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Nama: ____________________ Tanggal: ____________
1.Mudah
Mesalazine (mesalamine) is used mainly to treat:
AUlcerative colitis
BPeptic ulcer
CGallstones
DIrritable bowel syndrome with constipation
2.Mudah
Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:
AIncrease the production of neutrophils
BLower the white cell count in leukaemia
CStop bleeding from wounds
DIncrease the production of platelets
3.Mudah
Apa arti "waktu paruh" suatu obat?
AWaktu sampai obat mulai bekerja
BWaktu agar konsentrasi plasma turun menjadi setengahnya
CSetengah dari lama obat berada di tubuh
DWaktu agar setengah dosis diserap dari usus
4.Sedang
A nurse realises that a patient has been given the wrong dose of a medicine. What is the first action?
AWait to see whether the patient notices
BCorrect the chart so it shows the right dose
CComplete the incident report before anything else
DAssess the patient for effects of the error
5.Sedang
How should a patient take oral alendronate?
ACrushed into yoghurt with calcium supplements
BWith breakfast and coffee to protect the stomach
CWith plain water on an empty stomach, staying upright for 30 minutes
DWith milk at bedtime, then lying down straight away to aid absorption
6.Sedang
Efek samping mana yang khas untuk metoklopramid, terutama pada orang muda?
AKonstipasi berat
BGlukosa darah rendah
CGangguan gerak ekstrapiramidal seperti distonia akut
DBatuk kering
7.Sulit
A patient with heart failure starts taking naproxen regularly for back pain. Why is this a concern?
ANSAIDs increase heart contractility too much
BNSAIDs lower potassium, which makes digoxin and diuretics fail
CNSAIDs block the absorption of furosemide completely
DNSAIDs cause salt and water retention and can worsen heart failure
8.Sulit
Why is pethidine (meperidine) avoided in older people and in kidney impairment?
AIt has no pain-relieving effect in older people
BIt is not absorbed from the gut when kidney function is poor
CIts metabolite norpethidine builds up and can cause seizures
DIt causes severe hypoglycaemia in these groups
Kunci jawaban
1. A · Ulcerative colitis
2. A · Increase the production of neutrophils
3. B · Waktu agar konsentrasi plasma turun menjadi setengahnya
4. D · Assess the patient for effects of the error
5. C · With plain water on an empty stomach, staying upright for 30 minutes
6. C · Gangguan gerak ekstrapiramidal seperti distonia akut
7. D · NSAIDs cause salt and water retention and can worsen heart failure
8. C · Its metabolite norpethidine builds up and can cause seizures
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