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Nama: ____________________ Tanggal: ____________
1.Mudah
Stimulation of which receptor increases heart rate and the force of contraction?
AAlpha-2 adrenergic receptor
BBeta-2 adrenergic receptor
CMuscarinic M2 receptor
DBeta-1 adrenergic receptor
2.Mudah
Statin seperti atorvastatin menurunkan kolesterol dengan menghambat enzim apa?
ALipoprotein lipase
BHMG-CoA reduktase
CEnzim pengubah angiotensin
DSiklooksigenase
3.Mudah
Why is HIV treated with a combination of antiretroviral drugs?
ABecause each single drug cures only part of the infection
BTo make the treatment shorter, usually a few weeks
CBecause one drug alone causes no side effects
DTo suppress the virus and prevent drug resistance
4.Sedang
Faktor mana yang meningkatkan risiko toksisitas litium?
AMinum air lebih banyak
BDehidrasi
CMengonsumsi dosis bersama makanan
DDiet tinggi garam
5.Sedang
When does oseltamivir give the most benefit in influenza?
AOnly after a bacterial pneumonia has developed
BOnly after symptoms have lasted at least one week
CWhen started within 48 hours of the first symptoms
DAt any time, as the timing makes no difference
6.Sedang
Which teaching about antiepileptic drugs is most important?
ATake a double dose if you feel a seizure coming
BAlcohol has no effect on seizure control
CStop the drug when you have had no seizures for one whole week
DDo not stop the drug suddenly, as this can trigger severe seizures
7.Sulit
Klirens suatu obat turun menjadi separuh akibat gagal ginjal, sementara volume distribusinya tetap. Apa yang terjadi pada waktu paruhnya?
ABerkurang separuh
BNaik empat kali lipat
CTetap sama
DBerlipat dua
8.Sulit
A patient taking metoprolol is also started on verapamil. Which adverse effect is most likely?
ARebound tachycardia and hypertension
BHypoglycaemia and weight gain
CHyperkalaemia and muscle weakness
DSevere bradycardia and heart block
Kunci jawaban
1. D · Beta-1 adrenergic receptor
2. B · HMG-CoA reduktase
3. D · To suppress the virus and prevent drug resistance
4. B · Dehidrasi
5. C · When started within 48 hours of the first symptoms
6. D · Do not stop the drug suddenly, as this can trigger severe seizures
7. D · Berlipat dua
8. D · Severe bradycardia and heart block
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