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Nama: ____________________ Tanggal: ____________
1.Mudah
What is a prodrug?
AA drug that is inactive until the body converts it into its active form
BA drug that prevents or reverses the effect of another drug in the body
CA drug that has passed all clinical trials
DA drug that is given before surgery
2.Mudah
How is pernicious anaemia usually treated?
AWith vitamin B12 injections, usually for life
BWith oral iron tablets for three months, then stopping
CWith folic acid alone
DWith blood transfusions every month
3.Mudah
Apa yang dijelaskan oleh "bioavailabilitas"?
ASeberapa kuat obat berikatan dengan reseptornya
BBagian dosis yang terikat pada protein plasma dalam sirkulasi
CSeberapa cepat obat diekskresikan
DBagian dosis yang mencapai sirkulasi sistemik tanpa berubah
4.Sedang
Which advice helps reduce the most common side effect of varenicline?
ATake double doses in the first week
BTake it with alcohol to reduce nausea
CTake it after food with a full glass of water
DTake it on an empty stomach at bedtime with a little milk
5.Sedang
Efek samping mana yang khas untuk penyekat kanal kalsium amlodipin?
ABatuk kering
BBronkospasme
CPembengkakan pergelangan kaki
DHiperkalemia
6.Sedang
Why is a progestogen added to oestrogen in hormone replacement therapy for a woman who still has her uterus?
ATo lower the risk of blood clots to zero
BTo protect against endometrial hyperplasia and cancer
CTo prevent breast cancer completely
DTo reduce hot flushes much more than oestrogen alone can
7.Sulit
Golongan obat apa yang dapat menyebabkan hiperkalemia yang mengancam jiwa bila digabung dengan penghambat ACE?
ADiuretik tiazid
BDiuretik loop seperti furosemid intravena dosis tinggi
CDiuretik hemat kalium seperti spironolakton
DPenghambat pompa proton
8.Sulit
A postoperative patient using morphine PCA is very drowsy, hard to rouse and has a respiratory rate of 7 per minute. What should the nurse do first?
AReduce the PCA dose and leave the pump running
BStop the PCA, try to rouse the patient and give naloxone as per protocol
CLet the patient sleep and recheck in one hour
DEncourage the patient to press the button only when awake and in pain
Kunci jawaban
1. A · A drug that is inactive until the body converts it into its active form
2. A · With vitamin B12 injections, usually for life
3. D · Bagian dosis yang mencapai sirkulasi sistemik tanpa berubah
4. C · Take it after food with a full glass of water
5. C · Pembengkakan pergelangan kaki
6. B · To protect against endometrial hyperplasia and cancer
7. C · Diuretik hemat kalium seperti spironolakton
8. B · Stop the PCA, try to rouse the patient and give naloxone as per protocol
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