Scheda di esercizi di Farmacologia con soluzioni

Alendronate, used for osteoporosis, belongs to which class?

1. ABisphosphonates
2. BCorticosteroids
3. CCalcium channel blockers
4. DThyroid hormones

Which intramuscular site is generally preferred for adults because it is far from major nerves and vessels?

1. AVentrogluteal
2. BDorsogluteal
3. CDeltoid for large volumes
4. DForearm

Che cos'è l'indice terapeutico?

1. AIl tempo per raggiungere lo stato stazionario
2. BIl rapporto tra dose tossica e dose efficace
3. CLa percentuale di una dose orale che raggiunge la circolazione sistemica
4. DIl numero di dosi al giorno

I macrolidi come la claritromicina agiscono:

1. ABloccando la sintesi dell'acido folico
2. BInibendo la sintesi della parete cellulare
3. CLegandosi alla subunità ribosomiale 50S e inibendo la sintesi proteica
4. DInibendo la DNA girasi

Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?

1. ASubcutaneous in the abdomen
2. BDeep intramuscular only
3. CIntravenous infusion over 30 minutes
4. DIntravenous push

A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?

1. AHalve the hydrocortisone to reduce side effects
2. BIncrease the dose as instructed (sick-day rules) and seek help if vomiting
3. CStop the hydrocortisone until the fever settles, to let the body recover
4. DMake no change, as illness does not affect cortisol needs

Which finding most favours serotonin syndrome over neuroleptic malignant syndrome?

1. ARapid onset with hyperreflexia and clonus
2. BA very high creatine kinase
3. CRecent start of an antipsychotic drug
4. DSlow onset over days with lead-pipe rigidity

Why may omeprazole be avoided in a patient taking clopidogrel?

1. AIt speeds up kidney excretion of clopidogrel
2. BIt increases clopidogrel absorption from the gut and causes bleeding
3. CIt binds clopidogrel in the stomach and makes it insoluble
4. DIt inhibits CYP2C19, so less clopidogrel is converted to its active form