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Nama: ____________________ Tanggal: ____________
1.Mudah
Infliximab and adalimumab are biological drugs that block:
AVitamin K recycling
BTumour necrosis factor-alpha (TNF-alpha)
CHistamine H1 receptors in the skin and airways
DInsulin receptors
2.Mudah
Which drug class is first-line for stopping a seizure in status epilepticus?
AOpioids, such as IV morphine
BAntihistamines, such as IV chlorphenamine
CBeta blockers, such as IV metoprolol
DBenzodiazepines, such as IV lorazepam
3.Mudah
Donepezil, used in Alzheimer's disease, belongs to which class?
ASelective serotonin reuptake inhibitors
BAcetylcholinesterase inhibitors
CBenzodiazepines
DDopamine agonists
4.Sedang
Methylergometrine (methylergonovine) is prescribed for postpartum bleeding. Which finding would make the nurse withhold it and check with the prescriber?
AHaemoglobin slightly below normal
BTemperature of 37,2 °C (99 °F)
CBlood pressure of 160/105 mmHg
DHeart rate of 88 per minute
5.Sedang
Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?
AIntravenous infusion over 30 minutes
BDeep intramuscular only
CIntravenous push
DSubcutaneous in the abdomen
6.Sedang
A patient is starting olanzapine. Which monitoring is most important over the following months?
APeak expiratory flow
BWeight, blood glucose and blood lipids
CHearing tests and vision tests every month
DINR and platelet count
7.Sulit
A patient on simvastatin is prescribed gemfibrozil. What is the main concern?
AA sharp rise in LDL cholesterol and triglycerides
BSevere hypoglycaemia
CLoss of all lipid-lowering effect
DA much higher risk of myopathy and rhabdomyolysis
8.Sulit
A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?
ABone marrow suppression, because both drugs inhibit folate metabolism
BSevere hypertension from the combination
CHypoglycaemia from reduced liver glucose output
DLoss of antibiotic effect because methotrexate binds trimethoprim
Kunci jawaban
1. B · Tumour necrosis factor-alpha (TNF-alpha)
2. D · Benzodiazepines, such as IV lorazepam
3. B · Acetylcholinesterase inhibitors
4. C · Blood pressure of 160/105 mmHg
5. B · Deep intramuscular only
6. B · Weight, blood glucose and blood lipids
7. D · A much higher risk of myopathy and rhabdomyolysis
8. A · Bone marrow suppression, because both drugs inhibit folate metabolism
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