Respiratory Care and Oxygen Therapy: cram pack

Formula sheets, the key method steps for every topic and 8 practice problems, with full solutions at the back.

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1Formulas and methods

Oxygen therapy & respiratory calculations

Nasal cannula
FiO₂ ≈ 21% + 4% × L/min (1–6 L/min)
Cylinder duration
min = (psi − 200) × factor / (L/min); D 0.16, E 0.28, H 3.14 L/psi
Minute and alveolar ventilation
V̇E = VT·f, V̇A = (VT − VD)·f
Predicted body weight
men 50 + 0.91 × (cm − 152.4); women 45.5 + 0.91 × (cm − 152.4)
P/F ratio (Berlin, PEEP ≥ 5)
mild > 200–300, moderate > 100–200, severe ≤ 100 mmHg
Oxygen content
CaO₂ = 1.34·Hb·SaO₂ + 0.003·PaO₂
Oxygen delivery
DO₂ = CaO₂ × CO × 10
ROX index
(SpO₂/FiO₂)/RR

Method

  1. Put every value in the units of the formula: FiO₂ and SaO₂ as fractions, PaO₂ in mmHg, Hb in g/dL.
  2. For a cylinder, subtract the safe residual, multiply by the cylinder factor and divide by the flow.
  3. Round cylinder times and flows down, never up.
  4. For the P/F ratio, check the PEEP first, then divide PaO₂ by FiO₂ and compare with 300, 200 and 100 mmHg.
  5. For ventilation, subtract the dead space for alveolar ventilation and use the predicted body weight for tidal volumes.

Arterial blood gas interpretation

Normal ranges
pH 7.35–7.45, PaCO₂ 35–45 mmHg (4.7–6.0 kPa), HCO₃⁻ 22–26 mmol/L
ROME
Respiratory: PaCO₂ opposite to pH; Metabolic: HCO₃⁻ equal to pH
Winter’s formula
PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2
Metabolic alkalosis
PaCO₂ ≈ 0.7·HCO₃⁻ + 21
Anion gap
AG = Na⁺ − (Cl⁻ + HCO₃⁻) ≈ 8–12
Albumin-corrected gap
AG + 2.5·(4.0 − alb g/dL) = AG + 0.25·(40 − alb g/L)
Delta ratio
(AG − 12)/(24 − HCO₃⁻)
P/F ratio
PaO₂/FiO₂
Alveolar gas equation
PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8
Serum osmolality
2·Na⁺ + glucose + urea (2·Na⁺ + glucose/18 + BUN/2.8)

Method

  1. Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
  2. Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
  3. Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
  4. In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
  5. Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.

Clinical assessment scores

Glasgow Coma Scale
GCS = E (1–4) + V (1–5) + M (1–6) = 3–15
APGAR
5 signs × 0–2 = 0–10; 7–10 reassuring, 4–6 moderately abnormal, 0–3 low
Braden scale
5 × (1–4) + 1 × (1–3) = 6–23; ≤ 18 at risk
Morse fall scale
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²

Method

  1. Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
  2. Score every item separately, matching the description to its level.
  3. Add the item scores and check that the total lies inside the range.
  4. Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
  5. For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².

Med-surg: cardiovascular & respiratory

Method

  1. Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
  2. Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
  3. Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
  4. Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
  5. Choose the safe first action, then escalate and reassess.

2Practice problems

1.Oxygen therapy & respiratory calculationsMedium
600psiEf = 0.28 L/psi5 L/minresidual 200 psit = ? min

Practice exercise (made-up values, not clinical guidance). A size E oxygen cylinder (factor 0.28 L/psi) reads 600 psi and runs at 5 L/min. Keeping a safe residual of 200 psi, how many minutes t will it last? Round down to a whole minute.

600 psif = 0.28 L/psi5 L/min200 psi
t = min
2.Oxygen therapy & respiratory calculationsHard
1350psiEf = 0.28 L/psi30 minresidual 200 psiQ = ? L/min

Practice exercise (made-up values, not clinical guidance). A transfer will take 30 minutes. The size E cylinder (factor 0.28 L/psi) reads 1350 psi. Keeping a safe residual of 200 psi, what is the highest whole-number flow Q in L/min that lasts the whole transfer?

30 min1350 psif = 0.28 L/psi200 psi
Q = L/min
3.Arterial blood gas interpretationMedium

A practice gas shows a metabolic acidosis with HCO₃⁻ 12 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.

HCO₃⁻ 12 mmol/L
PaCO₂ = mmHg
4.Arterial blood gas interpretationHard
pH7.357.457.32PaCO₂mmHg354532HCO₃⁻mmol/L222616appropriate compensationadded respiratory acidosisadded respiratory alkalosis

A practice gas shows a metabolic acidosis: pH 7.32, PaCO₂ 32 mmHg (4.3 kPa), HCO₃⁻ 16 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.

pH 7.32PaCO₂ 32 mmHg (4.3 kPa)HCO₃⁻ 16 mmol/L
  1. 1appropriate compensation
  2. 2added respiratory acidosis
  3. 3added respiratory alkalosis
5.Clinical assessment scoresMedium
E1 / 4+V2 / 5+M? / 6GCS 4?

