Scheda di esercizi di Farmacologia con soluzioni

Which of these drugs has a narrow therapeutic index?

1. ALithium
2. BOmeprazole
3. CAmoxicillin
4. DLoratadine

Quale di queste è una tipica reazione di fase II (coniugazione) del metabolismo dei farmaci?

1. AOssidazione
2. BIdrolisi
3. CRiduzione
4. DGlucuronidazione

Which drug reverses the sedation of a benzodiazepine overdose?

1. AFlumazenil
2. BAtropine
3. CNaloxone
4. DProtamine sulfate

Before starting a TNF-alpha inhibitor such as adalimumab, which test is required?

1. AAn echocardiogram in every patient
2. BScreening for latent tuberculosis
3. CA bone density scan
4. DA glucose tolerance test

Come abbassano la pressione gli ACE-inibitori?

1. ABloccano i canali del calcio di tipo L nelle cellule muscolari lisce vascolari
2. BBloccano la conversione dell'angiotensina I in angiotensina II
3. CAumentano il riassorbimento di sodio nel rene
4. DBloccano i recettori beta-1 del cuore

Which adverse effect of doxorubicin requires monitoring of heart function?

1. ARapid rise in cholesterol
2. BPericarditis caused by infection
3. CSevere hypertension during the infusion itself
4. DCumulative heart muscle damage leading to heart failure

A patient receiving a phenylephrine infusion has a rise in blood pressure and a fall in heart rate. What is the best explanation?

1. APhenylephrine stimulates muscarinic receptors
2. BAlpha-1 vasoconstriction raises blood pressure and causes reflex bradycardia
3. CThe fall in heart rate shows phenylephrine toxicity of the AV node
4. DPhenylephrine directly blocks beta-1 receptors in the heart's conduction system

Why is vincristine labelled "for intravenous use only – fatal if given by other routes"?

1. ASubcutaneous injection makes the drug inactive
2. BOral vincristine causes immediate anaphylaxis
3. CIntramuscular injection causes severe and prolonged hypoglycaemia
4. DAccidental intrathecal injection causes fatal ascending neurotoxicity