Scheda di esercizi di Farmacologia con soluzioni

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Nome: ____________________   Data: ____________

1.Facile

How does rasagiline help in Parkinson's disease?

  1. AIt inhibits MAO-B, so brain dopamine is broken down more slowly
  2. BIt blocks acetylcholine receptors in the gut
  3. CIt is converted directly into dopamine inside brain neurones
  4. DIt blocks dopamine receptors in the brain
2.Facile

Which drug can be used in beta blocker overdose because it raises heart rate through a non-adrenergic pathway?

  1. AInsulin
  2. BFlumazenil
  3. CNaloxone
  4. DGlucagon
3.Facile

Naltrexone helps in alcohol use disorder because it:

  1. ASpeeds up the liver breakdown of alcohol
  2. BBlocks opioid receptors, reducing reward and craving
  3. CReplaces alcohol as a sedative
  4. DCauses vomiting and flushing whenever alcohol is drunk
4.Media

Why are many drugs started at lower doses in older adults?

  1. AKidney and liver clearance often decline, and sensitivity to drugs increases
  2. BOlder adults always weigh more than younger adults, so drugs last longer
  3. COlder adults absorb no drugs from the stomach
  4. DLower doses are cheaper for older patients
5.Media

100 mL of an antibiotic is to be given over 30 minutes using a giving set of 20 drops/mL. What is the drip rate?

  1. AAbout 33 drops per minute
  2. BAbout 20 drops per minute
  3. CAbout 100 drops per minute
  4. DAbout 67 drops per minute
6.Media

Which blood test is commonly used to monitor a continuous infusion of unfractionated heparin?

  1. AActivated partial thromboplastin time (aPTT)
  2. BSerum potassium
  3. CHaemoglobin A1c
  4. DINR (international normalised ratio, prothrombin time)
7.Difficile

An older patient with coronary artery disease is starting levothyroxine for hypothyroidism. Why is a low starting dose used?

  1. ALevothyroxine causes severe hypoglycaemia in older patients
  2. BOlder patients absorb levothyroxine much better, so small doses are all they need
  3. CHigh starting doses cause permanent hypothyroidism
  4. DFast replacement raises cardiac oxygen demand and can cause angina
8.Difficile

Why is glibenclamide (glyburide) generally avoided in older adults?

  1. AIt causes severe weight loss and muscle wasting in older people
  2. BIt is long-acting and can cause prolonged, severe hypoglycaemia
  3. CIt causes high blood glucose in older adults
  4. DIt is not absorbed in people over 65

Soluzioni

  1. 1. A · It inhibits MAO-B, so brain dopamine is broken down more slowly
  2. 2. D · Glucagon
  3. 3. B · Blocks opioid receptors, reducing reward and craving
  4. 4. A · Kidney and liver clearance often decline, and sensitivity to drugs increases
  5. 5. D · About 67 drops per minute
  6. 6. A · Activated partial thromboplastin time (aPTT)
  7. 7. D · Fast replacement raises cardiac oxygen demand and can cause angina
  8. 8. B · It is long-acting and can cause prolonged, severe hypoglycaemia

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