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Nama: ____________________ Tanggal: ____________
1.Mudah
Finasteride is used in benign prostatic hyperplasia because it:
AKills bacteria in the prostate
BIncreases testosterone production
CRelaxes smooth muscle in the prostate within hours of the first dose
DInhibits 5-alpha reductase and slowly shrinks the prostate
2.Mudah
Which of these is a second-generation (atypical) antipsychotic?
AOlanzapine
BFluphenazine
CHaloperidol
DChlorpromazine
3.Mudah
Clomifene is used mainly to:
ATreat menopausal hot flushes and night sweats
BStop postpartum bleeding
CPrevent pregnancy
DInduce ovulation in women with infertility
4.Sedang
Mengapa kortikosteroid oral jangka panjang tidak boleh dihentikan mendadak?
ASistem imun akan langsung menyerang hati dan kelenjar adrenal
BObat membentuk metabolit toksik ketika dihentikan
CPenghentian menyebabkan kenaikan glukosa darah mendadak
DKelenjar adrenal tertekan dan mungkin tidak membuat cukup kortisol
5.Sedang
Which rule applies to intravenous potassium chloride?
AIt must be diluted and given as an infusion, never as an IV push
BIt may be given intramuscularly if there is no IV access
CIt is mixed into blood products to save time
DIt is given as a rapid IV push to correct low levels quickly
6.Sedang
How is adenosine given for supraventricular tachycardia?
AAs a slow infusion over one hour
BAs an intramuscular injection into the outer thigh muscle
CAs a tablet under the tongue
DAs a rapid IV push followed by a fast saline flush
7.Sulit
Untuk obat dengan eliminasi orde pertama, menggandakan dosis (tanpa mengubah interval) akan:
AMenggandakan waktu paruh
BTidak mengubah kadar keadaan tunak tetapi menjadikan waktu untuk mencapainya separuhnya
CMemangkas setengah waktu untuk mencapai keadaan tunak
DMenggandakan kadar keadaan tunak tetapi tidak mengubah waktu untuk mencapainya
8.Sulit
A patient with asthma starts timolol eye drops for glaucoma and soon becomes wheezy. What is the most likely explanation?
AThe wheeze is unrelated to the eye drops
BThe eye drops contain an allergen that causes hay fever and asthma
CTimolol is absorbed and blocks beta-2 receptors in the airways
DTimolol activates histamine receptors in the lungs
Kunci jawaban
1. D · Inhibits 5-alpha reductase and slowly shrinks the prostate
2. A · Olanzapine
3. D · Induce ovulation in women with infertility
4. D · Kelenjar adrenal tertekan dan mungkin tidak membuat cukup kortisol
5. A · It must be diluted and given as an infusion, never as an IV push
6. D · As a rapid IV push followed by a fast saline flush
7. D · Menggandakan kadar keadaan tunak tetapi tidak mengubah waktu untuk mencapainya
8. C · Timolol is absorbed and blocks beta-2 receptors in the airways
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