NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
30 kg7.5 mg/kg/day2× per dayD = ? mg

A patient weighs 30 kg. The prescribed dose is 7.5 mg/kg per day, given in 2 equal doses. How many milligrams D are given per dose?

30 kg7.5 mg/kg/day2× per day
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 440 micrograms. The ampoule contains 4 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

440 mcg4 mg/mL
V = mL
3.IV infusion ratesMedium
500 mL60 gtt/mL6 h? gtt/min

Infuse 500 mL over 6 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL6 h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
200 mg250 mL8 mL/h? mg/h

A bag contains 200 mg of a drug in 250 mL and runs at 8 mL/h. How many milligrams per hour D does the patient receive?

200 mg/250 mL8 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
25 000 units500 mLheparin? mL/h103 kg18 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 500 mL. The order is 18 units/kg/h for a patient who weighs 103 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/500 mL18 units/kg/h103 kg
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h55 kg2.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 2.5 mcg/kg/min for a patient who weighs 55 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL2.5 mcg/kg/min55 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftsoup250 mLtea150 mLwater240 mLice chips100 mLIV infusion50 mL/h × 8 hIV antibiotic1 × 100 mLurine300 mLurine325 mLurine150 mLwound drain80 mLvomit150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

soup: 250 mLtea: 150 mLwater: 240 mLice chips: 100 mLIV infusion: 50 mL/h × 8 hIV antibiotic: 1 × 100 mLurine: 300 mLurine: 325 mLurine: 150 mLwound drain: 80 mLvomit: 150 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL→ 100 mL/hstart 18:00ttotal​ = ? h125 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 18:00 at 125 mL/h. After 4 hours the rate is changed to 100 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL125 mL/h · 4 h100 mL/h
t = h
9.Nursing math & unit conversionsMedium
8 lb 11 oz? kg1 lb = 16 oz1 kg = 2.2 lb

Practice exercise (made-up values, not clinical guidance). A newborn weighs 8 lb 11 oz. Using 1 lb = 16 oz and 1 kg = 2.2 lb, find the weight m in kilograms. Round to two decimal places.

8 lb 11 oz1 lb = 16 oz1 kg = 2.2 lb
m = kg
10.Nursing math & unit conversionsHard
1 mcg/kg/min? mg/h56 kg1 h = 60 min1 mg = 1000 mcg

Practice exercise (made-up values, not clinical guidance). An order reads 1 mcg/kg/min for a patient who weighs 56 kg. Express the dose rate D in mg/h. Round to two decimal places.

1 mcg/kg/min56 kg
D = mg/h

3Solutions

1.Dosage calculations

Answer: D = 112.5 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

7.5·30 = 225 mg

Per dose

D = 225/2 = 112.5 mg

Answer

D = 112.5 mg
2.Dosage calculations

Answer: V = 0.11 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

4 mg/mL = 4000 mcg/mL

Volume

V = 440/4000 = 0.11 mL

Answer

V = 0.11 mL
3.IV infusion rates

Answer: R = 83 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

6·60 = 360 min

Drip rate

R = 500·60/360 = 83.33 ≈ 83 gtt/min

Answer

R = 83 gtt/min

At the bedside you round to the nearest whole drop: 83 gtt/min.

4.IV infusion rates

Answer: D = 6.4 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

200/250 = 0.8 mg/mL

Dose rate

D = 0.8·8 = 6.4 mg/h

Answer

D = 6.4 mg/h
5.Pediatric & critical-care dosing

Answer: R = 37.1 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

18·103 = 1 854 units/h

Concentration

25 000/500 = 50 units/mL

Pump rate

R = 1854/50 = 37.08 ≈ 37.1 mL/h

Answer

R = 37.1 mL/h
6.Pediatric & critical-care dosing

Answer: R = 8.3 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

2.5·55 = 137.5 mcg/min
137.5·60 = 8250 mcg/h

Pump rate

R = 8250/1000 = 8.25 ≈ 8.3 mL/h

Answer

R = 8.3 mL/h
7.IV fluids & fluid balance

Answer: B = 185 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 250 + 150 + 240 = 640 mL
ice chips: 100/2 = 50 mL
IV infusion: 50·8 = 400 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1190 mL

Total output

300 + 325 + 150 + 80 + 150 = 1005 mL

Balance

B = 1190 − 1005 = 185 mL

Answer

B = 185 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 9 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

125·4 = 500 mL
1000 − 500 = 500 mL left

Second part

500/100 = 5 h

Total time

t = 4 + 5 = 9 h

Answer

t = 9 h

That is about 9 h 00 min, so the bag runs out at about 03:00.

9.Nursing math & unit conversions

Answer: m = 3.95 kg

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Ounces to pounds

11 oz/16 = 0.6875 lb
8 + 0.6875 = 8.688 lb

Pounds to kilograms

m = 8.688/2.2 = 3.949 ≈ 3.95 kg

Answer

m = 3.95 kg
10.Nursing math & unit conversions

Answer: D = 3.36 mg/h

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 1 mcg/kg/min × 56 kg × (60 min/1 h) × (1 mg/1000 mcg)

Calculate

D = 1·56·60/1000 = 3.36 mg/h

Answer

D = 3.36 mg/h

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