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Nama: ____________________ Tanggal: ____________
1.Mudah
A patient taking furosemide is advised to eat potassium-rich foods. Which food is a good choice?
AEgg whites
BBananas
CWhite rice
DButter
2.Mudah
What is the most common side effect of first-generation antihistamines such as diphenhydramine?
ADrowsiness
BRaised blood pressure
CDiarrhoea
DInsomnia
3.Mudah
Why do nurses wear chemotherapy-tested gloves and gowns when handling cytotoxic drugs?
ATo protect the drug from light
BBecause cytotoxic drugs are radioactive and give off radiation
CTo keep the drugs warm during the infusion
DTo avoid exposure to drugs that may cause cancer or birth defects
4.Sedang
Why is directly observed therapy (DOT) often used for tuberculosis?
AThe drugs work only if a nurse is present
BPatients with TB cannot swallow tablets
CTreatment lasts months, and missed doses cause resistance
DTB drugs must always be given intravenously in hospital
5.Sedang
Berapa lama kira-kira obat yang diberikan dengan interval teratur mencapai keadaan tunak?
A1 waktu paruh
B10 waktu paruh
C4 sampai 5 waktu paruh
DHanya bergantung pada besarnya dosis
6.Sedang
A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?
AStop the hydrocortisone until the fever settles, to let the body recover
BHalve the hydrocortisone to reduce side effects
CMake no change, as illness does not affect cortisol needs
DIncrease the dose as instructed (sick-day rules) and seek help if vomiting
7.Sulit
Sifat apa yang membuat obat lebih mungkin menembus sawar darah-otak?
ABerat molekul besar dan ikatan protein kuat
BKelarutan air tinggi dan ionisasi kuat
CKelarutan lemak tinggi dan ukuran kecil
DMuatan positif pada pH fisiologis
8.Sulit
A patient with severe liver cirrhosis needs a benzodiazepine for alcohol withdrawal. Why is lorazepam often chosen instead of diazepam?
ALorazepam is cleared by simple conjugation and has no active metabolites
BLorazepam does not cause sedation in liver disease
CLorazepam is a stronger anticonvulsant than all other benzodiazepines
DLorazepam is excreted unchanged in the urine without any metabolism
Kunci jawaban
1. B · Bananas
2. A · Drowsiness
3. D · To avoid exposure to drugs that may cause cancer or birth defects
4. C · Treatment lasts months, and missed doses cause resistance
5. C · 4 sampai 5 waktu paruh
6. D · Increase the dose as instructed (sick-day rules) and seek help if vomiting
7. C · Kelarutan lemak tinggi dan ukuran kecil
8. A · Lorazepam is cleared by simple conjugation and has no active metabolites
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