Practice exercise (made-up values, not clinical guidance). A practice chart records GCS 4, with E1 and V2. What motor score M was recorded, and which response does it describe? Give the number.

GCS 4E1V2
M =
6.Clinical assessment scoresHard
underweighthealthy weightoverweightobesity class Iobesity class IIobesity class III

Practice exercise (made-up values, not clinical guidance). An adult weighs 78 kg and is 191 cm tall. Calculate the BMI and click the WHO weight category.

78 kg191 cm
  1. 1underweight
  2. 2healthy weight
  3. 3overweight
  4. 4obesity class I
  5. 5obesity class II
  6. 6obesity class III
7.Med-surg: cardiovascular & respiratoryMedium

A patient choosing between a mechanical and a biological heart valve asks about the main difference. Which answer is accurate?

  1. ABoth types need no medicines after surgery
  2. BBiological valves last longer but need lifelong warfarin
  3. CMechanical valves wear out within one year
  4. DMechanical valves last longer but need lifelong anticoagulation
8.Med-surg: cardiovascular & respiratoryHard

A patient with asthma needs their reliever every three hours and their peak flow is falling well below their personal best. What does their action plan most likely advise?

  1. ADo extra exercise to open the airways
  2. BStop the preventer inhaler for a few days to rest the lungs
  3. CFollow the worsening-asthma steps and get a same-day review
  4. DWait two weeks to see whether it improves without any change

3Solutions

1.Oxygen therapy & respiratory calculations

Answer: t = 22 min

Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).

Usable litres

(600 − 200)·0.28 = 112 L

Duration

112/5 = 22.4 min → t = 22 min

Answer

t = 22 min
2.Oxygen therapy & respiratory calculations

Answer: Q = 10 L/min

Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).

Usable litres

(1350 − 200)·0.28 = 322 L

Highest flow

322/30 = 10.73 L/min → Q = 10 L/min

Answer

Q = 10 L/min
3.Arterial blood gas interpretation

Answer: PaCO₂ = 26 mmHg

Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.

Winter’s formula

PaCO₂ = 1.5·12 + 8 = 26 mmHg
range: 24–28 mmHg

Answer

PaCO₂ = 26 mmHg
4.Arterial blood gas interpretation

Answer: appropriate compensation

Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.

Expected PaCO₂

1.5·16 + 8 = 32 → 30–34 mmHg

Compare

measured: 32 mmHg → appropriate compensation

Answer

appropriate compensation
5.Clinical assessment scores

Answer: M = 1

Glasgow Coma Scale: add the best response in three areas. Eye opening E: 4 spontaneous, 3 to sound or speech, 2 to pressure, 1 none. Verbal V: 5 oriented, 4 confused, 3 inappropriate words, 2 incomprehensible sounds, 1 none. Motor M: 6 obeys commands, 5 localises, 4 normal flexion (withdraws), 3 abnormal flexion, 2 extension, 1 none. The total runs from 3 to 15. After a head injury, 13–15 is usually called mild, 9–12 moderate and 3–8 severe.

Motor score

M = 4 − 1 − 2 = 1
M1: no movement at all

Answer

M = 1
6.Clinical assessment scores

Answer: healthy weight

Body mass index: BMI = weight (kg)/height (m)², with the height converted to metres first. With pounds and inches, BMI = 703 × weight (lb)/height (in)². WHO adult categories: below 18.5 underweight, 18.5–24.9 healthy weight, 25.0–29.9 overweight, 30.0–34.9 obesity class I, 35.0–39.9 obesity class II and 40 or more obesity class III.

BMI

BMI = 78/1.91² = 21.38

Category

healthy weight

Answer

healthy weight
7.Med-surg: cardiovascular & respiratory

Answer: D · Mechanical valves last longer but need lifelong anticoagulation

Why this is the answer

Mechanical valves are very durable but are thrombogenic, so lifelong warfarin is needed. Biological (tissue) valves usually do not need long-term anticoagulation but wear out over time and may need replacement. Age, lifestyle and bleeding risk guide the choice.

Answer

D · Mechanical valves last longer but need lifelong anticoagulation
8.Med-surg: cardiovascular & respiratory

Answer: C · Follow the worsening-asthma steps and get a same-day review

Why this is the answer

Personal asthma action plans set steps based on symptoms and peak flow compared with the personal best. Increasing reliever need and a falling peak flow mean worsening asthma: treatment is increased as the plan says (sometimes with oral steroids) and urgent review is sought. Severe signs need emergency care.

Answer

C · Follow the worsening-asthma steps and get a same-day review

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