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Nama: ____________________ Tanggal: ____________
1.Mudah
Which intramuscular site is recommended for infants?
ADorsogluteal (upper outer buttock)
BDeltoid
CVentral forearm
DVastus lateralis (outer thigh)
2.Mudah
Why is adrenaline (epinephrine) sometimes added to a local anaesthetic injection?
AIt speeds up the removal of the anaesthetic from the tissue into the blood
BIt makes the anaesthetic act on the brain as well
CIt prevents allergic reactions to the anaesthetic
DIt constricts vessels, so the block lasts longer and less enters the blood
3.Mudah
Which vitamin reverses the effect of warfarin?
AVitamin K
BVitamin E
CVitamin B12
DVitamin C
4.Sedang
A patient taking levodopa finds that the drug works poorly after large meals. Which advice is most appropriate?
ATake every dose with a large glass of milk and a protein snack
BAvoid taking doses at the same time as high-protein meals
CDouble the dose after each meal
DTake the drug only at bedtime
5.Sedang
Reseptor apa yang terutama disekat oleh penyekat beta seperti metoprolol?
AReseptor adrenergik beta-1 di jantung
BReseptor alfa-1 di pembuluh darah
CReseptor muskarinik di jantung
DReseptor beta-3 di jaringan lemak
6.Sedang
Which drug is used for torsades de pointes?
AIntravenous magnesium sulfate
BIntravenous adenosine (rapid push)
CIntravenous verapamil
DOral digoxin
7.Sulit
A patient who used cocaine has chest pain, agitation, a high temperature, sweating, tachycardia and dilated pupils. Which drug class is commonly first-line for the agitation and sympathetic overactivity?
AAntihistamines
BAnticholinergic drugs
CBenzodiazepines
DOpioid antagonists
8.Sulit
Bayi baru lahir yang diberi kloramfenikol dapat mengalami "grey baby syndrome". Apa alasan utamanya?
ABayi baru lahir membentuk antibodi terhadap obat
BKloramfenikol diubah menjadi vitamin K pada neonatus
CGinjal bayi baru lahir mengekskresikan obat terlalu cepat, sehingga diberikan dosis lebih tinggi
DGlukuronidasi di hati yang belum matang membuat obat terakumulasi
Kunci jawaban
1. D · Vastus lateralis (outer thigh)
2. D · It constricts vessels, so the block lasts longer and less enters the blood
3. A · Vitamin K
4. B · Avoid taking doses at the same time as high-protein meals
5. A · Reseptor adrenergik beta-1 di jantung
6. A · Intravenous magnesium sulfate
7. C · Benzodiazepines
8. D · Glukuronidasi di hati yang belum matang membuat obat terakumulasi
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