NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
500 mg+ 4.6 mLV = ? mL

A vial contains 500 mg of powder. The label says: add 4.6 mL of water for injection to give a total volume of 5 mL. The prescription is 40 mg. What volume V of the reconstituted solution do you give?

500 mg+ 4.6 mL → 5 mL40 mg
V = mL
2.Dosage calculationsHard
25k units1000 mL? mL/h1250 units/h

An infusion contains 25000 units of a drug in 1000 mL. The prescription is 1250 units per hour. At what rate R do you set the pump, in mL/h?

25000 units/1000 mL1250 units/h
R = mL/h
3.IV infusion ratesMedium
500 mL20 gtt/mL8 h? gtt/min

Infuse 500 mL over 8 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL8 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
400 mg500 mL20 mL/h? mg/h

A bag contains 400 mg of a drug in 500 mL and runs at 20 mL/h. How many milligrams per hour D does the patient receive?

400 mg/500 mL20 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL70 units/kg · 85 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 70 units/kg for a patient who weighs 85 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

70 units/kg85 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
400 mg250 mLdopamine? mL/h83 kg12 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 400 mg in 250 mL. The order is 12 mcg/kg/min for a patient who weighs 83 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

400 mg/250 mL12 mcg/kg/min83 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLmilk240 mLsoup150 mLice chips120 mLIV infusion80 mL/h × 12 hIV antibiotic2 × 50 mLurine225 mLurine350 mLurine250 mLurine350 mLwound drain110 mLvomit250 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

tea: 240 mLmilk: 240 mLsoup: 150 mLice chips: 120 mLIV infusion: 80 mL/h × 12 hIV antibiotic: 2 × 50 mLurine: 225 mLurine: 350 mLurine: 250 mLurine: 350 mLwound drain: 110 mLvomit: 250 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL120 mL/hstart 07:0014:00: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 07:00 and runs by pump at 120 mL/h. How many mL V are left in the bag at 14:00?

1000 mL120 mL/h07:00 → 14:00
V = mL
9.Nursing math & unit conversionsMedium
6 ft 11 in1 ft = 12 in1 in = 2.54 cmh = ? cm

Practice exercise (made-up values, not clinical guidance). A patient is 6 ft 11 in tall. Using 1 ft = 12 in and 1 in = 2.54 cm, find the height h in centimetres, to the nearest whole centimetre.

6 ft 11 in1 ft = 12 in1 in = 2.54 cm
h = cm
10.Nursing math & unit conversionsHard
15.6 mmol/L? mg/dL1 mmol/L = 18 mg/dL

Practice exercise (made-up values, not clinical guidance). A blood glucose result is 15.6 mmol/L. Using 1 mmol/L = 18 mg/dL for glucose, find c in mg/dL to the nearest whole number.

15.6 mmol/L1 mmol/L = 18 mg/dL
c = mg/dL

3Solutions

1.Dosage calculations

Answer: V = 0.4 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration after mixing

500 mg/5 mL = 100 mg/mL

Volume

V = 40/100 = 0.4 mL

Answer

V = 0.4 mL
2.Dosage calculations

Answer: R = 50 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

25000/1000 = 25 units/mL

Pump rate

R = 1250/25 = 50 mL/h

Answer

R = 50 mL/h
3.IV infusion rates

Answer: R = 21 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 500·20/480 = 20.83 ≈ 21 gtt/min

Answer

R = 21 gtt/min

At the bedside you round to the nearest whole drop: 21 gtt/min.

4.IV infusion rates

Answer: D = 16 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

400/500 = 0.8 mg/mL

Dose rate

D = 0.8·20 = 16 mg/h

Answer

D = 16 mg/h
5.Pediatric & critical-care dosing

Answer: V = 6 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

70·85 = 5 950 units

Volume

V = 5950/1000 = 5.95 ≈ 6 mL

Answer

V = 6 mL
6.Pediatric & critical-care dosing

Answer: R = 37.4 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

400 mg = 400 000 mcg
400 000/250 = 1600 mcg/mL

Dose per minute and per hour

12·83 = 996 mcg/min
996·60 = 59760 mcg/h

Pump rate

R = 59760/1600 = 37.35 ≈ 37.4 mL/h

Answer

R = 37.4 mL/h
7.IV fluids & fluid balance

Answer: B = 215 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 240 + 240 + 150 = 630 mL
ice chips: 120/2 = 60 mL
IV infusion: 80·12 = 960 mL
IV antibiotic: 2·50 = 100 mL
total intake = 1750 mL

Total output

225 + 350 + 250 + 350 + 110 + 250 = 1535 mL

Balance

B = 1750 − 1535 = 215 mL

Answer

B = 215 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: V = 160 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

07:00 → 14:00 = 7 h

Volume infused

120·7 = 840 mL

Volume left

V = 1000 − 840 = 160 mL

Answer

V = 160 mL
9.Nursing math & unit conversions

Answer: h = 211 cm

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Height in inches

6·12 + 11 = 83 in

Inches to centimetres

h = 83·2.54 = 210.8 ≈ 211 cm

Answer

h = 211 cm
10.Nursing math & unit conversions

Answer: c = 281 mg/dL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Convert

c = 15.6·18 = 280.8 ≈ 281 mg/dL

Answer

c = 281 mg/dL

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