Scheda di esercizi di Farmacologia con soluzioni

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Nome: ____________________   Data: ____________

1.Facile

Stimulation of which receptor increases heart rate and the force of contraction?

  1. ABeta-2 adrenergic receptor
  2. BAlpha-2 adrenergic receptor
  3. CMuscarinic M2 receptor
  4. DBeta-1 adrenergic receptor
2.Facile

Che cosa descrive la «biodisponibilità»?

  1. ALa velocità di eliminazione di un farmaco
  2. BLa frazione di una dose che raggiunge immodificata la circolazione sistemica
  3. CLa frazione di una dose che è legata alle proteine plasmatiche in circolo
  4. DLa forza con cui un farmaco si lega al recettore
3.Facile

What is an "adjuvant analgesic"?

  1. AA placebo given to test whether pain is real
  2. BA strong opioid used only for severe pain at the end of life
  3. CA drug that reverses the effects of opioids
  4. DA drug for another condition that also relieves some pain
4.Media

Which adverse effect is a well-known risk of zidovudine?

  1. AOrange-red colouring of the urine and tears
  2. BBone marrow suppression, especially anaemia
  3. CGum overgrowth
  4. DRed–green colour blindness
5.Media

A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?

  1. AAn anticholinergic such as benzatropine (benztropine)
  2. BNaloxone
  3. CA second dose of haloperidol
  4. DDantrolene by mouth to relax the twisted neck muscles
6.Media

A patient takes regular paracetamol (acetaminophen) at home. Which teaching point best prevents accidental overdose?

  1. ACheck cold and flu remedies, as many also contain paracetamol
  2. BUse paracetamol only on an empty stomach
  3. CTake paracetamol with alcohol to improve absorption
  4. DTake an extra dose if the first one does not work within 10 minutes
7.Difficile

A patient taking long-term morphine for cancer pain becomes very sedated with slow breathing. Why is naloxone given in small, diluted doses?

  1. ATo make the effect of naloxone last longer than morphine
  2. BTo restore breathing without causing severe withdrawal and pain
  3. CBecause naloxone is toxic to the liver in large doses
  4. DBecause naloxone is much more potent and toxic in patients with cancer
8.Difficile

A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?

  1. ABone marrow suppression, because both drugs inhibit folate metabolism
  2. BLoss of antibiotic effect because methotrexate binds trimethoprim
  3. CHypoglycaemia from reduced liver glucose output
  4. DSevere hypertension from the combination

Soluzioni

  1. 1. D · Beta-1 adrenergic receptor
  2. 2. B · La frazione di una dose che raggiunge immodificata la circolazione sistemica
  3. 3. D · A drug for another condition that also relieves some pain
  4. 4. B · Bone marrow suppression, especially anaemia
  5. 5. A · An anticholinergic such as benzatropine (benztropine)
  6. 6. A · Check cold and flu remedies, as many also contain paracetamol
  7. 7. B · To restore breathing without causing severe withdrawal and pain
  8. 8. A · Bone marrow suppression, because both drugs inhibit folate metabolism

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