Scheda di esercizi di Farmacologia gratuita e stampabile: 8 esercizi dal livello facile a quello d’esame, con le soluzioni. Stampala o salvala come PDF.
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Nome: ____________________ Data: ____________
1.Facile
In quale fase della sperimentazione clinica un nuovo farmaco viene di solito somministrato per la prima volta all'uomo, spesso a volontari sani?
AFase III
BFase IV
CFase II
DFase I
2.Facile
Finasteride is used in benign prostatic hyperplasia because it:
ARelaxes smooth muscle in the prostate within hours of the first dose
BIncreases testosterone production
CKills bacteria in the prostate
DInhibits 5-alpha reductase and slowly shrinks the prostate
3.Facile
La sertralina, un antidepressivo, aumenta il livello di quale neurotrasmettitore nella sinapsi?
ASerotonina
BAcetilcolina
CDopamina
DGABA
4.Media
Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?
AThiazide diuretics
BAngiotensin II receptor blockers
CACE inhibitors
DAlpha-1 blockers
5.Media
Which patient should usually not use the combined oral contraceptive pill?
AA 38-year-old woman who smokes 20 cigarettes a day
BA 22-year-old non-smoker with acne
CA 30-year-old non-smoker with no medical problems
DA 25-year-old woman with heavy periods
6.Media
While giving medicines, a patient says, "That pill looks different from the one I usually take." What should the nurse do?
AExplain that only the staff decide which medicines are given
BReassure the patient and give the pill anyway
CStop and recheck the order and the medicine before giving it
DGive the pill and check the chart afterwards
7.Difficile
A patient taking azathioprine is prescribed allopurinol for gout. What is the main danger?
ASevere hypertension from the combination
BLiver enzyme induction, making azathioprine ineffective
CGout becomes worse because allopurinol is inactivated by azathioprine
DSevere bone marrow suppression, because azathioprine breakdown is reduced
8.Difficile
A patient with severe liver cirrhosis needs a benzodiazepine for alcohol withdrawal. Why is lorazepam often chosen instead of diazepam?
ALorazepam is a stronger anticonvulsant than all other benzodiazepines
BLorazepam is cleared by simple conjugation and has no active metabolites
CLorazepam is excreted unchanged in the urine without any metabolism
DLorazepam does not cause sedation in liver disease
Soluzioni
1. D · Fase I
2. D · Inhibits 5-alpha reductase and slowly shrinks the prostate
3. A · Serotonina
4. A · Thiazide diuretics
5. A · A 38-year-old woman who smokes 20 cigarettes a day
6. C · Stop and recheck the order and the medicine before giving it
7. D · Severe bone marrow suppression, because azathioprine breakdown is reduced
8. B · Lorazepam is cleared by simple conjugation and has no active metabolites
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