Lembar kerja Farmakologi dengan jawaban

Apa yang dijelaskan oleh "bioavailabilitas"?

1. ASeberapa cepat obat diekskresikan
2. BBagian dosis yang mencapai sirkulasi sistemik tanpa berubah
3. CBagian dosis yang terikat pada protein plasma dalam sirkulasi
4. DSeberapa kuat obat berikatan dengan reseptornya

Naltrexone helps in alcohol use disorder because it:

1. ASpeeds up the liver breakdown of alcohol
2. BBlocks opioid receptors, reducing reward and craving
3. CCauses vomiting and flushing whenever alcohol is drunk
4. DReplaces alcohol as a sedative

What is enzyme induction?

1. AA drug causes an allergic reaction to enzymes
2. BA drug speeds up liver enzymes, so other drugs are broken down faster
3. CA drug is converted into an enzyme in the body
4. DA drug blocks liver enzymes, so other drugs build up in the blood

A patient taking levodopa finds that the drug works poorly after large meals. Which advice is most appropriate?

1. ATake the drug only at bedtime
2. BTake every dose with a large glass of milk and a protein snack
3. CDouble the dose after each meal
4. DAvoid taking doses at the same time as high-protein meals

What should the nurse teach a patient starting nitrofurantoin?

1. ATake it with food, and the urine may turn dark yellow or brown
2. BTake it on an empty stomach with an antacid
3. CStop it as soon as the burning settles
4. DExpect blue urine, which shows that the drug is working well

Which assessment is most important before giving a dose of IV morphine?

1. ARespiratory rate and level of sedation
2. BBlood glucose and temperature, checked before each dose
3. CPupil size and hearing
4. DBowel sounds and urine colour

Why is glibenclamide (glyburide) generally avoided in older adults?

1. AIt causes severe weight loss and muscle wasting in older people
2. BIt is not absorbed in people over 65
3. CIt is long-acting and can cause prolonged, severe hypoglycaemia
4. DIt causes high blood glucose in older adults

Apa mekanisme kerja utama penghambat pompa proton seperti omeprazol?

1. APenyekatan kompetitif reseptor histamin H2 di sel parietal
2. BMelapisi tukak untuk melindunginya
3. CMenetralkan asam di lambung
4. DPenghambatan ireversibel H⁺/K⁺-ATPase di sel parietal