Lembar kerja Farmakologi dengan jawaban

Apa yang digambarkan oleh "efikasi" suatu obat?

1. AEfek maksimum yang dapat dihasilkan obat
2. BKecepatan penyerapan obat
3. CBagian dosis yang terikat pada protein plasma
4. DDosis yang diperlukan untuk menghasilkan separuh efek

Apa arti "waktu paruh" suatu obat?

1. AWaktu agar konsentrasi plasma turun menjadi setengahnya
2. BSetengah dari lama obat berada di tubuh
3. CWaktu sampai obat mulai bekerja
4. DWaktu agar setengah dosis diserap dari usus

How does rasagiline help in Parkinson's disease?

1. AIt is converted directly into dopamine inside brain neurones
2. BIt blocks acetylcholine receptors in the gut
3. CIt inhibits MAO-B, so brain dopamine is broken down more slowly
4. DIt blocks dopamine receptors in the brain

A man takes finasteride. What should be explained about handling the tablets?

1. APregnant women should not handle crushed or broken tablets
2. BAnyone can handle the tablets, as they contain no active drug
3. CThe tablets must be crushed before swallowing
4. DThe tablets must be stored in the fridge

After naloxone reverses an opioid overdose, why must the patient be watched closely?

1. ANaloxone often causes severe low blood glucose a few hours after the dose
2. BNaloxone itself causes respiratory depression at high doses
3. CNaloxone may wear off before the opioid does, so breathing can slow again
4. DNaloxone makes the opioid stay longer in the body

How should a patient store sublingual glyceryl trinitrate (nitroglycerin) tablets?

1. AIn the original dark glass bottle, away from heat, light and moisture
2. BIn a plastic weekly pill box with other tablets
3. CLoose in a shirt pocket close to the body for quick access
4. DIn the fridge in a damp, open container to keep them fresh and cool

A patient taking furosemide has a serum potassium of 2,9 mmol/L (mEq/L). Which ECG change is typical of this level?

1. ATall, peaked T waves
2. BA short QT interval with high R waves
3. CWidened QRS with a sine-wave pattern
4. DFlattened T waves and prominent U waves

During general anaesthesia with a volatile agent and suxamethonium (succinylcholine), a patient develops muscle rigidity, rising end-tidal CO₂ and a fast-rising temperature. Which drug is the specific treatment?

1. ANeostigmine
2. BParacetamol
3. CDantrolene
4. DNaloxone