Scheda di esercizi di Farmacologia con soluzioni

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Nome: ____________________   Data: ____________

1.Facile

In the United States, what is a "boxed warning" (black box warning) on a drug label?

  1. AA label showing that the drug is a controlled substance with abuse potential
  2. BA note that the drug is available without prescription
  3. CA sign that the drug must be stored in a dark box
  4. DThe strongest FDA warning about a serious or life-threatening risk
2.Facile

Which drug is used as an antidote for cyanide poisoning?

  1. AProtamine sulfate
  2. BVitamin K
  3. CDeferoxamine
  4. DHydroxocobalamin
3.Facile

What is the normal serum sodium range in adults?

  1. A135–145 mmol/L
  2. B150–165 mmol/L
  3. C95–105 mmol/L
  4. D3,5–5,0 mmol/L
4.Media

During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?

  1. ASevere hypoglycaemia caused by the drug
  2. BA common infusion reaction to amphotericin B
  3. CA sign that the drug has been given into an artery
  4. DA sign that the fungal infection is cured
5.Media

After several years of levodopa treatment, which problem is common?

  1. APermanent hearing loss
  2. BDyskinesias and "on–off" fluctuations in response
  3. CSevere hypoglycaemia after each dose
  4. DComplete and permanent loss of all Parkinson's symptoms
6.Media

Why is a spacer recommended with a metered-dose inhaler?

  1. AIt turns the inhaler into a nebuliser
  2. BMore drug reaches the lungs and less stays in the mouth
  3. CIt doubles the dose of drug released by each puff of the inhaler
  4. DIt removes the need to shake the inhaler
7.Difficile

Before starting rituximab, patients are tested for hepatitis B. Why?

  1. AHepatitis B infection makes rituximab completely ineffective
  2. BRituximab can reactivate hepatitis B and cause liver failure
  3. CRituximab is made from the hepatitis B virus
  4. DRituximab is a vaccine against hepatitis B
8.Difficile

A woman with chronic hypertension who takes lisinopril is now pregnant. What is the key concern?

  1. ALisinopril has no known fetal effects and should be continued
  2. BACE inhibitors harm fetal kidneys, so a safer drug is used
  3. CLisinopril works better in pregnancy, so the dose should be increased
  4. DAll antihypertensives must be stopped in pregnancy

Soluzioni

  1. 1. D · The strongest FDA warning about a serious or life-threatening risk
  2. 2. D · Hydroxocobalamin
  3. 3. A · 135–145 mmol/L
  4. 4. B · A common infusion reaction to amphotericin B
  5. 5. B · Dyskinesias and "on–off" fluctuations in response
  6. 6. B · More drug reaches the lungs and less stays in the mouth
  7. 7. B · Rituximab can reactivate hepatitis B and cause liver failure
  8. 8. B · ACE inhibitors harm fetal kidneys, so a safer drug is used

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