Lembar kerja Farmakologi dengan jawaban

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-2 (COX-2)
2. BPhospholipase A2
3. CCyclo-oxygenase-1 (COX-1)
4. DLipoxygenase

Famotidine belongs to which drug class?

1. AProstaglandin analogues
2. BH2 receptor antagonists
3. CAntacids
4. DProton pump inhibitors

Mengapa aspirin dosis rendah diberikan kepada sebagian penderita penyakit jantung?

1. AUntuk mengurangi agregasi trombosit dan mencegah bekuan
2. BUntuk menurunkan kadar kolesterol darah dan menstabilkan plak
3. CUntuk segera meredakan nyeri dada
4. DUntuk memperlambat denyut jantung

Sumatriptan is contraindicated in which patient?

1. AA patient with iron deficiency anaemia
2. BA patient with a recent ankle sprain
3. CA patient with mild asthma
4. DA patient with coronary artery disease

When should a patient take a once-daily proton pump inhibitor such as omeprazole?

1. AWith a glass of milk at bedtime, when acid output is highest
2. BOnly when heartburn is severe
3. CStraight after a large evening meal
4. DAbout 30–60 minutes before the first meal of the day

Antipsikotik tipikal seperti haloperidol terutama bekerja dengan memblokir:

1. AReseptor dopamin D2
2. BAmbilan kembali serotonin
3. CAsetilkolinesterase
4. DReseptor GABA-A

In myxoedema coma, why is hydrocortisone often given before or with thyroid hormone?

1. AThyroid hormone is inactive unless hydrocortisone is given
2. BHydrocortisone prevents the hypoglycaemia caused by levothyroxine
3. CHydrocortisone makes thyroid hormone work faster
4. DThyroid hormone can trigger adrenal crisis if cortisol is also low

Beberapa reseptor menunjukkan aktivitas bahkan tanpa agonis. Apa perbedaan agonis inversi (inverse agonist) dengan antagonis netral pada reseptor semacam itu?

1. AAgonis inversi menghancurkan reseptor secara permanen
2. BAgonis inversi menaikkan aktivitas di atas tingkat dasar
3. CAgonis inversi menurunkan aktivitas di bawah tingkat dasar
4. DAgonis inversi tidak berefek bila diberikan sendiri