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Nama: ____________________ Tanggal: ____________
1.Mudah
Baclofen is used mainly to treat:
AMuscle spasticity, for example in multiple sclerosis
BBacterial infections of the skin
CAcid reflux and heartburn
DHigh blood pressure in pregnancy and pre-eclampsia
2.Mudah
Obat mana yang membalikkan efek heparin?
AProtamin sulfat
BFlumazenil
CVitamin K
DNalokson
3.Mudah
Which harmless effect of rifampicin should patients be warned about?
ABlue colouring of the fingernails and lips
BOrange-red colouring of urine, sweat and tears
CWhite spots on the teeth
DGreen colouring of the stools
4.Sedang
Long-term use of metformin can cause a deficiency of which vitamin?
AVitamin A
BVitamin D
CVitamin B12
DVitamin K
5.Sedang
After naloxone reverses an opioid overdose, why must the patient be watched closely?
ANaloxone may wear off before the opioid does, so breathing can slow again
BNaloxone itself causes respiratory depression at high doses
CNaloxone often causes severe low blood glucose a few hours after the dose
DNaloxone makes the opioid stay longer in the body
6.Sedang
Why is hypovolaemia corrected with IV fluids before or while starting a vasopressor?
AVasopressors only work when they are diluted in large fluid volumes
BFluids stop the vasopressor causing a fever
CVasopressors cause the patient to retain too much fluid
DVasopressors cannot keep perfusion up if the circulation is under-filled
7.Sulit
Obat X memberikan respons maksimum 100% dengan EC50 1 mg. Obat Y memberikan respons maksimum 100% dengan EC50 10 mg. Pernyataan mana yang benar?
AY lebih poten daripada X, dan keduanya memiliki efikasi yang sama
BX lebih poten daripada Y, dan keduanya memiliki efikasi yang sama
CX memiliki efikasi lebih tinggi daripada Y
DY memiliki efikasi lebih tinggi daripada X
8.Sulit
Why is clavulanic acid combined with amoxicillin (co-amoxiclav)?
AIt slows the kidney excretion of amoxicillin
BIt reduces the risk of penicillin allergy
CIt inhibits beta-lactamase enzymes that would destroy amoxicillin
DIt makes amoxicillin cross the blood–brain barrier more easily
Kunci jawaban
1. A · Muscle spasticity, for example in multiple sclerosis
2. A · Protamin sulfat
3. B · Orange-red colouring of urine, sweat and tears
4. C · Vitamin B12
5. A · Naloxone may wear off before the opioid does, so breathing can slow again
6. D · Vasopressors cannot keep perfusion up if the circulation is under-filled
7. B · X lebih poten daripada Y, dan keduanya memiliki efikasi yang sama
8. C · It inhibits beta-lactamase enzymes that would destroy amoxicillin
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