NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
13 kgBSA = 0.64 m²100 mg/m²D = ? mg

A patient weighing 13 kg has a body surface area of 0.64 m². The prescription is 100 mg/m². Find the dose D in mg.

13 kgBSA = 0.64 m²100 mg/m²
D = mg
2.Dosage calculationsHard
20k units250 mL? mL/h2000 units/h

An infusion contains 20000 units of a drug in 250 mL. The prescription is 2000 units per hour. At what rate R do you set the pump, in mL/h?

20000 units/250 mL2000 units/h
R = mL/h
3.IV infusion ratesMedium
1000 mL10 gtt/mL8 h? gtt/min

Infuse 1000 mL over 8 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL8 h10 gtt/mL
R = gtt/min
4.IV infusion ratesHard
200 mg100 mL15 gtt/mL40 mg/h? gtt/min

200 mg of a drug is diluted in 100 mL and given by gravity through a set of 15 gtt/mL. The order is 40 mg per hour. Find the drip rate R in drops per minute.

200 mg/100 mL40 mg/h15 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
20 000 units500 mLheparin? mL/h104 kg18 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 20 000 units of heparin in 500 mL. The order is 18 units/kg/h for a patient who weighs 104 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

20 000 units/500 mL18 units/kg/h104 kg
R = mL/h
6.Pediatric & critical-care dosingHard
50 mg250 mLnitroglycerin? mL/h71 kg40 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 71 kg has an order for nitroglycerin at 40 mcg/min. The bag contains 50 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

50 mg/250 mL40 mcg/min71 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater240 mLmilk100 mLIV infusion125 mL/h × 8 hIV antibiotic2 × 100 mLurine200 mLurine500 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

water: 240 mLmilk: 100 mLIV infusion: 125 mL/h × 8 hIV antibiotic: 2 × 100 mLurine: 200 mLurine: 500 mLvomit: 100 mL
B = mL
8.IV fluids & fluid balanceHard
500 mL200 mL infused120 mL/h07:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 120 mL/h. At 07:30, 200 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL200 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
6 ft 3 in1 ft = 12 in1 in = 2.54 cmh = ? cm

Practice exercise (made-up values, not clinical guidance). A patient is 6 ft 3 in tall. Using 1 ft = 12 in and 1 in = 2.54 cm, find the height h in centimetres, to the nearest whole centimetre.

6 ft 3 in1 ft = 12 in1 in = 2.54 cm
h = cm
10.Nursing math & unit conversionsHard
½ tsp? mL½ tbsp? mL3 cups? mL1½ fl oz? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes ½ tsp of cough syrup, ½ tbsp of liquid supplement, 3 cups of tea, 1½ fl oz of juice. Using the equivalents given, find the total oral intake V in mL.

1 tsp = 5 mL1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 64 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Dose

D = 100·0.64 = 64 mg

Answer

D = 64 mg
2.Dosage calculations

Answer: R = 25 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

20000/250 = 80 units/mL

Pump rate

R = 2000/80 = 25 mL/h

Answer

R = 25 mL/h
3.IV infusion rates

Answer: R = 21 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 1000·10/480 = 20.83 ≈ 21 gtt/min

Answer

R = 21 gtt/min

At the bedside you round to the nearest whole drop: 21 gtt/min.

4.IV infusion rates

Answer: R = 5 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

200/100 = 2 mg/mL

Volume per hour

40/2 = 20 mL/h

Drip rate

R = 20·15/60 = 5 gtt/min

Answer

R = 5 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 46.8 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

18·104 = 1 872 units/h

Concentration

20 000/500 = 40 units/mL

Pump rate

R = 1872/40 = 46.8 mL/h

Answer

R = 46.8 mL/h
6.Pediatric & critical-care dosing

Answer: R = 12 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50 000/250 = 200 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

40·60 = 2400 mcg/h

Pump rate

R = 2400/200 = 12 mL/h

Answer

R = 12 mL/h
7.IV fluids & fluid balance

Answer: B = 740 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 240 + 100 = 340 mL
IV infusion: 125·8 = 1000 mL
IV antibiotic: 2·100 = 200 mL
total intake = 1540 mL

Total output

200 + 500 + 100 = 800 mL

Balance

B = 1540 − 800 = 740 mL

Answer

B = 740 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 2.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 200 = 300 mL

Time

t = 300/120 = 2.5 h

Answer

t = 2.5 h

That is about 2 h 30 min, so the bag runs out at about 10:00.

9.Nursing math & unit conversions

Answer: h = 191 cm

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Height in inches

6·12 + 3 = 75 in

Inches to centimetres

h = 75·2.54 = 190.5 ≈ 191 cm

Answer

h = 191 cm
10.Nursing math & unit conversions

Answer: V = 775 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

½ tsp = 0.5·5 = 2.5 mL
½ tbsp = 0.5·15 = 7.5 mL
3 cups = 3·240 = 720 mL
1½ fl oz = 1.5·30 = 45 mL

Add

V = 2.5 + 7.5 + 720 + 45 = 775 mL

Answer

V = 775 mL

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