Lembar kerja Farmakologi dengan jawaban

Statin seperti atorvastatin menurunkan kolesterol dengan menghambat enzim apa?

1. ASiklooksigenase
2. BLipoprotein lipase
3. CEnzim pengubah angiotensin
4. DHMG-CoA reduktase

Which drug reverses the sedation of a benzodiazepine overdose?

1. AAtropine
2. BFlumazenil
3. CNaloxone
4. DProtamine sulfate

Methylphenidate, used in ADHD, belongs to which class?

1. AOpioid analgesics
2. BAntipsychotics (dopamine blockers)
3. CBenzodiazepines
4. DCentral nervous system stimulants

A nurse has a needlestick injury from a patient with HIV. When should post-exposure prophylaxis start?

1. AAs soon as possible, and within 72 hours at the latest
2. BOnly after the nurse's HIV test turns positive
3. COnly if the patient's viral load is above a set level
4. DAfter one week, when the risk of infection is clearer

Which early signs suggest systemic toxicity from a local anaesthetic?

1. ANumbness around the mouth, metallic taste and tinnitus
2. BHeavy sweating, salivation and diarrhoea
3. CItchy rash and swelling only at the injection site
4. DPinpoint pupils and slow, shallow breathing

Why is IV promethazine given with great caution?

1. AIt causes a severe rise in blood pressure when it is given intravenously
2. BIt is a strong opioid that causes addiction
3. CIt can cause severe tissue injury if it leaks or enters an artery
4. DIt causes immediate kidney failure

Volume distribusi suatu obat sangat besar (misalnya 500 L pada orang dewasa). Apa artinya?

1. AObat banyak diambil ke dalam jaringan
2. BObat tidak bisa diberikan secara intravena
3. CObat cepat diekskresikan ginjal
4. DObat hampir seluruhnya tetap berada di kompartemen plasma

A patient on digoxin is started on amiodarone. What change should the nurse expect?

1. ADigoxin levels rise, so the digoxin dose is often reduced
2. BAmiodarone levels fall to zero
3. CNo interaction is expected
4. DDigoxin levels fall sharply, so the digoxin dose is doubled