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Nama: ____________________ Tanggal: ____________
1.Mudah
Organ mana yang terutama memetabolisme sebagian besar obat?
AHati
BLimpa
CGinjal
DParu-paru
2.Mudah
Which of these is a second-generation (atypical) antipsychotic?
AFluphenazine
BChlorpromazine
CHaloperidol
DOlanzapine
3.Mudah
Famotidine belongs to which drug class?
AProton pump inhibitors
BAntacids
CProstaglandin analogues
DH2 receptor antagonists
4.Sedang
A patient starting niacin (nicotinic acid) complains of flushing and warmth after doses. Which advice may reduce this?
ATake the niacin with a hot drink so that it dissolves and acts faster
BTake it on an empty stomach in a hot bath
CTake aspirin 30 minutes before the niacin, if the prescriber agrees
DDouble the dose to build tolerance faster
5.Sedang
How should oral potassium chloride tablets be taken?
AOn an empty stomach with only a small sip of water, then lie down
BLying down straight after the dose
CCrushed and dissolved under the tongue
DWith food and plenty of water, swallowed whole if slow-release
6.Sedang
A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?
AAn anticholinergic such as benzatropine (benztropine)
BNaloxone
CDantrolene by mouth to relax the twisted neck muscles
DA second dose of haloperidol
7.Sulit
A patient with heart failure starts taking naproxen regularly for back pain. Why is this a concern?
ANSAIDs block the absorption of furosemide completely
BNSAIDs cause salt and water retention and can worsen heart failure
CNSAIDs lower potassium, which makes digoxin and diuretics fail
DNSAIDs increase heart contractility too much
8.Sulit
A patient with an epidural infusion of local anaesthetic becomes hypotensive. What is the most likely mechanism?
AThe epidural catheter has caused heavy bleeding
BThe local anaesthetic causes a severe allergic reaction
CThe drug increases urine output and causes dehydration
DBlockade of sympathetic nerves causes vasodilation
Kunci jawaban
1. A · Hati
2. D · Olanzapine
3. D · H2 receptor antagonists
4. C · Take aspirin 30 minutes before the niacin, if the prescriber agrees
5. D · With food and plenty of water, swallowed whole if slow-release
6. A · An anticholinergic such as benzatropine (benztropine)
7. B · NSAIDs cause salt and water retention and can worsen heart failure
8. D · Blockade of sympathetic nerves causes vasodilation
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