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Nama: ____________________ Tanggal: ____________
1.Mudah
Nitrofurantoin is used mainly to treat:
ABacterial meningitis in adults and children
BUncomplicated cystitis (lower urinary infection)
CPneumonia
DBone infections
2.Mudah
Disulfiram is used in alcohol use disorder because it:
ACures liver damage caused by alcohol
BCauses an unpleasant reaction if alcohol is drunk
CRemoves alcohol from the blood faster
DReplaces alcohol at its receptors in the brain
3.Mudah
Apa itu indeks terapeutik?
ARasio antara dosis toksik dan dosis efektif
BPersentase dosis oral yang mencapai sirkulasi sistemik
CWaktu untuk mencapai keadaan tunak
DJumlah dosis per hari
4.Sedang
An adult patient is due to receive digoxin. The apical pulse, counted for a full minute, is 52 beats per minute. What should the nurse do?
AGive the dose with food to slow absorption
BWithhold the dose and notify the prescriber
CGive half the dose and document the pulse
DGive the dose and recheck the pulse in one hour
5.Sedang
Fraksi obat mana di dalam plasma yang dapat mencapai reseptor dan menghasilkan efek?
AFraksi tidak terikat (bebas)
BFraksi yang tersimpan di sel darah merah
CFraksi yang terikat globulin
DFraksi yang terikat albumin
6.Sedang
Which statement about allopurinol is correct?
AIt is taken only during an acute attack and stopped as soon as the pain settles
BIt increases uric acid production to flush out crystals
CIt works within an hour to relieve joint pain
DIt lowers uric acid over time and does not relieve the pain of an acute attack
7.Sulit
Why is vancomycin given by mouth, not intravenously, for Clostridioides difficile infection?
AOral vancomycin is absorbed into the blood better than IV vancomycin
BThe oral form is cheaper but has the same effect as IV
CIntravenous vancomycin causes C. difficile infection
DOral vancomycin is not absorbed, so it reaches high levels in the colon
8.Sulit
A woman with chronic hypertension who takes lisinopril is now pregnant. What is the key concern?
ALisinopril works better in pregnancy, so the dose should be increased
BLisinopril has no known fetal effects and should be continued
CAll antihypertensives must be stopped in pregnancy
DACE inhibitors harm fetal kidneys, so a safer drug is used
Kunci jawaban
1. B · Uncomplicated cystitis (lower urinary infection)
2. B · Causes an unpleasant reaction if alcohol is drunk
3. A · Rasio antara dosis toksik dan dosis efektif
4. B · Withhold the dose and notify the prescriber
5. A · Fraksi tidak terikat (bebas)
6. D · It lowers uric acid over time and does not relieve the pain of an acute attack
7. D · Oral vancomycin is not absorbed, so it reaches high levels in the colon
8. D · ACE inhibitors harm fetal kidneys, so a safer drug is used
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