NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 20 kg is prescribed 4 mg/kg of a drug. The stock solution contains 20 mg/mL. Draw up the dose: what volume V do you give?

20 kg4 mg/kg20 mg/mL
V = mL
2.Dosage calculationsHard
40k units250 mL? mL/h1200 units/h

An infusion contains 40000 units of a drug in 250 mL. The prescription is 1200 units per hour. At what rate R do you set the pump, in mL/h?

40000 units/250 mL1200 units/h
R = mL/h
3.IV infusion ratesMedium
250 mL60 gtt/mL10 h? gtt/min

Infuse 250 mL over 10 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute.

250 mL10 h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
400 mL20 gtt/mL40 gtt/mint = ? h

A drip runs at 40 gtt/min through a set of 20 gtt/mL. There are 400 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

40 gtt/min20 gtt/mL400 mL
t = h
5.Pediatric & critical-care dosingMedium
100 units100 mLregular insulin? mL/h98 kg0.05 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 100 mL. The order is 0.05 units/kg/h for a patient who weighs 98 kg. Find the pump rate R in mL/h. Round to one decimal place.

100 units/100 mL0.05 units/kg/h98 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine? mL/h69 kg12.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 500 mg in 250 mL. The order is 12.5 mcg/kg/min for a patient who weighs 69 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

500 mg/250 mL12.5 mcg/kg/min69 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjelly120 mLtea150 mLsoup250 mLice chips240 mLIV infusion75 mL/h × 8 hIV antibiotic1 × 100 mLurine225 mLurine225 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

jelly: 120 mLtea: 150 mLsoup: 250 mLice chips: 240 mLIV infusion: 75 mL/h × 8 hIV antibiotic: 1 × 100 mLurine: 225 mLurine: 225 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL50 mL infused125 mL/h16:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 125 mL/h. At 16:30, 50 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL50 mL infused125 mL/h
t = h
9.Nursing math & unit conversionsMedium
117.594 gtt/min? gtt/minround to 1 gtt/min

Practice exercise (made-up values, not clinical guidance). A drip-rate calculation gives 117.594 gtt/min. The rule in this exercise is that drip rates are rounded to the nearest whole drop. What value x do you record?

117.594 gtt/min
x = gtt/min
10.Nursing math & unit conversionsHard
13.9 g/dL? g/L1 L = 10 dL

Practice exercise (made-up values, not clinical guidance). A haemoglobin result is 13.9 g/dL. Express it in g/L Hb.

13.9 g/dL1 L = 10 dL
Hb = g/L

3Solutions

1.Dosage calculations

Answer: V = 4 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 4·20 = 80 mg

Volume

V = 80/20 = 4 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 4 mL
2.Dosage calculations

Answer: R = 7.5 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

40000/250 = 160 units/mL

Pump rate

R = 1200/160 = 7.5 mL/h

Answer

R = 7.5 mL/h
3.IV infusion rates

Answer: R = 25 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

10·60 = 600 min

Drip rate

R = 250·60/600 = 25 gtt/min

Answer

R = 25 gtt/min
4.IV infusion rates

Answer: t = 3.3 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/20 = 120 mL/h

Time left

t = 400/120 = 3.333 ≈ 3.3 h

Answer

t = 3.3 h
5.Pediatric & critical-care dosing

Answer: R = 4.9 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.05·98 = 4.9 units/h

Concentration

100/100 = 1 units/mL

Pump rate

R = 4.9/1 = 4.9 mL/h

Answer

R = 4.9 mL/h
6.Pediatric & critical-care dosing

Answer: R = 25.9 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 mg = 500 000 mcg
500 000/250 = 2000 mcg/mL

Dose per minute and per hour

12.5·69 = 862.5 mcg/min
862.5·60 = 51750 mcg/h

Pump rate

R = 51750/2000 = 25.88 ≈ 25.9 mL/h

Answer

R = 25.9 mL/h
7.IV fluids & fluid balance

Answer: B = 890 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 120 + 150 + 250 = 520 mL
ice chips: 240/2 = 120 mL
IV infusion: 75·8 = 600 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1340 mL

Total output

225 + 225 = 450 mL

Balance

B = 1340 − 450 = 890 mL

Answer

B = 890 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 7.6 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 50 = 950 mL

Time

t = 950/125 = 7.6 h

Answer

t = 7.6 h

That is about 7 h 36 min, so the bag runs out at about 00:06.

9.Nursing math & unit conversions

Answer: x = 118 gtt/min

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the ones place

117.594 → 7

Only the next digit decides

117.594 → 5
5 is 5 or more, so round 7 up.
The digits after it (94) are ignored: round once, never step by step.

Round

x = 118 gtt/min

Answer

x = 118 gtt/min
10.Nursing math & unit conversions

Answer: Hb = 139 g/L

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Convert

Hb = 13.9 g/dL × 10 dL/L = 139 g/L

Answer

Hb = 139 g/L

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