cm

Practice exercise (made-up values, not clinical guidance). A patient is 4 ft 11 in tall. Using 1 ft = 12 in and 1 in = 2.54 cm, find the height h in centimetres, to the nearest whole centimetre.

4 ft 11 in1 ft = 12 in1 in = 2.54 cm
h = cm
10.Nursing math & unit conversionsHard
00:0017:3001:45t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 17:30 and finishes at 01:45 the next morning (24-hour clock). How many minutes t did it run?

17:3001:45
t = min

3Solutions

1.Dosage calculations

Answer: V = 1.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 2·8 = 16 mg

Volume

V = 16/10 = 1.6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 1.6 mL
2.Dosage calculations

Answer: V = 0.73 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

2 mg/mL = 2000 mcg/mL

Volume

V = 1460/2000 = 0.73 mL

Answer

V = 0.73 mL
3.IV infusion rates

Answer: R = 21 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 1000·10/480 = 20.83 ≈ 21 gtt/min

Answer

R = 21 gtt/min

At the bedside you round to the nearest whole drop: 21 gtt/min.

4.IV infusion rates

Answer: R = 30 mL/h

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

4000 mg/500 mL = 8 mg/mL

Dose per hour

4·60 = 240 mg/h

Pump rate

R = 240/8 = 30 mL/h

Answer

R = 30 mL/h
5.Pediatric & critical-care dosing

Answer: V = 1.3 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·106 = 6 360 units

Volume

V = 6360/5000 = 1.272 ≈ 1.3 mL

Answer

V = 1.3 mL
6.Pediatric & critical-care dosing

Answer: R = 30 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

8 000/250 = 32 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

16·60 = 960 mcg/h

Pump rate

R = 960/32 = 30 mL/h

Answer

R = 30 mL/h
7.IV fluids & fluid balance

Answer: I = 2000 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 240 + 100 = 340 mL
ice chips: 120/2 = 60 mL
IV infusion: 125·12 = 1500 mL
IV antibiotic: 2·50 = 100 mL
I = 2000 mL

Answer

I = 2000 mL
8.IV fluids & fluid balance

Answer: V = 125 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

08:00 → 11:00 = 3 h

Volume infused

125·3 = 375 mL

Volume left

V = 500 − 375 = 125 mL

Answer

V = 125 mL
9.Nursing math & unit conversions

Answer: h = 150 cm

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Height in inches

4·12 + 11 = 59 in

Inches to centimetres

h = 59·2.54 = 149.9 ≈ 150 cm

Answer

h = 150 cm
10.Nursing math & unit conversions

Answer: t = 495 min

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

17:30 → 24:00 = 390 min

After midnight

00:00 → 01:45 = 105 min

Total

t = 390 + 105 = 495 min

Answer

t = 495 min

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