NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 16 kg is prescribed 5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

16 kg5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 2000 units of a drug that comes as 5000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

2000 units5000 units/mL
V = mL
3.IV infusion ratesMedium
V = ?15 gtt/mL40 gtt/min8 h

A drip runs at 40 gtt/min through a set of 15 gtt/mL. How many millilitres V does the patient receive in 8 hours?

40 gtt/min15 gtt/mL8 h
V = mL
4.IV infusion ratesHard
2 g250 mL? mL/h3 mg/min

A bag contains 2 g of a drug in 250 mL. The order is 3 mg per minute. At what rate R do you set the pump, in mL/h?

2 g/250 mL3 mg/min
R = mL/h
5.Pediatric & critical-care dosingMedium
25 000 units500 mLheparin? mL/h59 kg18 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 500 mL. The order is 18 units/kg/h for a patient who weighs 59 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/500 mL18 units/kg/h59 kg
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h58 kg7.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 7.5 mcg/kg/min for a patient who weighs 58 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL7.5 mcg/kg/min58 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjelly100 mLmilk200 mLIV infusion50 mL/h × 12 hIV antibiotic2 × 50 mLurine500 mLurine175 mLwound drain130 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

jelly: 100 mLmilk: 200 mLIV infusion: 50 mL/h × 12 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL→ 80 mL/hstart 10:00ttotal​ = ? h75 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 10:00 at 75 mL/h. After 4 hours the rate is changed to 80 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL75 mL/h · 4 h80 mL/h
t = h
9.Nursing math & unit conversionsMedium
5.7726 mL? mLround to 0.1 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for an injection gives 5.7726 mL. The rule in this exercise is that volumes of 1 mL or more are rounded to the nearest tenth of a mL. What value x do you record?

5.7726 mL
x = mL
10.Nursing math & unit conversionsHard
½ tbsp? mL2 cups? mL1 tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes ½ tbsp of liquid supplement, 2 cups of tea, 1 tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 3.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·16 = 80 mg

Volume

V = 80/25 = 3.2 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 3.2 mL
2.Dosage calculations

Answer: V = 0.4 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 2000/5000 = 0.4 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.4 mL
3.IV infusion rates

Answer: V = 1280 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/15 = 160 mL/h

Volume

V = 160·8 = 1280 mL

Answer

V = 1280 mL
4.IV infusion rates

Answer: R = 22.5 mL/h

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

2000 mg/250 mL = 8 mg/mL

Dose per hour

3·60 = 180 mg/h

Pump rate

R = 180/8 = 22.5 mL/h

Answer

R = 22.5 mL/h
5.Pediatric & critical-care dosing

Answer: R = 21.2 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

18·59 = 1 062 units/h

Concentration

25 000/500 = 50 units/mL

Pump rate

R = 1062/50 = 21.24 ≈ 21.2 mL/h

Answer

R = 21.2 mL/h
6.Pediatric & critical-care dosing

Answer: R = 26.1 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

7.5·58 = 435 mcg/min
435·60 = 26100 mcg/h

Pump rate

R = 26100/1000 = 26.1 mL/h

Answer

R = 26.1 mL/h
7.IV fluids & fluid balance

Answer: I = 1000 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 100 + 200 = 300 mL
IV infusion: 50·12 = 600 mL
IV antibiotic: 2·50 = 100 mL
I = 1000 mL

Answer

I = 1000 mL
8.IV fluids & fluid balance

Answer: t = 12.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·4 = 300 mL
1000 − 300 = 700 mL left

Second part

700/80 = 8.75 h

Total time

t = 4 + 8.75 = 12.75 ≈ 12.8 h

Answer

t = 12.8 h

That is about 12 h 45 min, so the bag runs out at about 22:45.

9.Nursing math & unit conversions

Answer: x = 5.8 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

5.7726 → 7

Only the next digit decides

5.7726 → 7
7 is 5 or more, so round 7 up.
The digits after it (26) are ignored: round once, never step by step.

Round

x = 5.8 mL

Answer

x = 5.8 mL
10.Nursing math & unit conversions

Answer: V = 492.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

½ tbsp = 0.5·15 = 7.5 mL
2 cups = 2·240 = 480 mL
1 tsp = 1·5 = 5 mL

Add

V = 7.5 + 480 + 5 = 492.5 mL

Answer

V = 492.5 mL

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