Lembar kerja Farmakologi dengan jawaban

Obat yang namanya berakhiran "-olol", seperti atenolol, termasuk golongan apa?

1. APenghambat ACE
2. BStatin
3. CPenyekat beta
4. DPenyekat kanal kalsium

Why is folinic acid (leucovorin) given after high-dose methotrexate?

1. ATo protect normal cells from methotrexate toxicity
2. BTo make methotrexate act faster on the tumour
3. CTo prevent nausea and vomiting after the methotrexate
4. DTo treat an allergic reaction to methotrexate

On the WHO analgesic ladder, which drugs form the first step?

1. AStrong opioids such as morphine given intravenously
2. BNon-opioids such as paracetamol and NSAIDs
3. CWeak opioids such as codeine or tramadol, used on their own
4. DLocal anaesthetic nerve blocks for all patients

Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?

1. AAlpha-1 blockers
2. BACE inhibitors
3. CAngiotensin II receptor blockers
4. DThiazide diuretics

Besides lithium levels, which blood tests are monitored in long-term lithium treatment?

1. ATroponin and CK-MB
2. BINR and fibrinogen
3. CLiver enzymes, serum amylase and lipase
4. DKidney function and thyroid function

Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?

1. ASubcutaneous in the abdomen
2. BIntravenous infusion over 30 minutes
3. CDeep intramuscular only
4. DIntravenous push

A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?

1. AThe total level is high, but the laboratory is wrong
2. BLow albumin speeds up phenytoin metabolism
3. CLow albumin makes phenytoin bind more tightly, so the drug is less active
4. DMore phenytoin is unbound when albumin is low, so free levels rise

Suatu obat memiliki waktu paruh 6 jam. Kadar plasmanya 80 mg/L. Dengan asumsi eliminasi orde pertama dan tanpa dosis tambahan, berapa kadarnya setelah 18 jam?

1. A20 mg/L
2. B26,7 mg/L
3. C10 mg/L
4. D40 mg/L